{"id":"prednisolones-acetate","safety":{"commonSideEffects":[{"rate":"null","effect":"Increased intraocular pressure"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"It does this by binding to glucocorticoid receptors in the cytoplasm, which then translocate to the nucleus and regulate the expression of genes involved in inflammation. This results in a decrease in the production of pro-inflammatory cytokines and an increase in the production of anti-inflammatory cytokines.","oneSentence":"Prednisolone acetate is a corticosteroid that suppresses inflammation and immune responses by inhibiting the production of inflammatory cytokines and mediators.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:30:02.185Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Treatment of uveitis"}]},"trialDetails":[{"nctId":"NCT01475643","phase":"PHASE3","title":"Loteprednol vs Prednisolone for the Treatment of Intraocular Inflammation Following Cataract Surgery in Children.","status":"COMPLETED","sponsor":"Bausch & Lomb Incorporated","startDate":"2013-06","conditions":"Cataract","enrollment":107}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["PA"],"phase":"phase_3","status":"active","brandName":"Prednisolones acetate","genericName":"Prednisolones acetate","companyName":"Bausch & Lomb Incorporated","companyId":"bausch-lomb-incorporated","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Prednisolone acetate is a corticosteroid that suppresses inflammation and immune responses by inhibiting the production of inflammatory cytokines and mediators. Used for Treatment of uveitis.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}