{"id":"psyllium-husks","safety":{"commonSideEffects":[{"rate":null,"effect":"Bloating"},{"rate":null,"effect":"Flatulence"},{"rate":null,"effect":"Abdominal discomfort"},{"rate":null,"effect":"Allergic reactions (rare)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Psyllium is a soluble dietary fiber derived from the seeds of Plantago ovata. When ingested with water, it absorbs liquid and expands to create a gelatinous mass that stimulates peristalsis and facilitates passage through the gastrointestinal tract. It also acts as a prebiotic, feeding beneficial gut bacteria, and can help normalize cholesterol and blood glucose levels.","oneSentence":"Psyllium husks absorb water in the intestines to form a viscous gel that increases stool bulk and promotes bowel regularity.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:03:18.937Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Constipation"},{"name":"Irritable bowel syndrome (IBS)"},{"name":"Hypercholesterolemia (adjunctive)"},{"name":"Type 2 diabetes (adjunctive)"}]},"trialDetails":[{"nctId":"NCT06789471","phase":"NA","title":"The Effects of Psyllium Seed on Body Weight and Metabolic Syndrome Indicators in Patients with Schizophrenia","status":"COMPLETED","sponsor":"Ru-Shin Zhang","startDate":"2024-05-01","conditions":"Overweight and Obesity, Metabolic Cardiovascular Syndrome, Schizophrenia, Disorganized","enrollment":24},{"nctId":"NCT06492200","phase":"NA","title":"Impact of a High-fiber Diet on the Microbiome and Disease Activity in Patients With Rheumatoid Arthritis","status":"RECRUITING","sponsor":"Wuerzburg University Hospital","startDate":"2024-06-01","conditions":"Arthritis, Rheumatoid","enrollment":52},{"nctId":"NCT01251991","phase":"PHASE4","title":"Cholesterol Lowering Treatment With Psyllium Husks and Isolated Soy Protein in Hypercholesterolemia","status":"COMPLETED","sponsor":"Aalborg University Hospital","startDate":"2011-01","conditions":"Hypercholesterolemia","enrollment":41}],"_emaApprovals":[],"_faersSignals":[{"count":46,"reaction":"CONSTIPATION"},{"count":39,"reaction":"PAIN"},{"count":34,"reaction":"OFF LABEL USE"},{"count":28,"reaction":"FALL"},{"count":27,"reaction":"DRUG INEFFECTIVE"},{"count":27,"reaction":"FATIGUE"},{"count":27,"reaction":"HEADACHE"},{"count":26,"reaction":"HYPERTENSION"},{"count":26,"reaction":"ORTHOSTATIC HYPOTENSION"},{"count":25,"reaction":"HYPOTENSION"}],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Psyllium husks","genericName":"Psyllium husks","companyName":"Aalborg University Hospital","companyId":"aalborg-university-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Psyllium husks absorb water in the intestines to form a viscous gel that increases stool bulk and promotes bowel regularity. Used for Constipation, Irritable bowel syndrome (IBS), Hypercholesterolemia (adjunctive).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}