{"id":"posatirelin","rwe":[],"tags":[{"label":"posatirelin","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"pyladox","offLabel":[],"synonyms":["posatireline","RGH-2202","pyladox","posatirelin"],"timeline":[],"approvals":[],"brandName":"Pyladox","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"posatirelin","explanation":"Imagine your body has a 'growth hormone factory' in the pituitary gland. Pyladox helps to stimulate this factory, releasing more growth hormone into the bloodstream. This can help to promote growth and development in certain conditions.","oneSentence":"Pyladox (posatirelin) is thought to work by stimulating the release of growth hormone from the pituitary gland.","technicalDetail":"Posatirelin is a synthetic peptide analog that acts as a potent stimulator of growth hormone release, likely through interaction with growth hormone-releasing hormone receptors in the pituitary gland."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3484","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=POSATIRELIN","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:22:42.929739","biosimilars":[],"competitors":[],"genericName":"posatirelin","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"78U6302ARL","CHEBI":"CHEBI:135486","INN_ID":"6310","UMLSCUI":"C0285748","ChEMBL_ID":"CHEMBL2105243","PUBCHEM_CID":"71230","MESH_SUPPLEMENTAL_RECORD_UI":"C055448"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":10,"therapeuticAreas":["Hematology"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Recombinant protein","firstApprovalDate":"","aiSummary":"Pyladox is a protein modality. It is also known by the synonyms POSATIRELIN, POSATIRELINA, and POSATIRELINE.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}