{"id":"purified-verocell-rabies-vaccine","safety":{"commonSideEffects":[{"rate":"10-30","effect":"Injection site reactions (pain, erythema, swelling)"},{"rate":"5-15","effect":"Headache"},{"rate":"5-10","effect":"Myalgia"},{"rate":"1-5","effect":"Fever"},{"rate":"1-5","effect":"Nausea"}]},"_chembl":{"chemblId":"CHEMBL2107909","moleculeType":"Vaccine component"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Purified Verocell Rabies Vaccine is an inactivated rabies vaccine produced in Vero cell culture. It contains rabies virus that has been inactivated (killed) and purified to trigger both humoral (antibody) and cell-mediated immune responses. Upon vaccination, the immune system recognizes the viral antigens and develops protective immunity against rabies virus infection.","oneSentence":"This vaccine stimulates the immune system to produce antibodies and cellular immunity against rabies virus by presenting inactivated viral antigens.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:03:20.478Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Rabies post-exposure prophylaxis (PEP) in previously unvaccinated individuals"},{"name":"Rabies pre-exposure prophylaxis (PrEP) in high-risk populations"},{"name":"Rabies post-exposure prophylaxis in previously vaccinated individuals"}]},"trialDetails":[{"nctId":"NCT06433440","phase":"PHASE4","title":"Safety and Immunogenicity of Purified Verocell Rabies Vaccine PVRV Administered Intramuscularly and Intradermally","status":"COMPLETED","sponsor":"University of Peshawar","startDate":"2020-07-01","conditions":"Rabies","enrollment":100},{"nctId":"NCT06066294","phase":"PHASE3","title":"A Comparison of Safety and Immunogenicity of Rabies Pre Exposure Prophylaxis Regimen Between Gvt of India Approved and WHO Approved.","status":"UNKNOWN","sponsor":"Kempegowda Institute of Medical Sciences, Bangalore","startDate":"2023-04-03","conditions":"Vaccine Reaction","enrollment":115},{"nctId":"NCT00260351","phase":"PHASE4","title":"Immunogenicity and Safety of Verorab™ in Indian Population","status":"COMPLETED","sponsor":"Sanofi Pasteur, a Sanofi Company","startDate":"2004-12","conditions":"Rabies","enrollment":405},{"nctId":"NCT01228383","phase":"PHASE2","title":"Rabies Virus Neutralizing Activity and Safety of CL184, a Monoclonal Antibody Cocktail, in Simulated Rabies Post-Exposure Prophylaxis in Healthy Adults","status":"COMPLETED","sponsor":"Crucell Holland BV","startDate":"2011-12","conditions":"Rabies","enrollment":240}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":5,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["PVRV, VERORAB"],"phase":"marketed","status":"active","brandName":"Purified Verocell Rabies Vaccine","genericName":"Purified Verocell Rabies Vaccine","companyName":"Sanofi Pasteur, a Sanofi Company","companyId":"sanofi","modality":"Biologic","firstApprovalDate":"","aiSummary":"This vaccine stimulates the immune system to produce antibodies and cellular immunity against rabies virus by presenting inactivated viral antigens. Used for Rabies post-exposure prophylaxis (PEP) in previously unvaccinated individuals, Rabies pre-exposure prophylaxis (PrEP) in high-risk populations, Rabies post-exposure prophylaxis in previously vaccinated individuals.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}