{"id":"prevention-of-venous-thromboembolism","safety":{"commonSideEffects":[{"rate":"null","effect":"Major bleeding"},{"rate":"null","effect":"Gastrointestinal bleeding"},{"rate":"null","effect":"Hemorrhage"}]},"_chembl":{"chemblId":"CHEMBL220050","moleculeType":"Small molecule","molecularWeight":"447.97"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"It does this by targeting and inhibiting the activity of Factor Xa, a key enzyme in the coagulation pathway. This leads to a reduction in the formation of thrombin, which is essential for blood clot formation. As a result, the risk of venous thromboembolism is decreased.","oneSentence":"This drug prevents the formation of blood clots in the veins by inhibiting the coagulation cascade.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:30:10.502Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of venous thromboembolism in patients undergoing major orthopedic surgery"}]},"trialDetails":[{"nctId":"NCT07493304","phase":"PHASE3","title":"Treatment and Secondary Prevention of Venous Thromboembolism (VTE) in Adult Participants With Solid and Hematologic Cancers","status":"NOT_YET_RECRUITING","sponsor":"Regeneron Pharmaceuticals","startDate":"2026-04-07","conditions":"Venous Thromboembolism (VTE)","enrollment":1600},{"nctId":"NCT06753786","phase":"NA","title":"Timing of Venous Thromboembolism Prophylaxis in Patients With Hypertensive Intracerebral Hemorrhage","status":"RECRUITING","sponsor":"Pirogov Russian National Research Medical University","startDate":"2024-10-21","conditions":"Venous Thromboembolism, Pulmonary Embolism, Intracerebral Hemorrhage","enrollment":200},{"nctId":"NCT05198960","phase":"PHASE3","title":"AVAJAK: Apixaban/Rivaroxaban Versus Aspirin for Primary Prevention of Thrombo-embolic Complications in JAK2V617F-positive Myeloproliferative Neoplasms","status":"RECRUITING","sponsor":"University Hospital, Brest","startDate":"2022-07-13","conditions":"Polycythemia Vera, Essential Thrombocythemia, Prefibrotic/Early Primary Myelofibrosis","enrollment":1308},{"nctId":"NCT07410117","phase":"PHASE3","title":"REGN7508 in Adult Participants for Prevention of Cancer-Associated Thrombosis","status":"RECRUITING","sponsor":"Regeneron Pharmaceuticals","startDate":"2026-03-09","conditions":"Cancer-Associated Thrombosis (CAT)","enrollment":860},{"nctId":"NCT07213778","phase":"PHASE3","title":"REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants","status":"RECRUITING","sponsor":"Regeneron Pharmaceuticals","startDate":"2025-11-24","conditions":"Symptomatic Venous Thromboembolism (VTE)","enrollment":2000},{"nctId":"NCT07464808","phase":"NA","title":"Utilizing Anti-Factor Xa as a Predictive Tool for Optimizing Outcome in Burn Patients' Management","status":"RECRUITING","sponsor":"Ain Shams University","startDate":"2025-11-28","conditions":"Venous Thromboembolic Event","enrollment":25},{"nctId":"NCT06825416","phase":"PHASE3","title":"A Clinical Study of SHR-2004 Injection in Preventing Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty","status":"ACTIVE_NOT_RECRUITING","sponsor":"Beijing Suncadia Pharmaceuticals Co., Ltd","startDate":"2025-03-16","conditions":"Prevention of Arterial and Venous Thrombosis","enrollment":1166},{"nctId":"NCT07015905","phase":"PHASE3","title":"REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults","status":"RECRUITING","sponsor":"Regeneron Pharmaceuticals","startDate":"2025-06-25","conditions":"Venous Thromboembolism (VTE)","enrollment":2000},{"nctId":"NCT07455253","phase":"","title":"Effectiveness and Cost-effectiveness of VTE Prevention Strategies in Gynecological Surgery","status":"ACTIVE_NOT_RECRUITING","sponsor":"Affiliated Hospital of Nantong University","startDate":"2025-11-10","conditions":"Venous Thromboembolism, Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE)","enrollment":234},{"nctId":"NCT07454707","phase":"PHASE3","title":"Testing a New Treatment Strategy to Improve Secondary Stroke Prevention for Older Adults: The STROKE75+ Trial","status":"NOT_YET_RECRUITING","sponsor":"Sunnybrook Health Sciences Centre","startDate":"2026-04","conditions":"Stroke, Ischemic","enrollment":1204},{"nctId":"NCT06454630","phase":"PHASE2","title":"A