{"id":"prevenar-and-meningitec","safety":{"commonSideEffects":[{"rate":"20–50","effect":"Injection site erythema, swelling, or pain"},{"rate":"10–30","effect":"Fever"},{"rate":"10–20","effect":"Irritability or fussiness"},{"rate":"5–15","effect":"Myalgia or fatigue"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Prevenar is a pneumococcal conjugate vaccine targeting 13 serotypes of Streptococcus pneumoniae, while Meningitec is a meningococcal conjugate vaccine targeting serogroup C. Both work by conjugating bacterial polysaccharide capsules to diphtheria toxoid or other protein carriers, enabling T-cell dependent immune responses that generate long-lasting antibody protection against invasive bacterial disease.","oneSentence":"These are conjugate vaccines that stimulate the immune system to produce antibodies against specific bacterial pathogens by linking polysaccharide antigens to protein carriers.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:36:34.691Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of invasive pneumococcal disease caused by 13 serotypes of Streptococcus pneumoniae (Prevenar)"},{"name":"Prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroup C (Meningitec)"}]},"trialDetails":[{"nctId":"NCT00463437","phase":"PHASE3","title":"Pneumococcal Vaccine Booster Study in Healthy Children 11-18 Months Old Previously Primed With the Same Vaccines","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2007-04-25","conditions":"Hepatitis B, Acellular Pertussis, Tetanus","enrollment":1437},{"nctId":"NCT00127855","phase":"PHASE2","title":"Dose Ranging Study of Combined Haemophilus Influenzae Type B-Meningococcal Serogroups CY (Hib-MenCY-TT) Vaccine","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2003-03-01","conditions":"Haemophilus Influenzae Type b, Neisseria Meningitidis","enrollment":409},{"nctId":"NCT00134719","phase":"PHASE2","title":"Hib-MenCY-TT Vaccine Study Compared to Licensed Hib and Meningococcal Serogroup C Conjugate Vaccines","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2005-04-11","conditions":"Neisseria Meningitidis, Haemophilus Influenzae Type b","enrollment":1104},{"nctId":"NCT00891176","phase":"PHASE3","title":"Persistence of Antibodies at 3, 4 and 6 Years of Age After Vaccination With Meningococcal, Pneumococcal and Hib Vaccines","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2009-05-14","conditions":"Neisseria Meningitidis, Haemophilus Influenzae Type b","enrollment":582},{"nctId":"NCT00581035","phase":"PHASE4","title":"Study Evaluating the Safety and Ability to Produce Immune Response of Prevenar and Meningitec Given at the Same Time","status":"COMPLETED","sponsor":"Wyeth is now a wholly owned subsidiary of Pfizer","startDate":"2006-01","conditions":"Healthy","enrollment":712}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":4,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Prevenar and Meningitec","genericName":"Prevenar and Meningitec","companyName":"Wyeth is now a wholly owned subsidiary of Pfizer","companyId":"wyeth-is-now-a-wholly-owned-subsidiary-of-pfizer","modality":"Biologic","firstApprovalDate":"","aiSummary":"These are conjugate vaccines that stimulate the immune system to produce antibodies against specific bacterial pathogens by linking polysaccharide antigens to protein carriers. Used for Prevention of invasive pneumococcal disease caused by 13 serotypes of Streptococcus pneumoniae (Prevenar), Prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroup C (Meningitec).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}