{"id":"quick-response-amoxicillin-for-5-days","safety":{"commonSideEffects":[{"rate":"5–10","effect":"Diarrhea"},{"rate":"3–5","effect":"Nausea"},{"rate":"1–3","effect":"Rash"},{"rate":"0.1–1","effect":"Allergic reaction / anaphylaxis"},{"rate":"1–3","effect":"Vomiting"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Amoxicillin is a beta-lactam antibiotic that penetrates bacterial cell walls and irreversibly binds to penicillin-binding proteins, preventing the cross-linking of peptidoglycan strands. This disrupts cell wall integrity, leading to bacterial cell lysis and death. It is bactericidal and effective against a broad spectrum of gram-positive and some gram-negative bacteria.","oneSentence":"Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins and blocking peptidoglycan cross-linking.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:03:32.809Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Bacterial infections including otitis media, sinusitis, and respiratory tract infections"},{"name":"Urinary tract infections"},{"name":"Skin and soft tissue infections"},{"name":"Streptococcal pharyngitis"}]},"trialDetails":[{"nctId":"NCT06291012","phase":"PHASE4","title":"Stopping Pneumonia Antibiotherapy Regimen Early","status":"NOT_YET_RECRUITING","sponsor":"University Hospital, Montpellier","startDate":"2024-09-01","conditions":"Community-acquired Pneumonia, Child, Only","enrollment":1100}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Quick response (5 days)"],"phase":"marketed","status":"active","brandName":"Quick response: Amoxicillin for 5 days","genericName":"Quick response: Amoxicillin for 5 days","companyName":"University Hospital, Montpellier","companyId":"university-hospital-montpellier","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Amoxicillin is a small molecule used to treat community-acquired pneumonia in children. According to a clinical trial (NCT06291012), amoxicillin was administered for either 3 days or 5 days in different response groups.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}