{"id":"propatylnitrate","rwe":[],"tags":[{"label":"Vasodilators Organic Nitrates","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"C01DA07","category":"atc"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"etrynit","offLabel":[],"synonyms":["propatylnitrate","propatyl nitrate","etrynit","ettriol trinitrate"],"timeline":[],"approvals":[],"brandName":"Etrynit","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"Vasodilators Organic Nitrates","explanation":"Think of it like a valve in a hose. When the valve is open, water flows freely. In the case of Etrynit, the 'valve' is the blood vessel muscle. When nitric oxide is released, it opens the valve, allowing blood to flow more easily and reducing blood pressure.","oneSentence":"Etrynit works by releasing nitric oxide, which relaxes blood vessel muscles and causes blood vessels to dilate.","technicalDetail":"Etrynit exerts its effects through the release of nitric oxide, which activates guanylate cyclase, leading to an increase in cyclic guanosine monophosphate (cGMP) levels and subsequent relaxation of vascular smooth muscle."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2295","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=propatylnitrate","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:29:39.417523","biosimilars":[],"competitors":[{"drugName":"glyceryl trinitrate","drugSlug":"glyceryl-trinitrate","fdaApproval":"1981-05-28","relationship":"same-class"},{"drugName":"isosorbide dinitrate","drugSlug":"isosorbide-dinitrate","fdaApproval":"1968-01-16","genericCount":13,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"isosorbide mononitrate","drugSlug":"isosorbide-mononitrate","fdaApproval":"1991-12-30","genericCount":18,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"genericName":"propatylnitrate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"glyceryl-trinitrate","brandName":"glyceryl trinitrate","genericName":"glyceryl trinitrate","approvalYear":"1981","relationship":"same-class"},{"drugId":"isosorbide-dinitrate","brandName":"isosorbide dinitrate","genericName":"isosorbide dinitrate","approvalYear":"1968","relationship":"same-class"},{"drugId":"isosorbide-mononitrate","brandName":"isosorbide mononitrate","genericName":"isosorbide mononitrate","approvalYear":"1991","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"AJT2YN495R","CHEBI":"CHEBI:135104","INN_ID":"1236","UMLSCUI":"C0072168","ChEMBL_ID":"CHEMBL488280","KEGG_DRUG":"D05627","DRUGBANK_ID":"DB13255","PUBCHEM_CID":"66261","MESH_SUPPLEMENTAL_RECORD_UI":"C026352"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":4,"therapeuticAreas":["Hematology"],"atcClassification":{"source":"DrugCentral","atcCode":"C01DA07","allCodes":["C01DA07","C01DA57"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Etrynit is a small molecule medication with the synonyms ETRYNIT, ETT-N, ETTN, PROPATILNITRATO, PROPATYL NITRATE, and PROPATYL NITRATE. It is used as a nitrovasodilator to treat angina pectoris.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}