{"id":"plasma-lyte-static-group","safety":{"commonSideEffects":[{"rate":null,"effect":"Hyperkalemia"},{"rate":null,"effect":"Hypokalemia"},{"rate":null,"effect":"Hypernatremia"},{"rate":null,"effect":"Hyponatremia"},{"rate":null,"effect":"Fluid overload / Pulmonary edema"},{"rate":null,"effect":"Phlebitis at infusion site"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Plasma-Lyte is a crystalloid intravenous fluid containing a physiologically balanced mixture of electrolytes (sodium, potassium, magnesium, calcium, chloride, acetate, and gluconate) designed to closely mimic plasma composition. It is used for fluid resuscitation and maintenance therapy to restore intravascular volume and correct electrolyte imbalances without causing hyperchloremic acidosis or other electrolyte disturbances associated with normal saline.","oneSentence":"Plasma-Lyte is a balanced electrolyte solution that replaces fluid and electrolytes lost through dehydration, hemorrhage, or other medical conditions.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:01:36.804Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Fluid resuscitation and maintenance in dehydration"},{"name":"Perioperative fluid management"},{"name":"Hemorrhage and acute blood loss replacement"},{"name":"Electrolyte imbalance correction"}]},"trialDetails":[{"nctId":"NCT06080178","phase":"PHASE4","title":"Goal-directed Fluid Therapy During Deep Inferior Epigastric Perforator (DIEP) Free Flap Breast Reconstruction","status":"RECRUITING","sponsor":"Algemeen Ziekenhuis Maria Middelares","startDate":"2023-11-23","conditions":"Hypotension During Surgery","enrollment":82}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Plasma-lyte (static group)","genericName":"Plasma-lyte (static group)","companyName":"Algemeen Ziekenhuis Maria Middelares","companyId":"algemeen-ziekenhuis-maria-middelares","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Plasma-Lyte is a balanced electrolyte solution that replaces fluid and electrolytes lost through dehydration, hemorrhage, or other medical conditions. Used for Fluid resuscitation and maintenance in dehydration, Perioperative fluid management, Hemorrhage and acute blood loss replacement.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}