{"id":"prednisolone-acetate-1-ophthalmic-suspension","safety":{"commonSideEffects":[{"rate":null,"effect":"Elevated intraocular pressure"},{"rate":null,"effect":"Posterior subcapsular cataract formation"},{"rate":null,"effect":"Secondary ocular infection"},{"rate":null,"effect":"Ocular irritation or discomfort"},{"rate":null,"effect":"Blurred vision"}]},"_chembl":{"chemblId":"CHEMBL1697848","moleculeType":"Small molecule","molecularWeight":"486.61"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Prednisolone acetate binds to glucocorticoid receptors in ocular tissues, leading to decreased synthesis of prostaglandins, leukotrienes, and other inflammatory mediators. This reduces infiltration of inflammatory cells, decreases vascular permeability, and suppresses both humoral and cell-mediated immune responses in the eye. 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Used for Inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe, Steroid-responsive inflammatory conditions of the eye such as allergic conjunctivitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}