{"id":"polyethylene-glycol-ointment-placebo","safety":{"commonSideEffects":[{"rate":null,"effect":"Skin irritation or sensitization to ointment base"},{"rate":null,"effect":"Local erythema or contact dermatitis"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"As a placebo formulation, polyethylene glycol ointment contains no active pharmaceutical ingredient and exerts no therapeutic mechanism of action. It is used in clinical trials as a control comparator to assess the efficacy of active treatments by accounting for placebo effects. The ointment base itself may provide minimal skin hydration through occlusion, but this is not considered a therapeutic mechanism.","oneSentence":"Polyethylene glycol ointment is an inert, occlusive topical vehicle that provides no active pharmacological effect and serves as a placebo control.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:36:20.680Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Placebo control in clinical trials"}]},"trialDetails":[],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["PEG Ointment"],"phase":"marketed","status":"active","brandName":"Polyethylene Glycol Ointment [Placebo]","genericName":"Polyethylene Glycol Ointment [Placebo]","companyName":"US Department of Veterans Affairs","companyId":"us-department-of-veterans-affairs","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Polyethylene glycol ointment is an inert, occlusive topical vehicle that provides no active pharmacological effect and serves as a placebo control. Used for Placebo control in clinical trials.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":false,"score":3}}