{"id":"quingestanol-acetate","rwe":[],"tags":[{"label":"quingestanol acetate","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Progesterone receptor","category":"target"},{"label":"PGR","category":"gene"},{"label":"G03AA02","category":"atc"},{"label":"Active","category":"status"},{"label":"Postcoital contraception","category":"indication"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["quingestanol acetate"],"offLabel":[],"synonyms":["quingestanol acetate"],"timeline":[],"approvals":[],"ecosystem":[{"indication":"Postcoital contraception","otherDrugs":[{"name":"levonorgestrel","slug":"levonorgestrel","company":"Wyeth Pharms"},{"name":"ulipristal","slug":"ulipristal","company":"Lab Hra Pharma"}],"globalPrevalence":null}],"mechanism":{"target":"Progesterone receptor","targets":[{"gene":"PGR","source":"DrugCentral","target":"Progesterone receptor","protein":"Progesterone receptor"}],"modality":"Small Molecule","drugClass":"quingestanol acetate","explanation":"Think of it like a key fitting into a lock. Quingestanol acetate is the key that fits into the progesterone receptor lock, which is a protein on the surface of cells. When it binds, it sends a signal that prevents the release of an egg from the ovary and also prevents a fertilized egg from implanting in the uterus.","oneSentence":"Quingestanol acetate works by binding to the progesterone receptor, mimicking the effects of progesterone to prevent ovulation and fertilization.","technicalDetail":"Quingestanol acetate acts as a selective progesterone receptor modulator (SPRM), binding to the progesterone receptor and altering its activity to prevent ovulation and implantation, thereby providing postcoital contraception."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2345","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=QUINGESTANOL ACETATE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:29:27.107853","biosimilars":[],"competitors":[{"drugName":"ethinylestradiol","drugSlug":"ethinylestradiol","fdaApproval":"1943-06-25","relationship":"same-class"},{"drugName":"etynodiol","drugSlug":"etynodiol","fdaApproval":"1966-03-23","relationship":"same-class"},{"drugName":"megestrol acetate","drugSlug":"megestrol-acetate","fdaApproval":"1971-08-18","genericCount":10,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"norethisterone","drugSlug":"norethisterone","fdaApproval":"1962-05-21","relationship":"same-class"},{"drugName":"levonorgestrel","drugSlug":"levonorgestrel","fdaApproval":"1968-04-16","patentExpiry":"Sep 7, 2040","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"medroxyprogesterone","drugSlug":"medroxyprogesterone","fdaApproval":"1959-06-18","genericCount":16,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"desogestrel","drugSlug":"desogestrel","fdaApproval":"1992-12-10","relationship":"same-class"},{"drugName":"norgestimate","drugSlug":"norgestimate","fdaApproval":"1989-12-29","relationship":"same-class"},{"drugName":"drospirenone","drugSlug":"drospirenone","fdaApproval":"2019-05-23","patentExpiry":"Jun 28, 2031","patentStatus":"Patent protected","relationship":"same-class"}],"genericName":"quingestanol acetate","indications":{"approved":[{"name":"Postcoital contraception","source":"DrugCentral","snomedId":268463003,"regulator":"FDA"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"ethinylestradiol","brandName":"ethinylestradiol","genericName":"ethinylestradiol","approvalYear":"1943","relationship":"same-class"},{"drugId":"etynodiol","brandName":"etynodiol","genericName":"etynodiol","approvalYear":"1966","relationship":"same-class"},{"drugId":"megestrol-acetate","brandName":"megestrol acetate","genericName":"megestrol acetate","approvalYear":"1971","relationship":"same-class"},{"drugId":"norethisterone","brandName":"norethisterone","genericName":"norethisterone","approvalYear":"1962","relationship":"same-class"},{"drugId":"levonorgestrel","brandName":"levonorgestrel","genericName":"levonorgestrel","approvalYear":"1968","relationship":"same-class"},{"drugId":"medroxyprogesterone","brandName":"medroxyprogesterone","genericName":"medroxyprogesterone","approvalYear":"1959","relationship":"same-class"},{"drugId":"desogestrel","brandName":"desogestrel","genericName":"desogestrel","approvalYear":"1992","relationship":"same-class"},{"drugId":"norgestimate","brandName":"norgestimate","genericName":"norgestimate","approvalYear":"1989","relationship":"same-class"},{"drugId":"drospirenone","brandName":"drospirenone","genericName":"drospirenone","approvalYear":"2019","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"M33GGZ63KG","CHEBI":"CHEBI:135661","INN_ID":"1909","UMLSCUI":"C0139693","ChEMBL_ID":"CHEMBL2105291","KEGG_DRUG":"D05679","DRUGBANK_ID":"DB14679","PUBCHEM_CID":"18142","SECONDARY_CAS_RN":"10592-65-1","MESH_SUPPLEMENTAL_RECORD_UI":"C100039"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":41,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"G03AA02","allCodes":["G03AA02","G03AC04"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"QUINGESTANOL ACETATE","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Quingestanol acetate is a small molecule drug that targets the progesterone receptor. It is classified as a quingestanol acetate and has been approved for postcoital contraception. The original developer and current owner of quingestanol acetate are unknown. Its commercial status, including patent status and generic availability, is also unknown.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":false,"score":2}}