{"id":"purethal-grasses-20-000-aum-ml","safety":{"commonSideEffects":[{"rate":null,"effect":"Local injection site reactions (erythema, swelling, pruritus)"},{"rate":null,"effect":"Systemic allergic reactions"},{"rate":null,"effect":"Anaphylaxis"}]},"_chembl":{"chemblId":"CHEMBL1732375","moleculeType":"Small molecule","molecularWeight":"369.34"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This product contains standardized grass pollen allergen extract (20,000 AUM/ml) used in allergen immunotherapy (AIT). It works by gradually exposing patients to increasing doses of grass allergens, which induces immune tolerance through shift toward regulatory T cells and IgG-blocking antibodies, reducing allergic symptoms upon natural grass pollen exposure.","oneSentence":"PURETHAL Grasses is an allergen extract that desensitizes the immune system to grass pollen allergens through repeated subcutaneous administration.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:03:20.389Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Allergic rhinitis and/or allergic asthma caused by grass pollen allergens"}]},"trialDetails":[{"nctId":"NCT01059266","phase":"PHASE4","title":"PURETHAL Grasses Rush Study","status":"COMPLETED","sponsor":"HAL Allergy","startDate":"2010-02","conditions":"Allergic Rhinitis, Allergic Rhinoconjunctivitis","enrollment":150}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"PURETHAL Grasses, 20.000 AUM/ml","genericName":"PURETHAL Grasses, 20.000 AUM/ml","companyName":"HAL Allergy","companyId":"hal-allergy","modality":"Small molecule","firstApprovalDate":"","aiSummary":"PURETHAL Grasses is an allergen extract that desensitizes the immune system to grass pollen allergens through repeated subcutaneous administration. Used for Allergic rhinitis and/or allergic asthma caused by grass pollen allergens.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}