Trial to Learn How Well REGN7508 Works for Preventing Blood Clots After a Knee Replacement in Adult Participants","status":"COMPLETED","sponsor":"Regeneron Pharmaceuticals","startDate":"2024-06-27","conditions":"Venous Thromboembolism","enrollment":179},{"nctId":"NCT03728166","phase":"NA","title":"Computerized Decision Support for Prevention of VTE in Hospitalized Medical Patients Across the Continuum of Care (DC-eALERT)","status":"RECRUITING","sponsor":"Brigham and Women's Hospital","startDate":"2019-02-01","conditions":"Venous Thromboembolism","enrollment":400},{"nctId":"NCT06087952","phase":"NA","title":"Leiden Thrombosis Recurrence Risk Prevention","status":"ACTIVE_NOT_RECRUITING","sponsor":"Leiden University Medical Center","startDate":"2021-06-18","conditions":"Venous Thromboembolism, Venous Thromboses, Pulmonary Embolism","enrollment":608},{"nctId":"NCT06939803","phase":"NA","title":"AI-driven Clinical Decision Support to Reduce Hospital-Acquired Venous Thromboembolism: Study Protocol for the VTE-AI Randomized Trial.","status":"RECRUITING","sponsor":"Vanderbilt University Medical Center","startDate":"2025-12-17","conditions":"Venothromboembolism","enrollment":2236},{"nctId":"NCT07401394","phase":"NA","title":"BAR-TAX - Tranexamic Acid in Bariatric Surgery.","status":"ACTIVE_NOT_RECRUITING","sponsor":"Santa Maria Hospital - GVM Care & Research","startDate":"2025-12-01","conditions":"Bariatric Surgery, Bariatric Patients, Bariatric Surgery Complications","enrollment":1000},{"nctId":"NCT07404436","phase":"PHASE4","title":"Rivaroxaban in Idiopathic Membranous Nephropathy","status":"RECRUITING","sponsor":"Beijing Friendship Hospital","startDate":"2024-01-05","conditions":"Idiopathic Membranous Nephropathy","enrollment":134},{"nctId":"NCT06243510","phase":"NA","title":"Comparison of Apixaban Versus Enoxaparin","status":"ENROLLING_BY_INVITATION","sponsor":"Abramson Cancer Center at Penn Medicine","startDate":"2023-11-24","conditions":"Bladder Cancer","enrollment":90},{"nctId":"NCT04273607","phase":"PHASE2, PHASE3","title":"Anticoagulation-free VV ECMO for Acute Respiratory Failure","status":"RECRUITING","sponsor":"Damian Ratano","startDate":"2022-09-01","conditions":"Extracorporeal Membrane Oxygenation Complication","enrollment":40},{"nctId":"NCT07347652","phase":"NA","title":"This Research Proposal Focuses on Evaluating the Effectiveness of a Nursing Care Protocol in Preventing Deep Vein Thrombosis (DVT) in Patients Undergoing On-pump Cardiac Surgery. The Study Will Include an Intervention Group That Receives the Nursing Protocol and a Control Group That Receives Routine","status":"ACTIVE_NOT_RECRUITING","sponsor":"Near East University, Turkey","startDate":"2025-06-14","conditions":"On-pump Cardiac Surgery - Prevention - Intervention - Experimental Group - Control Group - Incidence - Complications, DVT - Deep Vein Thrombosis, DVT Prophylaxis","enrollment":67},{"nctId":"NCT06299111","phase":"PHASE2","title":"A Trial to Learn How Well REGN9933 and REGN7508 Work for Preventing Blood Clots, and How Safe They Are, in Adults Who Have a Peripherally Inserted Central Catheter (PICC)","status":"ACTIVE_NOT_RECRUITING","sponsor":"Regeneron Pharmaceuticals","startDate":"2024-09-20","conditions":"Venous Thromboembolism","enrollment":195},{"nctId":"NCT07287007","phase":"NA","title":"Evaluating the Hemodynamic Performance of the VenAir Sequential Compression System","status":"RECRUITING","sponsor":"Wellell Inc. Taiwan","startDate":"2025-10-06","conditions":"No Condition, Healthy Individuals, No Conditions, Aged 20-64","enrollment":105},{"nctId":"NCT05089227","phase":"PHASE2","title":"Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Autoimmune Hemolytic Anemia: a Prospective, Phase II, Randomized, Multicenter Study","status":"RECRUITING","sponsor":"Centre Hospitalier Universitaire Dijon","startDate":"2022-02-03","conditions":"Prolonged Anticoagulation, Venous Thromboembolic Disease, Autoimmune Hemolytic Anemia","enrollment":72},{"nctId":"NCT00740844","phase":"PHASE3","title":"Efficacy of Intermittent Pneumatic Compression (IPC) on Venous Thromboembolism Incidence in Intensive Care Unit (ICU) Patients