{"id":"plain-aqueous-gel","safety":{"commonSideEffects":[{"rate":null,"effect":"Local irritation or sensitization"},{"rate":null,"effect":"Allergic contact dermatitis"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This is a non-medicated aqueous gel formulation used primarily as a lubricant, moisturizer, or inert delivery vehicle. It functions through physical hydration and protective barrier effects on skin or mucous membranes rather than through specific molecular target engagement.","oneSentence":"Plain aqueous gel provides a water-based vehicle for topical delivery and lubrication without active pharmaceutical ingredients.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:01:32.031Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Skin lubrication and hydration"},{"name":"Wound care and dressing"}]},"trialDetails":[{"nctId":"NCT03637582","phase":"NA","title":"Contribution of Urethral Sensory Feedback in Voiding Efficiency","status":"COMPLETED","sponsor":"Duke University","startDate":"2018-11-26","conditions":"Urethral Anesthesia","enrollment":18},{"nctId":"NCT02823431","phase":"NA","title":"Effect of Urethral Analgesia on Voiding","status":"COMPLETED","sponsor":"Duke University","startDate":"2016-07","conditions":"Urethral Analgesia","enrollment":23},{"nctId":"NCT00883103","phase":"PHASE4","title":"Double Blinded Randomized Trial Between Lidocaine And Plain Gel For Urethral Straight Catheterization And The Q-Tip Test","status":"COMPLETED","sponsor":"Baystate Medical Center","startDate":"2007-11","conditions":"Pain","enrollment":137}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Surgilube"],"phase":"marketed","status":"active","brandName":"Plain aqueous gel","genericName":"Plain aqueous gel","companyName":"Baystate Medical Center","companyId":"baystate-medical-center","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Plain aqueous gel is a substance studied in clinical trials for conditions such as urethral anesthesia, urethral analgesia, and pain. The exact mechanism of action of plain aqueous gel is unknown.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}