{"id":"pneumoccocal-vaccine","safety":{"commonSideEffects":[{"rate":"20-50","effect":"Injection site pain, erythema, or swelling"},{"rate":"5-15","effect":"Fever"},{"rate":"5-20","effect":"Myalgia or fatigue"},{"rate":"5-15","effect":"Headache"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The vaccine contains antigens derived from pneumococcal polysaccharide capsules or conjugated to carrier proteins. These antigens trigger both humoral and cellular immune responses, enabling the body to recognize and neutralize pneumococcal pathogens before they cause invasive disease. Multiple serotypes are included to provide broad protection against common disease-causing strains.","oneSentence":"Pneumococcal vaccine stimulates the immune system to produce antibodies against Streptococcus pneumoniae bacteria, preventing infection and disease.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:29:21.193Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of pneumococcal disease (bacteremia, meningitis, pneumonia) in adults and children"}]},"trialDetails":[{"nctId":"NCT05794230","phase":"PHASE3","title":"Study of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Given With Routine Pediatric Vaccines in Healthy Infants and Toddlers in India and the Republic of South Africa","status":"COMPLETED","sponsor":"Sanofi Pasteur, a Sanofi Company","startDate":"2023-03-27","conditions":"Meningococcal Immunisation, Healthy Volunteers","enrollment":1528},{"nctId":"NCT00918580","phase":"PHASE3","title":"Study Evaluating 13-valent Pneumococcal Conjugate Vaccine (13vPnC) in Children With Sickle Cell Disease","status":"COMPLETED","sponsor":"Pfizer","startDate":"2009-11","conditions":"Pneumococcal Conjugate Vaccine","enrollment":158},{"nctId":"NCT00843895","phase":"NA","title":"Multicenter Prospective Evaluation of the Incidence and Serotyes of Invasive Pneumoccocal Disease (IPD) Among Children Below 5 Years","status":"UNKNOWN","sponsor":"King Saud University","startDate":"2009-03","conditions":"Pneumococcal Disease","enrollment":400}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Prevnar 13®"],"phase":"phase_3","status":"active","brandName":"Pneumoccocal Vaccine","genericName":"Pneumoccocal Vaccine","companyName":"Sanofi Pasteur, a Sanofi Company","companyId":"sanofi","modality":"Biologic","firstApprovalDate":"","aiSummary":"Pneumococcal vaccine stimulates the immune system to produce antibodies against Streptococcus pneumoniae bacteria, preventing infection and disease. Used for Prevention of pneumococcal disease (bacteremia, meningitis, pneumonia) in adults and children.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}