{"id":"prednisolamate","rwe":[],"tags":[{"label":"Corticosteroid","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Anti-Inflammatory Agents","category":"pharmacology"},{"label":"Antineoplastic Agents","category":"pharmacology"},{"label":"Antineoplastic Agents, Hormonal","category":"pharmacology"},{"label":"Glucocorticoids","category":"pharmacology"},{"label":"Hormones","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"etaproctene","offLabel":[],"synonyms":["prednisolone 21-diethylaminoacetate","prednisolamate","prednisolamate hydrochloride","etaproctene"],"timeline":[],"approvals":[],"brandName":"Etaproctene","ecosystem":[],"mechanism":{"moaClass":"Corticosteroid Hormone Receptor Agonists","modality":"Small Molecule","drugClass":"Corticosteroid","explanation":"Imagine your immune system is like a fire alarm that goes off when it senses danger. Corticosteroids like Etaproctene are like a fire alarm silencer that reduces the alarm's sensitivity, helping to calm down the immune response and reduce inflammation. This can be helpful for treating conditions like arthritis or asthma, but it can also increase the risk of infections and other side effects.","oneSentence":"Etaproctene works by binding to glucocorticoid receptors in the body, which then suppresses the immune system and reduces inflammation.","technicalDetail":"Etaproctene exerts its effects by binding to glucocorticoid receptors (GR) in the cytoplasm, which then translocate to the nucleus and regulate the expression of target genes involved in inflammation and immune response, including the induction of anti-inflammatory proteins and the suppression of pro-inflammatory cytokines."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3820","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=PREDNISOLAMATE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:28:08.250020","biosimilars":[],"competitors":[],"genericName":"prednisolamate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"MMSL":"5347","NDDF":"002155","UNII":"W262JY01SG","CHEBI":"CHEBI:135763","VANDF":"4017988","INN_ID":"1531","RXNORM":"8638","UMLSCUI":"C5418516","ChEMBL_ID":"CHEMBL2106961","DRUGBANK_ID":"DB00860","PDB_CHEM_ID":" TUA","PUBCHEM_CID":"20055007","SNOMEDCT_US":"116601002","SECONDARY_CAS_RN":"17140-01-1","MESH_DESCRIPTOR_UI":"D011239"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Immunology"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Etaproctene, also known as Prednisolamate, is a corticosteroid small molecule drug. It is used to treat various conditions, although its specific indications are not provided. As a corticosteroid, it works by suppressing the immune system and reducing inflammation. The commercial status of Etaproctene is unknown, and it may be patented or generic. Key safety considerations include the potential for side effects associated with corticosteroid use.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}