{"id":"pr-sandoz-tamsulosin","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Dizziness"},{"rate":"5-10%","effect":"Headache"},{"rate":"5-10%","effect":"Nausea"},{"rate":"5-10%","effect":"Diarrhea"},{"rate":"5-10%","effect":"Fatigue"}]},"_chembl":{"chemblId":"CHEMBL1200914","moleculeType":"Small molecule","molecularWeight":"444.98"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"By blocking alpha-1 adrenergic receptors, tamsulosin reduces the muscle tone in the prostate and bladder neck, making it easier to urinate. This is particularly beneficial for men with benign prostatic hyperplasia (BPH).","oneSentence":"Tamsulosin is an alpha-1 adrenergic receptor antagonist that relaxes smooth muscles in the prostate and bladder neck, improving urine flow.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:29:46.329Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Benign prostatic hyperplasia (BPH) symptoms"},{"name":"Lower urinary tract symptoms (LUTS)"}]},"trialDetails":[{"nctId":"NCT05941806","phase":"PHASE3","title":"Prophylactic Use of Tamsulosin in the Prevention of Post-operative Urinary Retention in Men After Rectum Resection","status":"UNKNOWN","sponsor":"CHU de Quebec-Universite Laval","startDate":"2023-08-01","conditions":"Urinary Retention, Colorectal Surgery, Rectal Resection","enrollment":220}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Tamsulosin hydrochloride"],"phase":"phase_3","status":"active","brandName":"pr Sandoz Tamsulosin","genericName":"pr Sandoz Tamsulosin","companyName":"CHU de Quebec-Universite Laval","companyId":"chu-de-quebec-universite-laval","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Pr Sandoz Tamsulosin is a small molecule that acts as an adrenergic receptor alpha-1 antagonist. It is used to prevent post-operative urinary retention in men after rectum resection.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}