With High Bleeding Risk","status":"COMPLETED","sponsor":"University Hospital, Brest","startDate":"2007-11","conditions":"High Bleeding Risk, Hemorrhage","enrollment":408},{"nctId":"NCT05628207","phase":"","title":"Evaluation of the SCALED (SCaling AcceptabLE cDs)","status":"RECRUITING","sponsor":"University of Minnesota","startDate":"2023-05-16","conditions":"Traumatic Brain Injury, Venous Thromboembolism","enrollment":15000},{"nctId":"NCT02810704","phase":"PHASE4","title":"Comparative Effectiveness of Pulmonary Embolism Prevention After Hip and Knee Replacement","status":"COMPLETED","sponsor":"Dartmouth-Hitchcock Medical Center","startDate":"2016-12","conditions":"Pulmonary Embolism, Venous Thrombosis","enrollment":18883},{"nctId":"NCT07243080","phase":"PHASE4","title":"Comparative Efficacy of Rivaroxaban and Enoxaparin in Post-Laparotomy DVT Prevention","status":"RECRUITING","sponsor":"Mayo Hospital Lahore","startDate":"2025-10-10","conditions":"Deep Venous Thromboses, Laparotomy Patients","enrollment":212},{"nctId":"NCT04168203","phase":"PHASE4","title":"Extended-Duration Low-Intensity Apixaban to Prevent Recurrence in High-Risk Patients With Provoked Venous Thromboembolism","status":"COMPLETED","sponsor":"Brigham and Women's Hospital","startDate":"2021-03-01","conditions":"Deep Vein Thrombosis, Pulmonary Embolism, Venous Thromboembolism","enrollment":600},{"nctId":"NCT07228663","phase":"PHASE3","title":"Hip Fracture Surgery Arterial and Venous Thrombotic Events Prevention","status":"NOT_YET_RECRUITING","sponsor":"McMaster University","startDate":"2025-12-01","conditions":"Hip Fracture Surgery, Cardiovascular Prevention, Venous Thromboembolism (VTE)","enrollment":100},{"nctId":"NCT04684212","phase":"NA","title":"Can the Lambre Device Occlude IRRegular And Large Appendages in Patients With Non-Valvular AF","status":"WITHDRAWN","sponsor":"Brian O'Neill MD","startDate":"2024-06-01","conditions":"Atrial Fibrillation, Left Atrial Appendage Thrombosis, CVA","enrollment":""},{"nctId":"NCT07196020","phase":"","title":"Prediction of Venous Thrombosis During chemotherapy-the PINPOINT Study","status":"NOT_YET_RECRUITING","sponsor":"University of Dublin, Trinity College","startDate":"2025-10-01","conditions":"Venous Thromboembolism, Cancer","enrollment":380},{"nctId":"NCT05208216","phase":"NA","title":"Neuromuscular Stimulation Versus Intermittent Compression for Venous Thromboembolism Prophylaxis in Critical Care","status":"COMPLETED","sponsor":"Manchester University NHS Foundation Trust","startDate":"2022-11-01","conditions":"Critical Illness, Sepsis, Acute Illness","enrollment":40},{"nctId":"NCT04211181","phase":"NA","title":"CHIPs-VTE Study in Hospitalized Patients to Prevent Hospital-Acquired Venous Thromboembolism","status":"RECRUITING","sponsor":"China-Japan Friendship Hospital","startDate":"2025-08-01","conditions":"Venous Thromboembolic Disease, Pulmonary Embolism, Venous Thromboembolism","enrollment":5800},{"nctId":"NCT06180889","phase":"PHASE2","title":"Factor XI inhibiTion for the Prevention of Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty","status":"ACTIVE_NOT_RECRUITING","sponsor":"Suzhou Alphamab Co., Ltd.","startDate":"2023-12-20","conditions":"Knee Arthroplasty, Total","enrollment":241},{"nctId":"NCT06581965","phase":"PHASE4","title":"inDividual, Targeted thrombosIS Prophylaxis Versus the Standard 'One Size Fits All' Approach in Patients Undergoing Total hIp or Total kNee replaCemenT","status":"RECRUITING","sponsor":"Leiden University Medical Center","startDate":"2024-11-11","conditions":"Venous Thromboembolism, Venous Thromboses, Pulmonary Embolism","enrollment":10078},{"nctId":"NCT05618808","phase":"PHASE2","title":"A Trial to Learn How Well REGN9933 Works for Preventing Blood Clots After Knee Replacement Surgery in Adult Participants","status":"COMPLETED","sponsor":"Regeneron Pharmaceuticals","startDate":"2023-05-24","conditions":"Venous Thromboembolism","enrollment":373},{"nctId":"NCT05625932","phase":"PHASE3","title":"TINzaparin Prophylaxis in Patients With Metastatic Colorectal Cancer","status":"COMPLETED","sponsor":"Galician Research Group on Digestive Tumors","startDate":"2023-03-02","conditions":"Colorectal