{"id":"quinestradol","rwe":[{"pmid":"1220592","year":"1975","title":"[Effects of estriol and quinestradol administered to pregnant rats on the fetal sex differentiation].","finding":"","journal":"Annali di ostetricia, ginecologia, medicina perinatale","studyType":"Clinical Study"},{"pmid":"4890404","year":"1969","title":"The use of quinestradol in elderly incontinent women, a preliminary report.","finding":"","journal":"Gerontologia clinica","studyType":"Clinical Study"},{"pmid":"6046407","year":"1967","title":"A comparative trial of quinestradol and ethinyl oestradiol.","finding":"","journal":"The British journal of clinical practice","studyType":"Clinical Study"},{"pmid":"4960138","year":"1967","title":"The induction of withdrawal bleeding with quinestradol (pentovis) in spayed monkeys, and some observations on its excretion and that of oestriol in the urine.","finding":"","journal":"The Journal of endocrinology","studyType":"Clinical Study"}],"tags":[{"label":"quinestradol","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"quinestradiol","offLabel":[],"synonyms":["quinestradol","quinestradiol"],"timeline":[],"approvals":[],"brandName":"Quinestradiol","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"quinestradol","explanation":"Think of estrogen as a key that unlocks certain doors in the body, allowing hormones to flow and cells to grow. Quinestradiol is like a fake key that fits into those same locks, allowing it to influence the body's hormonal balance and potentially treat conditions related to estrogen deficiency.","oneSentence":"Quinestradiol works by binding to and activating estrogen receptors, mimicking the effects of estrogen in the body.","technicalDetail":"Quinestradiol is a selective estrogen receptor modulator (SERM) that binds to estrogen receptors (ER) with high affinity, activating or inhibiting downstream signaling pathways depending on the tissue context."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2341","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=QUINESTRADOL","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:29:20.362924","biosimilars":[],"competitors":[],"genericName":"quinestradol","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"422L8173W8","CHEBI":"CHEBI:135506","INN_ID":"1778","RXNORM":"35215","UMLSCUI":"C0072864","ChEMBL_ID":"CHEMBL2107004","PUBCHEM_CID":"14626804","SNOMEDCT_US":"325561002","MESH_SUPPLEMENTAL_RECORD_UI":"C012021"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":4,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"1975 Mar-Apr","pmid":"1220592","title":"[Effects of estriol and quinestradol administered to pregnant rats on the fetal sex differentiation].","journal":"Annali di ostetricia, ginecologia, medicina perinatale"},{"date":"1969","pmid":"4890404","title":"The use of quinestradol in elderly incontinent women, a preliminary report.","journal":"Gerontologia clinica"},{"date":"1967 May","pmid":"6046407","title":"A comparative trial of quinestradol and ethinyl oestradiol.","journal":"The British journal of clinical practice"},{"date":"1967 Mar","pmid":"4960138","title":"The induction of withdrawal bleeding with quinestradol (pentovis) in spayed monkeys, and some observations on its excretion and that of oestriol in the urine.","journal":"The Journal of endocrinology"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Quinestradiol is a small molecule medication. It is also known by the synonyms COLPOVIS, PENTOVIS, and QUINESTRADOL.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}