{"id":"rak-therapy","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site pain or swelling"},{"rate":null,"effect":"Temporary inflammation"}]},"_chembl":{"chemblId":"CHEMBL1271735","moleculeType":"Protein","molecularWeight":"373.46"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"RAK (Regenerative Autologous Kinetic) therapy involves harvesting and processing a patient's own bone marrow cells, which are then administered to damaged or degenerative tissues to stimulate healing and regeneration. The mechanism relies on the immunomodulatory and regenerative properties of bone marrow stem cells and progenitor cells to reduce inflammation and promote tissue repair.","oneSentence":"RAK therapy is a regenerative medicine approach that uses autologous bone marrow-derived cells to promote tissue repair and regeneration.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:03:38.873Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Osteoarthritis and joint degeneration"},{"name":"Tissue repair and regeneration"}]},"trialDetails":[{"nctId":"NCT07212933","phase":"PHASE2","title":"The Safety and Clinical Efficacy of RAK Cell Therapy in Late-stage Gastric Cancer: A Randomized Controlled Trial","status":"RECRUITING","sponsor":"Chinese PLA General Hospital","startDate":"2025-07-01","conditions":"Gastric (Stomach) Cancer, Biological Therapy, Immunotherapy","enrollment":90},{"nctId":"NCT06858384","phase":"NA","title":"RAK-PRIDE: Optimizing Proton Pump Inhibitor Use Through Education and Intervention","status":"RECRUITING","sponsor":"RAK Medical and Health Sciences University","startDate":"2025-03","conditions":"Proton Pump Inhibitors, Deprescribing, Inappropriate Use","enrollment":479},{"nctId":"NCT05459441","phase":"EARLY_PHASE1","title":"Efficacy and Safety Evaluation of Percutaneous Ommaya Capsule Injection of Autologous Bi-dimensional Specific T Cells in the Treatment of Glioma and in Combination With Pemetrexed in the Treatment of Brain/Meningeal Metastases","status":"UNKNOWN","sponsor":"Shanghai Pudong Hospital","startDate":"2022-01-01","conditions":"Glioma, Brain Metastases","enrollment":30},{"nctId":"NCT03108287","phase":"PHASE4","title":"Adding Bismuth to Rabeprazole-based First-line Triple Therapy Does Not Improve the Eradication of Helicobacter Pylori","status":"COMPLETED","sponsor":"Kaohsiung Medical University Chung-Ho Memorial Hospital","startDate":"2013-04-01","conditions":"Helicobacter Pylori Infection","enrollment":162}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":506,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["rabeprazole, amoxicillin, clarithromycin"],"phase":"marketed","status":"active","brandName":"RAK therapy","genericName":"RAK therapy","companyName":"Kaohsiung Medical University Chung-Ho Memorial Hospital","companyId":"kaohsiung-medical-university-chung-ho-memorial-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"RAK therapy is a regenerative medicine approach that uses autologous bone marrow-derived cells to promote tissue repair and regeneration. Used for Osteoarthritis and joint degeneration, Tissue repair and regeneration.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}