Cancer Metastatic, Thromboembolism","enrollment":232},{"nctId":"NCT02066454","phase":"PHASE3","title":"Evaluation of the Use of Apixaban in Prevnetion of Thromboembolic Disease in Patients With Myeloma Trated With iMiDs","status":"COMPLETED","sponsor":"University Hospital, Grenoble","startDate":"2014-06-05","conditions":"Myeloma, Venous Thromboembolism","enrollment":108},{"nctId":"NCT06451003","phase":"NA","title":"Intervention to Improve Utilization of Extended Venous Thromboembolism Prophylaxis After Cancer Surgery","status":"RECRUITING","sponsor":"Medical University of South Carolina","startDate":"2024-07-01","conditions":"Venous Thromboembolism, Pulmonary Embolism, Deep Vein Thrombosis","enrollment":30},{"nctId":"NCT06956339","phase":"NA","title":"Cross Bracing Protocol Versus Surgery for Acute Anterior Cruciate Ligament Rupture","status":"RECRUITING","sponsor":"University of Melbourne","startDate":"2025-08","conditions":"Anterior Cruciate Ligament Rupture","enrollment":180},{"nctId":"NCT05920343","phase":"PHASE2, PHASE3","title":"VTE Prevention With Rivaroxaban in Genitourinary Cancer Patients Receiving Systemic Therapy","status":"RECRUITING","sponsor":"Ottawa Hospital Research Institute","startDate":"2024-11-04","conditions":"Venous Thromboembolism, Urologic Cancer","enrollment":120},{"nctId":"NCT04924322","phase":"PHASE2, PHASE3","title":"Catheter-Related Early Thromboprophylaxis With Enoxaparin Studies","status":"RECRUITING","sponsor":"Yale University","startDate":"2022-05-11","conditions":"Deep Venous Thrombosis","enrollment":258},{"nctId":"NCT06350331","phase":"NA","title":"Smart Technology Facilitated Patient-centered Venous Thromboembolism Management","status":"ENROLLING_BY_INVITATION","sponsor":"Navy General Hospital, Beijing","startDate":"2024-08-17","conditions":"Venous Thromboembolism, Digital Health, Health Education","enrollment":256},{"nctId":"NCT06382038","phase":"NA","title":"Smart Technology Facilitated Patient-centered Care for Patients With Pulmonary Thromboembolism","status":"NOT_YET_RECRUITING","sponsor":"Navy General Hospital, Beijing","startDate":"2025-10-08","conditions":"Venous Thromboembolism, Pulmonary Thromboembolisms, Digital Health","enrollment":2972},{"nctId":"NCT06603870","phase":"PHASE4","title":"Secondary Prevention of VTE in Patients With Cancer and Catheter-Related Upper Extremity Deep Vein Thrombosis","status":"RECRUITING","sponsor":"Ottawa Hospital Research Institute","startDate":"2024-12-19","conditions":"Venous Thromboembolism, Cancer, Upper Extremity Deep Vein Thrombosis","enrollment":330},{"nctId":"NCT06523959","phase":"PHASE4","title":"Avoiding Risks of Thrombosis and Bleeding in Surgery (ARTS) Trial","status":"RECRUITING","sponsor":"Clinical Urology and Epidemiology Working Group","startDate":"2024-06-06","conditions":"Venous Thromboembolism, Bleeding","enrollment":5436},{"nctId":"NCT06845423","phase":"PHASE4","title":"Prevention of Postpartum Venous Thromboembolism in Women at Intermediate Risk","status":"RECRUITING","sponsor":"University Hospital, Brest","startDate":"2025-05-16","conditions":"Venous Thromboembolism (VTE), Post Partum Women","enrollment":2400},{"nctId":"NCT06963320","phase":"PHASE2","title":"Phase II Clinical Study of H001 Capsule in the Prevention of Venous Thromboembolism After Total Knee Arthroplasty","status":"RECRUITING","sponsor":"Livzon Pharmaceutical Group Inc.","startDate":"2025-01-20","conditions":"Circulatory Disease","enrollment":320},{"nctId":"NCT06689241","phase":"NA","title":"Rivaroxaban Versus Enoxaparin for Prophylaxis of Venous Thromboembolism in Bariatric Surgery","status":"RECRUITING","sponsor":"Alexandria University","startDate":"2024-10-01","conditions":"Morbid Obesity, Bariatric Surgery Candidate","enrollment":162},{"nctId":"NCT05627375","phase":"PHASE3","title":"Best Antithrombotic Therapy in Patients With Acute Venous ThromboEmbolism While Taking Antiplatelets","status":"RECRUITING","sponsor":"Centre Hospitalier Universitaire de Saint Etienne","startDate":"2023-08-16","conditions":"Venous Thromboembolic Disease","enrollment":1400},{"nctId":"NCT05476913","phase":"NA","title":"GEKO Venous Thromboembolism