{"id":"prednisolone-steaglate","rwe":[],"tags":[{"label":"Corticosteroid","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Anti-Inflammatory Agents","category":"pharmacology"},{"label":"Antineoplastic Agents","category":"pharmacology"},{"label":"Antineoplastic Agents, Hormonal","category":"pharmacology"},{"label":"Glucocorticoids","category":"pharmacology"},{"label":"Hormones","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"sintisone","offLabel":[],"synonyms":["prednisolone steaglate","prednisolone stearoylglycolate","sintisone"],"timeline":[],"approvals":[],"brandName":"Sintisone","ecosystem":[],"mechanism":{"moaClass":"Corticosteroid Hormone Receptor Agonists","modality":"Small Molecule","drugClass":"Corticosteroid","explanation":"Imagine your immune system is like a fire that gets out of control when it's fighting an infection. Sintisone helps put out the fire by reducing the production of chemicals that cause inflammation, which in turn reduces swelling and pain.","oneSentence":"Sintisone works by suppressing the immune system's inflammatory response to reduce swelling and pain.","technicalDetail":"Sintisone, a prednisolone ester, is a corticosteroid that exerts its anti-inflammatory effects by inhibiting the transcription of inflammatory genes, thereby reducing the production of pro-inflammatory cytokines and mediators."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2249","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=PREDNISOLONE STEAGLATE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:28:11.300142","biosimilars":[],"competitors":[],"genericName":"prednisolone steaglate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"MMSL":"5347","NDDF":"002155","UNII":"OZQ2XN817F","CHEBI":"CHEBI:135871","VANDF":"4017988","INN_ID":"2071","RXNORM":"8638","UMLSCUI":"C2825346","ChEMBL_ID":"CHEMBL2105774","KEGG_DRUG":"D08415","DRUGBANK_ID":"DB00860","PDB_CHEM_ID":" TUA","PUBCHEM_CID":"71206","SNOMEDCT_US":"116601002","MESH_DESCRIPTOR_UI":"D011239","MESH_SUPPLEMENTAL_RECORD_UI":"C003312"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Immunology"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Sintisone is a small molecule medication. It is also known by other names, including Prednisolone 21-stearoylglycolate, Prednisolone Steaglate, and Prednisolone 21-stearoylglycolate.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}