{"id":"reinforced-vaccination-schedule","safety":{"commonSideEffects":[{"rate":null,"effect":"Local injection site reactions (pain, erythema, swelling)"},{"rate":null,"effect":"Systemic reactions (fever, fatigue, myalgia)"},{"rate":null,"effect":"Headache"}]},"_chembl":{"chemblId":"CHEMBL2107962","moleculeType":"Vaccine component"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Reinforced vaccination schedules involve repeated or additional doses of vaccines given at strategic time intervals to boost and sustain protective immunity. This approach increases the breadth and durability of immune responses, particularly antibody titers and T-cell memory, compared to standard vaccination schedules. The reinforcement strategy is designed to overcome waning immunity and provide longer-lasting protection against infectious diseases.","oneSentence":"A reinforced vaccination schedule enhances immune response by administering vaccine doses at optimized intervals to maximize antibody production and immunological memory.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:04:32.633Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Enhancement of immune response through optimized vaccination schedules for infectious disease prevention"}]},"trialDetails":[{"nctId":"NCT04540653","phase":"PHASE4","title":"Immunogenicity of the Hepatitis B Vaccine","status":"UNKNOWN","sponsor":"Universidade Federal de Goias","startDate":"2017-07-29","conditions":"Vaccine Response Impaired, Hepatitis B, Aging","enrollment":240},{"nctId":"NCT03571932","phase":"","title":"Assessment of Family Planning and Immunization Service Integration in Liberia","status":"COMPLETED","sponsor":"Jhpiego","startDate":"2016-11","conditions":"Contraception, Contraceptive Usage, Contraception Behavior","enrollment":36}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":28,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Reinforced vaccination schedule","genericName":"Reinforced vaccination schedule","companyName":"Universidade Federal de Goias","companyId":"universidade-federal-de-goias","modality":"Biologic","firstApprovalDate":"","aiSummary":"A reinforced vaccination schedule enhances immune response by administering vaccine doses at optimized intervals to maximize antibody production and immunological memory. Used for Enhancement of immune response through optimized vaccination schedules for infectious disease prevention.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}