Prevention Study","status":"RECRUITING","sponsor":"Firstkind Ltd","startDate":"2023-07-06","conditions":"Stroke, Acute, Venous Thromboembolism, Deep Vein Thrombosis","enrollment":1200},{"nctId":"NCT06418633","phase":"NA","title":"Variations in the Hemostatic System Induced by a Standardized Walking Test","status":"RECRUITING","sponsor":"Centre Hospitalier Universitaire de Nīmes","startDate":"2025-02-11","conditions":"Venous Thromboembolism","enrollment":94},{"nctId":"NCT00967447","phase":"","title":"Study to Evaluate the Safety and Efficacy of Pradaxar for the Prevention of Venous Thromboembolism in the Mexican Population Undergoing Elective Total Hip or Knee Replacement Surgery","status":"TERMINATED","sponsor":"Boehringer Ingelheim","startDate":"2009-02-01","conditions":"Thromboembolism, Arthroplasty, Replacement, Hip","enrollment":2},{"nctId":"NCT05752461","phase":"PHASE2","title":"SHR-2004 for the Prevention of Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty","status":"COMPLETED","sponsor":"Beijing Suncadia Pharmaceuticals Co., Ltd","startDate":"2023-04-12","conditions":"Prevention of Venous Thromboembolism After Knee Arthroplasty","enrollment":353},{"nctId":"NCT06611319","phase":"PHASE3","title":"ENhanced Recovery and ABbreviated LEngth of Anticoagulation for Thromboprophylaxis After Primary Hip Arthroplasty","status":"RECRUITING","sponsor":"Prof. Stavros Konstantinides, MD","startDate":"2024-11-26","conditions":"Hip Arthroplasty, Total, Prevention of Venous Thromboembolism","enrollment":2932},{"nctId":"NCT04710732","phase":"PHASE4","title":"Individual Dose Adjustment of Low-molecular-weight-heparin by Thromodynamics Test.","status":"TERMINATED","sponsor":"Pirogov Russian National Research Medical University","startDate":"2021-03-01","conditions":"Venous Thromboembolism","enrollment":9},{"nctId":"NCT05396157","phase":"","title":"Venous Thromboembolism in Hematologic Malignancy and Hematopoietic Cell Transplant Patients: a Retrospective Study","status":"ACTIVE_NOT_RECRUITING","sponsor":"Mount Sinai Hospital, Canada","startDate":"2021-11-01","conditions":"Thrombosis, Venous, Bleeding Hemorrhage, Venous Thromboembolic Disease","enrollment":813},{"nctId":"NCT03522259","phase":"PHASE2","title":"Rivaroxaban as Thrombosis Prophylaxis in Bariatric Surgery","status":"COMPLETED","sponsor":"Insel Gruppe AG, University Hospital Bern","startDate":"2018-07-19","conditions":"Bariatric Surgery","enrollment":272},{"nctId":"NCT06606275","phase":"","title":"The Safety and Effectiveness of Warfarin Vs Apixaban in Patients with NVAF/ VTE and ESKD on Dialysis","status":"COMPLETED","sponsor":"Abu Dhabi Health Services Company","startDate":"2024-01-01","conditions":"End-Stage Kidney Disease (ESKD), Non-valvular Atrial Fibrillation (NVAF), Venous Thromboembolism (VTE)","enrollment":67},{"nctId":"NCT05819112","phase":"","title":"A Comparison of Extended Versus Conventional Duration of Enoxaparin Prophylaxis (i.e., Preventive Treatment) for Venous Thromboembolism (VTE, i.e., Blood Clots in the Veins) and Bleeding Event Risk in a Population With Acute Medical Illness","status":"TERMINATED","sponsor":"Sanofi","startDate":"2023-04-25","conditions":"Venous Thromboembolism","enrollment":14799},{"nctId":"NCT05819125","phase":"","title":"Comparison of the Risk of Venous Thromboembolism (i.e., Blood Clots in the Veins) and Bleeding Events in a Population of Obese Patients Receiving Higher-Dose or Extended-Duration Versus Conventional-Dose or Conventional-Duration of Prophylaxis (i.e., Preventive Treatment) With Enoxaparin","status":"TERMINATED","sponsor":"Sanofi","startDate":"2023-04-25","conditions":"Venous Thromboembolism","enrollment":21000},{"nctId":"NCT06662253","phase":"PHASE2, PHASE3","title":"Anti-Xa Guided Dosing of Low Molecular Weight Heparin for Prevention of Venous Thromboembolism Following Traumatic Injury: a Multicentre Pilot Randomized Trial","status":"NOT_YET_RECRUITING","sponsor":"Alexandre Tran","startDate":"2025-01","conditions":"Venous Thromboembolism (VTE), Trauma Related Injuries","enrollment":150},{"nctId":"NCT03559114","phase":"PHASE3","title":"PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury (PROTEST)","status":"RECRUITING","sponsor":"Sunnybrook Health Sciences Centre","startDate":"2018-07-19","conditions":"Traumatic Brain Injury","enrollment":1100},{"nctId":"NCT04257487","phase":"PHASE3","title":"Sulodexide, VESSEL®, for the Prevention of Recurrent Venous Thromboembolism (The Jason Study)","status":"RECRUITING","sponsor":"Arianna Anticoagulazione Foundation","startDate":"2020-12-21","conditions":"Venous Thromboembolism, Anticoagulant, Elderly","enrollment":1455},{"nctId":"NCT06513481","phase":"","title":"A Study of Enhancing Drug Prophylaxis of Venous Thromboembolism in Chinese Colorectal Cancer Surgery","status":"NOT_YET_RECRUITING","sponsor":"RenJi Hospital","startDate":"2024-07-16","conditions":"Colorectal Cancer","enrollment":914},{"nctId":"NCT06350344","phase":"NA","title":"Smart Technology Facilitated Patient-centered Venous Thromboembolism Management","status":"NOT_YET_RECRUITING","sponsor":"Navy General Hospital, Beijing","startDate":"2024-11-01","conditions":"Venous Thromboembolism, Digital Health, Health Education","enrollment":2353},{"nctId":"NCT05536791","phase":"","title":"A Study in Europe Based on Medical Records That Looks at the Safety of Dabigatran in Children Below 2 Years of Age Who Have Had a Blood Clot and Are at Risk of Developing Another Blood Clot","status":"WITHDRAWN","sponsor":"Boehringer Ingelheim","startDate":"2022-11-24","conditions":"Venous Thromboembolism","enrollment":""},{"nctId":"NCT06443905","phase":"","title":"Xueshuantong Injection (Lyophilized) in the Prevention of Venous Thromboembolism (VTE) in Hospitalized Patients","status":"ACTIVE_NOT_RECRUITING","sponsor":"China-Japan Friendship Hospital","startDate":"2023-08-01","conditions":"Venous Thromboembolism (VTE), Thromboembolism","enrollment":21600},{"nctId":"NCT02984384","phase":"PHASE3","title":"PREVENTion of Clot in Orthopaedic Trauma","status":"COMPLETED","sponsor":"Major Extremity Trauma Research Consortium","startDate":"2017-04-24","conditions":"Blood Clot, Trauma","enrollment":12424},{"nctId":"NCT06353373","phase":"","title":"Smart Technology Facilitated Venous Thromboembolism Prophylaxis Based on Bundled Evidence-based Prevention Strategies","status":"NOT_YET_RECRUITING","sponsor":"Navy General Hospital, Beijing","startDate":"2024-09-01","conditions":"Venous Thromboembolism, Clinical Decision Support Systems, Digital Health","enrollment":15626},{"nctId":"NCT05347550","phase":"NA","title":"Examining the Benefit of Graduated Compression Stockings in the Prevention of vEnous Thromboembolism in Low-risk Surgical Patients","status":"RECRUITING","sponsor":"Imperial College London","startDate":"2022-09-08","conditions":"Venous Thromboembolism","enrollment":21472},{"nctId":"NCT06302478","phase":"NA","title":"5E Program for Preventing Venous Thromboembolism in Patients With Spinal Cord Disorders","status":"RECRUITING","sponsor":"Khon Kaen University","startDate":"2024-03-12","conditions":"Venous Thromboembolism, Spinal Cord Diseases, Spinal Cord Injuries","enrollment":42},{"nctId":"NCT04075240","phase":"PHASE3","title":"VTE Prevention Following Total Hip and Knee Arthroplasty","status":"RECRUITING","sponsor":"Sudeep Shivakumar","startDate":"2021-02-04","conditions":"Venous Thromboembolism","enrollment":5400},{"nctId":"NCT06196918","phase":"NA","title":"Efficacy and Safety of Rivaroxaban in the Prevention of Venous Thromboembolism in Glioma Patients","status":"UNKNOWN","sponsor":"Nanfang Hospital, Southern Medical University","startDate":"2023-11-01","conditions":"Glioma, Malignant","enrollment":320},{"nctId":"NCT05143567","phase":"NA","title":"Hemostasis and Inflammation in COVID-19 Patients With Venous and Arterial Thrombotic Complications","status":"COMPLETED","sponsor":"Ryazan State Medical University","startDate":"2021-11-01","conditions":"Venous Thromboembolism, covid19, Thrombosis","enrollment":150},{"nctId":"NCT02742623","phase":"","title":"A Non-interventional Study on Xarelto for Treatment of Venous Thromboembolism (VTE) and Prevention of Recurrent VTE in Patients With Active Cancer","status":"COMPLETED","sponsor":"Bayer","startDate":"2016-10-11","conditions":"Venous Thrombosis and Pulmonary