{"id":"psyllium-orange","safety":{"commonSideEffects":[{"rate":null,"effect":"Bloating"},{"rate":null,"effect":"Flatulence"},{"rate":null,"effect":"Abdominal discomfort"},{"rate":null,"effect":"Allergic reactions (rare)"}]},"_chembl":{"chemblId":"CHEMBL4094858","moleculeType":"Small molecule","molecularWeight":"476.62"},"_dailymed":{"setId":"5ba85513-27a5-4f9e-9836-faf1d4c20980","title":"JBA COLLAGEN-BETHIN MOCKTAIL WITH PSYLLIUM FIBER CURCOUSIN (VITAMIN C,VITAMIN D3,VITAMIN E,NIACINAMCIDE,BIOTIN,ZINC,SELENIUM,MARINE COLLAGEN PEPTIDE,PSYLLIUM HUSK,ORANGE JUICE POWDER,CURCOUSIN,HYALURONIC ACID,ALOE VERA EXTRACT,CORDYCEPS EXTRACT,ELASTIN,FERMENTED BLACK SOYBEAN,FERMENTED BLACK RICE) POWDER [ADVANCED PHARMACEUTICAL SERVICES, INC. DBA AFFORDABLE QUALITY PHARMACEUTICALS]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Psyllium husk contains mucilage that forms a viscous gel when mixed with water, increasing fecal mass and promoting peristalsis. This mechanism helps normalize bowel movements in both constipation and diarrhea by regulating intestinal transit time. The orange flavoring is an organoleptic additive to improve palatability of the fiber supplement.","oneSentence":"Psyllium is a soluble dietary fiber that absorbs water in the gastrointestinal tract to increase stool bulk and promote bowel regularity.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T05:23:46.440Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Constipation relief"},{"name":"Bowel regularity maintenance"},{"name":"Irritable bowel syndrome symptom management"}]},"trialDetails":[{"nctId":"NCT05086185","phase":"","title":"Effect of Viscous Fiber on Postprandial Kalemic Response in Hemodialysis Patients","status":"COMPLETED","sponsor":"University of Nevada, Reno","startDate":"2021-06-29","conditions":"Hyperkalemia, Chronic Kidney Disease Requiring Chronic Dialysis","enrollment":7},{"nctId":"NCT05923723","phase":"NA","title":"Efficacy of a Dietary Intervention for the Treatment of Constipation in Institutionalized Older Adults. Medellín, 2023-2024.","status":"COMPLETED","sponsor":"CES University","startDate":"2024-03-15","conditions":"Constipation Chronic Idiopathic","enrollment":56},{"nctId":"NCT02810691","phase":"NA","title":"The Effect of Soluble Fiber to Reduce Post-prandial Glycemic Excursion in Adults With Cystic Fibrosis","status":"COMPLETED","sponsor":"Institut de Recherches Cliniques de Montreal","startDate":"2016-07","conditions":"Cystic Fibrosis-related Diabetes, Cystic Fibrosis","enrollment":14},{"nctId":"NCT02867917","phase":"NA","title":"Comparison of Taste and Palatability in Fiber Supplements","status":"COMPLETED","sponsor":"Amsterdam UMC, location VUmc","startDate":"2016-11","conditions":"Constipation","enrollment":100},{"nctId":"NCT01809925","phase":"NA","title":"Study of Psyllium 6.8 g Versus Placebo on Satiety in Healthy Volunteers","status":"COMPLETED","sponsor":"Procter and Gamble","startDate":"2013-03","conditions":"Hunger","enrollment":45}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":8,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Psyllium Orange","genericName":"Psyllium Orange","companyName":"Amsterdam UMC, location VUmc","companyId":"amsterdam-umc-location-vumc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Psyllium is a soluble dietary fiber that absorbs water in the gastrointestinal tract to increase stool bulk and promote bowel regularity. Used for Constipation relief, Bowel regularity maintenance, Irritable bowel syndrome symptom management.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}