{"id":"radiopharmaceutical-18f-fluorocholine","safety":{"commonSideEffects":[{"rate":"null","effect":"Radiation exposure"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"This is achieved through the use of 18F-fluorocholine, a radiolabeled choline analog that is taken up by cells with high choline demand, such as cancer cells. The resulting images can help identify and stage cancer, as well as monitor treatment response.","oneSentence":"18F-Fluorocholine is a radiopharmaceutical that accumulates in cells with high choline uptake, allowing for imaging of cancer cells.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:31:19.304Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Imaging of prostate cancer, breast cancer, and other choline-avid tumors"}]},"trialDetails":[{"nctId":"NCT03891914","phase":"PHASE3","title":"Prospective Comparison of 18F-choline PET/CT and 18F-FDG PET/CT in the Initial Work-up of Multiple Myeloma","status":"COMPLETED","sponsor":"University Hospital, Bordeaux","startDate":"2019-11-12","conditions":"Myeloma Multiple","enrollment":20},{"nctId":"NCT04965454","phase":"PHASE2","title":"Evaluation of Treatment Predictors Reflecting Beta-catenin Activation in Hepatocellular Carcinoma","status":"RECRUITING","sponsor":"Queen's Medical Center","startDate":"2022-03-28","conditions":"Hepatocellular Carcinoma Non-resectable","enrollment":80},{"nctId":"NCT05622162","phase":"PHASE3","title":"Prospective Comparative Study for Patients With Biochemical Recurrence Prostate Cancer Detecting by 18F-JK-PSMA-7","status":"ACTIVE_NOT_RECRUITING","sponsor":"ITEL Telecomunicazioni Srl","startDate":"2022-12-19","conditions":"Prostate Cancer, 18F- Fluorocholine, PSMA PET","enrollment":106},{"nctId":"NCT01501630","phase":"","title":"Role of PET/CT With Fluorine-18 Tracers of Bone Metastases in Prostate Cancer","status":"COMPLETED","sponsor":"Assistance Publique - Hôpitaux de Paris","startDate":"2011-12","conditions":"Prostate Cancer","enrollment":112}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["18F-Fluorocholine"],"phase":"phase_3","status":"active","brandName":"Radiopharmaceutical 18F-Fluorocholine","genericName":"Radiopharmaceutical 18F-Fluorocholine","companyName":"ITEL Telecomunicazioni Srl","companyId":"itel-telecomunicazioni-srl","modality":"Small molecule","firstApprovalDate":"","aiSummary":"18F-Fluorocholine is a radiopharmaceutical that accumulates in cells with high choline uptake, allowing for imaging of cancer cells. Used for Imaging of prostate cancer, breast cancer, and other choline-avid tumors.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}