Embolism","enrollment":528},{"nctId":"NCT06025162","phase":"","title":"Evaluation of Chemical Venous Thromboembolism Prophylaxis in Trauma","status":"UNKNOWN","sponsor":"Methodist Health System","startDate":"2023-07-21","conditions":"Thromboembolism, Venous","enrollment":100},{"nctId":"NCT04373707","phase":"PHASE4","title":"Weight-Adjusted vs Fixed Low Doses of Low Molecular Weight Heparin For Venous Thromboembolism Prevention in COVID-19","status":"COMPLETED","sponsor":"Central Hospital, Nancy, France","startDate":"2020-05-13","conditions":"COVID, Thrombosis, Pulmonary Embolism","enrollment":1000},{"nctId":"NCT01583218","phase":"PHASE3","title":"Acute Medically Ill VTE Prevention With Extended Duration Betrixaban Study (The APEX Study)","status":"COMPLETED","sponsor":"Portola Pharmaceuticals","startDate":"2012-03","conditions":"Venous Thromboembolism (VTE)","enrollment":7513},{"nctId":"NCT00375609","phase":"PHASE2","title":"Factor Xa Inhibitor, PRT054021, Against Enoxaparin for the Prevention of Venous Thromboembolic Events (EXPERT)","status":"COMPLETED","sponsor":"Portola Pharmaceuticals","startDate":"2006-05","conditions":"Thromboembolism","enrollment":215},{"nctId":"NCT05969951","phase":"","title":"VTE Risk Prevention System Based on Big Data Analysis and Multimodule System","status":"RECRUITING","sponsor":"Shengjing Hospital","startDate":"2021-04-14","conditions":"Recruiting","enrollment":100000},{"nctId":"NCT05382481","phase":"NA","title":"Anti Xa Monitoring Low Molecular Weight Heparin on Prevention of Venous Thromboembolism","status":"UNKNOWN","sponsor":"Xuanwu Hospital, Beijing","startDate":"2022-05-16","conditions":"Venous Thromboembolism","enrollment":858},{"nctId":"NCT03367364","phase":"NA","title":"Patient Education Bundle vs. Nurses Feedback and Coaching to Prevent Missed Doses of VTE Prophylaxis","status":"COMPLETED","sponsor":"Johns Hopkins University","startDate":"2018-01-01","conditions":"Venous Thrombosis (Disorder)","enrollment":9657},{"nctId":"NCT04558892","phase":"PHASE2, PHASE3","title":"Anti-Xa Activity of Enoxaparin for Prevention of Venous Thromboembolism in Severe Nephrotic Syndrome.","status":"TERMINATED","sponsor":"Military Institute od Medicine National Research Institute","startDate":"2015-10-01","conditions":"Nephrotic Syndrome","enrollment":65},{"nctId":"NCT05237726","phase":"NA","title":"Efficacy and Safety for Different Regimen of VTE Pharmacoprophylaxis Among Severely Burn Patients","status":"COMPLETED","sponsor":"King Abdullah International Medical Research Center","startDate":"2020-04-05","conditions":"Burns","enrollment":20},{"nctId":"NCT03090880","phase":"PHASE3","title":"Prophylaxis of Venous Thromboembolism in Advanced Lung Cancer (PROVE)","status":"TERMINATED","sponsor":"Assistance Publique - Hôpitaux de Paris","startDate":"2018-09-14","conditions":"Venous Thromboembolism, Lung Neoplasm","enrollment":59},{"nctId":"NCT02067182","phase":"PHASE4","title":"Prevention of Silent Cerebral Thromboembolism by Oral Anticoagulation With Dabigatran After Pulmonary Vein Isolation for Atrial Fibrillation","status":"COMPLETED","sponsor":"Georg Nickenig","startDate":"2015-08","conditions":"Atrial Fibrillation, Cardioembolic Events, Oral Anticoagulation","enrollment":200},{"nctId":"NCT04352439","phase":"PHASE4","title":"Aspirin for Prevention of Venous Thromboembolism Among Ovarian Cancer Patients Receiving Neoadjuvant Chemotherapy","status":"COMPLETED","sponsor":"Duke University","startDate":"2020-08-08","conditions":"Venous Thromboembolism, Ovarian Cancer","enrollment":19},{"nctId":"NCT00789399","phase":"NA","title":"A Study of the Efficacy of Preventive Dosing of Fondaparinux Sodium Versus Placebo for the Prevention of Venous Thromboembolism (VTE) in Patients Undergoing Coronary Bypass Surgery Receiving Routine Mechanical Prophylaxis","status":"TERMINATED","sponsor":"Prairie Education and Research Cooperative","startDate":"2009-11-19","conditions":"Deep Vein Thrombosis, Coronary Artery Bypass Surgery, Venous Thromboembolism","enrollment":78},{"nctId":"NCT01935414","phase":"NA","title":"Geko Neuromuscular Stimulator vs Thromboembolism Deterrent Stockings (TEDS): DVT Prevention Study","status":"COMPLETED","sponsor":"Firstkind