{"id":"rabivax-s","safety":{"commonSideEffects":[{"rate":null,"effect":"Local injection site reactions (pain, erythema, swelling)"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Myalgia"},{"rate":null,"effect":"Headache"}]},"_chembl":{"chemblId":"CHEMBL297792","moleculeType":"Small molecule","molecularWeight":"464.57"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Rabivax-S is a live attenuated or recombinant rabies vaccine developed to provide immunization against rabies virus infection. It works by presenting rabies virus antigens (particularly the glycoprotein) to the immune system, triggering both cellular and humoral immune responses that provide protection against rabies virus exposure. The vaccine is designed for post-exposure prophylaxis or pre-exposure immunization.","oneSentence":"Rabivax-S is a recombinant rabies virus vaccine that stimulates immune responses against rabies virus through viral glycoprotein antigens.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:36:53.287Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Rabies post-exposure prophylaxis"},{"name":"Rabies pre-exposure prophylaxis"}]},"trialDetails":[{"nctId":"NCT07183371","phase":"PHASE2","title":"A Study to Assess the Experimental Malaria Vaccines R78C and RH5.1 With Matrix-M in Combination With R21/Matrix-M","status":"ACTIVE_NOT_RECRUITING","sponsor":"University of Oxford","startDate":"2025-12-15","conditions":"Malaria,Falciparum","enrollment":360},{"nctId":"NCT07147400","phase":"PHASE2","title":"Pfs230D1 + R21 in Matrix-M1 in African School Children and Adults","status":"RECRUITING","sponsor":"Serum Institute of India Pvt. Ltd.","startDate":"2025-08-22","conditions":"Prevention of Malaria Transmission and Clinical Malaria","enrollment":1200},{"nctId":"NCT06066294","phase":"PHASE3","title":"A Comparison of Safety and Immunogenicity of Rabies Pre Exposure Prophylaxis Regimen Between Gvt of India Approved and WHO Approved.","status":"UNKNOWN","sponsor":"Kempegowda Institute of Medical Sciences, Bangalore","startDate":"2023-04-03","conditions":"Vaccine Reaction","enrollment":115},{"nctId":"NCT05937113","phase":"PHASE4","title":"Safety and Immunogenicity of the Inactivated Rabies Vaccine RABIVAX-S Administered Intramuscularly and Intradermally","status":"COMPLETED","sponsor":"Vietnam Military Medical University","startDate":"2020-06-13","conditions":"Rabies","enrollment":220},{"nctId":"NCT03656198","phase":"PHASE4","title":"Non-specific Effects of Rabies Vaccine","status":"COMPLETED","sponsor":"Ross University School of Veterinary Medicine","startDate":"2018-08-29","conditions":"Influenza-like Illness, Upper Respiratory Disease, Diarrhea","enrollment":546},{"nctId":"NCT03741270","phase":"PHASE4","title":"Safety of Rabivax-S for Pre-exposure Prophylaxis","status":"COMPLETED","sponsor":"Ross University School of Veterinary Medicine","startDate":"2018-10-24","conditions":"Rabies Vaccine Adverse Reaction","enrollment":159}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":9,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Rabivax-S","genericName":"Rabivax-S","companyName":"University of Oxford","companyId":"university-of-oxford","modality":"Biologic","firstApprovalDate":"","aiSummary":"Rabivax-S is a small molecule vaccine candidate, also known as S 3304 or S-3304, that has been studied in clinical trials for various conditions including malaria, influenza-like illness, upper respiratory disease, and diarrhea. The vaccine has been tested in combination with other interventions, including R21, RH5.1, and R78C, in a Phase IIb randomized controlled trial.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":2,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}