{"id":"preoperative-normal-saline-inhalation","safety":{"commonSideEffects":[{"rate":null,"effect":"Mild throat irritation"},{"rate":null,"effect":"Cough"},{"rate":null,"effect":"Transient bronchospasm (rare)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Inhaled normal saline (0.9% sodium chloride solution) acts as a mucosal hydrating agent that moistens the airways and helps mobilize and clear secretions from the respiratory tract. This preoperative preparation reduces airway irritation, improves mucociliary clearance, and may decrease postoperative respiratory complications by ensuring optimal airway patency at the time of anesthesia induction.","oneSentence":"Normal saline inhalation administered preoperatively hydrates and clears the respiratory tract to optimize airway conditions before surgery.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:02:35.297Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Preoperative airway preparation and hydration"},{"name":"Reduction of postoperative respiratory complications"}]},"trialDetails":[{"nctId":"NCT03868709","phase":"PHASE4","title":"Prophylactic Penehyclidine Hydrochloride Inhalation and 3-year Outcome After Surgery","status":"COMPLETED","sponsor":"Peking University First Hospital","startDate":"2019-03-12","conditions":"Postoperative Complications, Long-term Outcome","enrollment":864},{"nctId":"NCT06302985","phase":"NA","title":"Atomized Inhalation ICG for Treatment of Congenital Lung Malformations","status":"RECRUITING","sponsor":"Jiexiong Feng","startDate":"2024-03-01","conditions":"Pulmonary Sequestration, Congenital Pulmonary Airway Malformation, Indocyanine Green","enrollment":50},{"nctId":"NCT06158893","phase":"PHASE4","title":"Comparison of Preoperative Inhaled Budesonide With Salbutamol on the Respiratory Adverse Effects in Children Undergoing Tonsillectomy","status":"UNKNOWN","sponsor":"Assiut University","startDate":"2024-08","conditions":"Preoperative Inhalation of Budesonide and Salbutamol in Children Undergoing Tonsillectomy","enrollment":87},{"nctId":"NCT04997655","phase":"","title":"The Effect of Upper Transabdominal Plain Block on Diaphragm Thickness","status":"COMPLETED","sponsor":"Konya City Hospital","startDate":"2022-06-02","conditions":"Anesthesia, General","enrollment":67},{"nctId":"NCT04544228","phase":"NA","title":"Ketamine or Neostigmine for Serratus Anterior Plane Block in Modified Radical Mastectomy","status":"COMPLETED","sponsor":"Cairo University","startDate":"2020-09-05","conditions":"Postoperative Pain","enrollment":90},{"nctId":"NCT02644876","phase":"PHASE4","title":"Preventive Effects of Penehyclidine Hydrochloride Inhalation on Postoperative Pulmonary Complications","status":"COMPLETED","sponsor":"Peking University First Hospital","startDate":"2015-09-01","conditions":"Postoperative Complications","enrollment":864},{"nctId":"NCT03394222","phase":"PHASE4","title":"Effect of Preoperative Budesonide Inhalation on Arterial Blood Oxygenation and Intrapulmonary Shunt During OLV","status":"COMPLETED","sponsor":"Fujian Medical University Union Hospital","startDate":"2016-07","conditions":"Lung Cancer","enrollment":50},{"nctId":"NCT02097407","phase":"PHASE4","title":"Preoperative Dexmedetomidine & EC50 of Propofol","status":"COMPLETED","sponsor":"Seoul National University Hospital","startDate":"2012-05","conditions":"Urologic Surgery","enrollment":37}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"preoperative normal saline inhalation","genericName":"preoperative normal saline inhalation","companyName":"Fujian Medical University Union Hospital","companyId":"fujian-medical-university-union-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Normal saline inhalation administered preoperatively hydrates and clears the respiratory tract to optimize airway conditions before surgery. Used for Preoperative airway preparation and hydration, Reduction of postoperative respiratory complications.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}