{"id":"purethal-mites-50-000-aueq-ml","safety":{"commonSideEffects":[{"rate":null,"effect":"Oral pruritus"},{"rate":null,"effect":"Throat irritation"},{"rate":null,"effect":"Mouth edema"},{"rate":null,"effect":"Local allergic reactions at administration site"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This product contains a standardized extract of dust mite allergens (measured in AUeq/ml units) administered as sublingual immunotherapy. It works by inducing immune tolerance through repeated low-dose exposure, shifting the immune response from IgE-mediated (allergic) to IgG-mediated (protective) antibodies and promoting regulatory T cells. Over time, this reduces allergic symptoms and the need for symptomatic medications.","oneSentence":"PURETHAL Mites is an allergen immunotherapy that desensitizes the immune system to dust mite allergens through gradual exposure to standardized mite extract.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:54:15.029Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Allergic rhinitis and/or allergic asthma caused by dust mite allergens"}]},"trialDetails":[],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"PURETHAL Mites 50,000 AUeq/ml","genericName":"PURETHAL Mites 50,000 AUeq/ml","companyName":"HAL Allergy","companyId":"hal-allergy","modality":"Biologic","firstApprovalDate":"","aiSummary":"PURETHAL Mites is an allergen immunotherapy that desensitizes the immune system to dust mite allergens through gradual exposure to standardized mite extract. Used for Allergic rhinitis and/or allergic asthma caused by dust mite allergens.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":false,"score":3}}