{"id":"psilocin","_chembl":null,"_dailymed":null,"_scrapedAt":"2026-03-28T03:00:05.504Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T11:12:32.382661+00:00","fieldsConflicting":0,"overallConfidence":0.95},"trialDetails":[{"nctId":"NCT06564818","phase":"PHASE3","title":"\"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder\"","status":"RECRUITING","sponsor":"Cybin IRL Limited","startDate":"2024-12-17","conditions":"Major Depressive Disorder","enrollment":220},{"nctId":"NCT07490353","phase":"PHASE1","title":"Elucidating the Relevance of the Psychedelic Experience to Psilocybin's Anti-Anhedonic Effects","status":"RECRUITING","sponsor":"Medical University of Vienna","startDate":"2025-11-01","conditions":"Depression - Major Depressive Disorder, Anhedonia","enrollment":85},{"nctId":"NCT06793397","phase":"PHASE3","title":"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder","status":"RECRUITING","sponsor":"Cybin IRL Limited","startDate":"2025-12-10","conditions":"Major Depressive Disorder (MDD), Depression in Adults, Depression - Major Depressive Disorder","enrollment":330},{"nctId":"NCT06605105","phase":"PHASE3","title":"Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)","status":"ENROLLING_BY_INVITATION","sponsor":"Cybin IRL Limited","startDate":"2025-07-18","conditions":"Major Depressive Disorder","enrollment":468},{"nctId":"NCT07275970","phase":"PHASE1","title":"Safety and Preliminary Efficacy of Organic Whole Psilocybin-Containing Mushrooms to Treat Patients Suffering From PTSD","status":"RECRUITING","sponsor":"Suzanne \"Sue\" Sisley MD","startDate":"2026-02-09","conditions":"PTSD","enrollment":24},{"nctId":"NCT07072728","phase":"PHASE2","title":"Psilocybin-Assisted Psychotherapy in Cancer Patients With Adjustment Disorder","status":"RECRUITING","sponsor":"Psyence Australia Pty Ltd","startDate":"2025-10-01","conditions":"Adjustment Disorder, Adjustment Disorder With Anxious Mood, Cancer","enrollment":87},{"nctId":"NCT04501653","phase":"EARLY_PHASE1","title":"Precision Functional Brain Mapping in Psilocybin","status":"COMPLETED","sponsor":"Washington University School of Medicine","startDate":"2021-06-01","conditions":"Psilocybin","enrollment":11},{"nctId":"NCT06820723","phase":"PHASE2","title":"A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety","status":"NOT_YET_RECRUITING","sponsor":"Ohio State University","startDate":"2025-11","conditions":"Depression, Anxiety, Major Depressive Disorder","enrollment":40},{"nctId":"NCT06746441","phase":"PHASE2","title":"Effect of Psilocybin Only and Psilocybin Assisted Cognitive Behavioral Therapy in the Management of Major Depressive Disorder and Associated Metabolic, Immune, Inflammatory, Neuroplasticity and Electrical Activity Markers","status":"COMPLETED","sponsor":"Khyber Medical University Peshawar","startDate":"2024-12-01","conditions":"Major Depressive Disorder","enrollment":60},{"nctId":"NCT05317689","phase":"PHASE1","title":"Comparing the Effects of Psilocin and Psilocybin in Healthy Adults","status":"ACTIVE_NOT_RECRUITING","sponsor":"University of California, San Francisco","startDate":"2022-05-26","conditions":"Healthy","enrollment":20},{"nctId":"NCT05434156","phase":"PHASE1, PHASE2","title":"ELE-101 Safety & Tolerability Study in Healthy Participants and Patients With Depression","status":"ACTIVE_NOT_RECRUITING","sponsor":"Eleusis Therapeutics","startDate":"2022-10-27","conditions":"Healthy Volunteers, Major Depressive Disorder, Depression","enrollment":84},{"nctId":"NCT04718792","phase":"PHASE2","title":"Psilocybin for Treatment of Alcohol Use Disorder: a Feasibility Study","status":"ACTIVE_NOT_RECRUITING","sponsor":"Anders Fink-Jensen, MD, DMSci","startDate":"2023-02-09","conditions":"Alcohol Use Disorder (AUD)","enrollment":10},{"nctId":"NCT06471959","phase":"PHASE1, PHASE2","title":"Psychedelic-assisted Group Program for First Responders","status":"RECRUITING","sponsor":"Empower Research Inc","startDate":"2025-01-01","conditions":"Psilocybin, Psychotherapy, Group","enrollment":32},{"nctId":"NCT06341426","phase":"PHASE2","title":"Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: Comparing One Versus Two Doses of Psilocybin","status":"RECRUITING","sponsor":"University Health Network, Toronto","startDate":"2024-02-05","conditions":"Major Depressive Disorder, Depression, Treatment-Resistant Depression","enrollment":92},{"nctId":"NCT05385783","phase":"PHASE1, PHASE2","title":"A Study of a Psilocybin Analog (CYB003) in Healthy Participants With and Without Major Depressive Disorder","status":"COMPLETED","sponsor":"Cybin IRL Limited","startDate":"2022-08-02","conditions":"Major Depressive Disorder","enrollment":57},{"nctId":"NCT06035900","phase":"PHASE1","title":"Evaluation of Safety, Rate and Extent of Absorption of Psilocin Mucate","status":"COMPLETED","sponsor":"Lobe Sciences Ltd.","startDate":"2023-06-21","conditions":"Side Effect of Drug","enrollment":10}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":400,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"PSILOCIN","genericName":"PSILOCIN","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"","enrichmentLevel":5,"visitCount":1,"trialStats":{"total":4,"withResults":0},"validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T11:12:32.382661+00:00","fieldsConflicting":0,"overallConfidence":0.95},"verificationStatus":"partial","dataCompleteness":{"mechanism":false,"indications":false,"safety":false,"trials":true,"score":1}}