Ltd","startDate":"2013-08","conditions":"Deep Vein Thrombosis","enrollment":72},{"nctId":"NCT02379806","phase":"PHASE3","title":"The SYMPTOMS - SYstematic Elderly Medical Patients Thromboprophylaxis: Efficacy on Symptomatic OutcoMeS - Study","status":"COMPLETED","sponsor":"University Hospital, Brest","startDate":"2015-09-03","conditions":"Venous Thromboembolism","enrollment":2560},{"nctId":"NCT05189002","phase":"PHASE2","title":"A Study to Evaluate Dimolegin in Prevention of Thromboembolic Complications During Knee Replacement","status":"UNKNOWN","sponsor":"PharmaDiall Ltd.","startDate":"2019-05-31","conditions":"Venous Thromboembolism","enrollment":240},{"nctId":"NCT04444804","phase":"","title":"Study to Compare the Effectiveness of Rivaroxaban (Xarelto) Versus Low-molecular-weight Heparin (LMWH) and Phenprocoumon for the Treatment and Secondary Prevention of Venous Thromboembolism in Routine Clinical Practice in Germany","status":"COMPLETED","sponsor":"Bayer","startDate":"2020-07-31","conditions":"Venous Thromboembolism","enrollment":22153},{"nctId":"NCT05330832","phase":"","title":"Covid-19 Associated Coagulopathy Predicted by Thrombodynamic Markers (CoViTro-I)","status":"UNKNOWN","sponsor":"Federal Research Institute of Pediatric Hematology, Oncology and Immunology","startDate":"2020-04-01","conditions":"Coronavirus Disease 2019","enrollment":2200},{"nctId":"NCT00493896","phase":"PHASE3","title":"Safety of Fondaparinux as Routine VTE Prophylaxis in Medical ICU Patients","status":"TERMINATED","sponsor":"Eastern Virginia Medical School","startDate":"2007-07","conditions":"Venous Thromboembolism","enrollment":27},{"nctId":"NCT02502396","phase":"","title":"Rivaroxaban Utilization for Treatment and Prevention of Thromboembolism in Cancer Patients: Experience at a Comprehensive Cancer Center","status":"COMPLETED","sponsor":"M.D. Anderson Cancer Center","startDate":"2015-09-28","conditions":"Cancer, Deep-vein Thrombosis of the Lower and Upper Extremities, Pulmonary Embolism","enrollment":265},{"nctId":"NCT02369653","phase":"PHASE3","title":"A Study of the Safety and Effectiveness of Apixaban in Preventing Blood Clots in Children With Leukemia Who Have a Central Venous Catheter and Are Treated With Asparaginase","status":"COMPLETED","sponsor":"Bristol-Myers Squibb","startDate":"2015-10-22","conditions":"Lymphoma, Acute Lymphoblastic Leukemia","enrollment":512},{"nctId":"NCT02836457","phase":"","title":"ELIQUIS (APIXABAN) Regulatory Post-Marketing Surveillance In Clinical Practice for Venous Thromboembolism (VTE) Treatment and Prevention Of Recurrent VTE","status":"COMPLETED","sponsor":"Bristol-Myers Squibb","startDate":"2016-07-01","conditions":"Venous Thromboembolism","enrollment":1134},{"nctId":"NCT05221879","phase":"NA","title":"Anti-factor Xa Based Venous Thromboembolism Prophylaxis","status":"COMPLETED","sponsor":"Meir Medical Center","startDate":"2019-06-23","conditions":"Dose Adjustment of Enoxaparin in ICU Patients","enrollment":75},{"nctId":"NCT02046096","phase":"NA","title":"Cook IVC Filter Study","status":"COMPLETED","sponsor":"Cook Research Incorporated","startDate":"2014-01","conditions":"Pulmonary Embolism","enrollment":473},{"nctId":"NCT04416048","phase":"PHASE2","title":"Effect of Anticoagulation Therapy on Clinical Outcomes in COVID-19","status":"TERMINATED","sponsor":"Charite University, Berlin, Germany","startDate":"2020-11-30","conditions":"COVID-19","enrollment":111}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1523,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Rivaroxaban","Xarelto","anticoag","Direct oral anticoagulant","DOAC"],"phase":"phase_3","status":"active","brandName":"Prevention of Venous Thromboembolism","genericName":"Prevention of Venous Thromboembolism","companyName":"Prof. Stavros Konstantinides, MD","companyId":"prof-stavros-konstantinides-md","modality":"Small molecule","firstApprovalDate":"","aiSummary":"This drug prevents the formation of blood clots in the veins by inhibiting the coagulation cascade. Used for Prevention of venous thromboembolism in patients undergoing major orthopedic surgery.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}