{"id":"rectalgan-mousse","safety":{"commonSideEffects":[{"rate":null,"effect":"Local irritation or burning sensation"},{"rate":null,"effect":"Allergic contact dermatitis"},{"rate":null,"effect":"Transient stinging"}]},"_chembl":{"chemblId":"CHEMBL1201131","moleculeType":"Small molecule","molecularWeight":"338.44"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The mousse formulation delivers active pharmaceutical ingredients directly to the rectal mucosa, where they exert local anesthetic properties to reduce pain sensation and anti-inflammatory effects to decrease tissue inflammation. This localized delivery approach minimizes systemic absorption while providing targeted symptom relief in the rectal region.","oneSentence":"Rectalgan Mousse is a topical rectal formulation that provides local anesthetic and anti-inflammatory effects for symptomatic relief of rectal pain and discomfort.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:04:21.327Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Rectal pain and discomfort associated with hemorrhoids, anal fissures, and other rectal conditions"}]},"trialDetails":[{"nctId":"NCT03355846","phase":"PHASE4","title":"Pain and Bleeding in Subjects With Acute Anal Fissure: Comparative Evaluation of Three Treatments","status":"COMPLETED","sponsor":"University of Roma La Sapienza","startDate":"2018-05-01","conditions":"Acute Anal Fissure","enrollment":99}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":388,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Rectalgan Mousse","genericName":"Rectalgan Mousse","companyName":"University of Roma La Sapienza","companyId":"university-of-roma-la-sapienza","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Rectalgan Mousse is a topical rectal formulation that provides local anesthetic and anti-inflammatory effects for symptomatic relief of rectal pain and discomfort. Used for Rectal pain and discomfort associated with hemorrhoids, anal fissures, and other rectal conditions.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}