{"id":"placebo-slit-tablet","safety":{"commonSideEffects":[]},"_chembl":{"chemblId":"CHEMBL635","moleculeType":"Small molecule","molecularWeight":"358.43"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This is a placebo control formulation used in clinical trials for sublingual immunotherapy (SLIT). It contains no active allergen or immunological agent and serves as the comparator arm in phase 3 studies to establish the true efficacy of active SLIT-tablet formulations. Placebo tablets are essential for blinded trial design to distinguish genuine therapeutic effects from placebo response.","oneSentence":"A placebo sublingual immunotherapy tablet designed to assess efficacy and safety in phase 3 trials by delivering no active therapeutic agent.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:28:23.309Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Placebo control in phase 3 clinical trials for sublingual immunotherapy"}]},"trialDetails":[{"nctId":"NCT05440643","phase":"PHASE1, PHASE2","title":"Peanut Sublingual Immunotherapy (SLIT)-Tablet for Treatment of Peanut Allergy","status":"ACTIVE_NOT_RECRUITING","sponsor":"ALK-Abelló A/S","startDate":"2022-09-07","conditions":"Peanut Allergy","enrollment":192},{"nctId":"NCT07060885","phase":"PHASE3","title":"A Research Study of House Dust Mite (HDM) SLIT-tablet for the Treatment of HDM Allergy in Chinese Participants Aged 12-65","status":"RECRUITING","sponsor":"ALK-Abelló A/S","startDate":"2025-09-01","conditions":"Allergic Rhinoconjunctivitis, Allergic Rhinitis","enrollment":300},{"nctId":"NCT04502966","phase":"PHASE2","title":"Grass Pollen Immunotherapy Plus Dupilumab for Tolerance Induction","status":"COMPLETED","sponsor":"National Institute of Allergy and Infectious Diseases (NIAID)","startDate":"2020-11-09","conditions":"Allergic Rhinoconjunctivitis, Grass Pollen Allergy","enrollment":108},{"nctId":"NCT01199133","phase":"PHASE3","title":"Safety and Efficacy Study of Sublingual Immunotherapy (SLIT) to Treat House Dust Mite Allergic Rhinitis in Adolescents and Children","status":"TERMINATED","sponsor":"Stallergenes Greer","startDate":"2009-10","conditions":"Allergic Rhinitis Due to Dust Mite","enrollment":471},{"nctId":"NCT04878354","phase":"PHASE3","title":"A Study in Children and Adolescents With Birch Pollen-induced Rhinoconjunctivitis","status":"COMPLETED","sponsor":"ALK-Abelló 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Mite","enrollment":1460},{"nctId":"NCT03654976","phase":"PHASE3","title":"Mite Asthma Pediatric Immunotherapy Trial","status":"COMPLETED","sponsor":"ALK-Abelló A/S","startDate":"2018-02-22","conditions":"Allergic Asthma Due to Dermatophagoides Farinae, Allergic Asthma Due to Dermatophagoides Pteronyssinus, Allergic Rhinitis Due to House Dust Mite","enrollment":533},{"nctId":"NCT04176185","phase":"PHASE3","title":"A Research Study in Chinese People With Allergy to House Dust Mites, Using an Environmental Exposure Chamber","status":"TERMINATED","sponsor":"ALK-Abelló A/S","startDate":"2019-11-04","conditions":"Allergic Rhinoconjunctivitis","enrollment":80},{"nctId":"NCT02394600","phase":"PHASE4","title":"The Impact of Grass SLIT Treatment on Birch Pollen Induced Allergic Rhinitis - a Pilot Evaluation","status":"COMPLETED","sponsor":"Queen's University","startDate":"2015-04","conditions":"Allergic 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and Safety of 300 IR Sublingual Immunotherapy Tablets","status":"COMPLETED","sponsor":"Stallergenes Greer","startDate":"2006-12","conditions":"Allergy","enrollment":633},{"nctId":"NCT00803244","phase":"PHASE3","title":"Safety and Efficacy on Phase III Study on 300 IR SLIT to Patients Suffering From Grass Pollen Rhinoconjunctivitis","status":"COMPLETED","sponsor":"Stallergenes Greer","startDate":"2009-01","conditions":"Primary Disease","enrollment":381},{"nctId":"NCT00619827","phase":"PHASE1","title":"Efficacy and Safety of Sublingual Tablets of Grass Pollen Allergen Extract","status":"COMPLETED","sponsor":"Stallergenes Greer","startDate":"2007-09","conditions":"Seasonal Allergic Rhinitis","enrollment":89},{"nctId":"NCT00367640","phase":"PHASE2, PHASE3","title":"Safety and Efficacy of Sublingual Immunotherapy (SLIT) Tablets in Grass Pollen Rhinoconjunctivitis","status":"COMPLETED","sponsor":"Stallergenes Greer","startDate":"2004-11","conditions":"Allergy","enrollment":628},{"nctId":"NCT00955825","phase":"PHASE3","title":"Study of Efficacy and Safety of 300 IR Sublingual Immunotherapy (SLIT) Tablets in Adult Patients With Allergic Grass Pollen Rhinoconjunctivitis","status":"COMPLETED","sponsor":"Stallergenes Greer","startDate":"2008-10","conditions":"Allergic Rhinitis Due to Grass Pollens","enrollment":473},{"nctId":"NCT00674700","phase":"PHASE2, PHASE3","title":"Safety and Efficacy Study of Sublingual Immunotherapy (SLIT) to Treat House Dust Mite Allergic Rhinitis","status":"COMPLETED","sponsor":"Stallergenes Greer","startDate":"2007-10","conditions":"Allergic Rhinitis","enrollment":509},{"nctId":"NCT02245360","phase":"PHASE3","title":"Study Immunology and Safety of 60-day Treatment of SQ Grass SLIT (Sublingual Immunotherapy)-Tablet in Adult Subjects With Grass Pollen-induced Allergic Rhinoconjunctivitis","status":"COMPLETED","sponsor":"Abbott","startDate":"2014-10","conditions":"Seasonal Allergic Rhinitis","enrollment":107},{"nctId":"NCT01930461","phase":"PHASE2","title":"Dose Ranging Study of SLIT Tablets of House Dust Mite Allergen Extracts (HDM) in Adults With HDM-associated Allergic Asthma","status":"COMPLETED","sponsor":"Stallergenes Greer","startDate":"2013-09","conditions":"Asthma, House Dust Mite Allergy","enrollment":386},{"nctId":"NCT01608243","phase":"PHASE1","title":"Safety Study of Sublingual Immunotherapy Tablets of House Dust Mite Allergen Extracts","status":"COMPLETED","sponsor":"Stallergenes Greer","startDate":"2012-05","conditions":"Asthma, House Dust Mite Allergy","enrollment":94},{"nctId":"NCT00396149","phase":"PHASE1","title":"Safety, Tolerability and Pharmacodynamic Effects of Sublingual Immunotherapy (Tablets) With Recombinant Bet v1","status":"COMPLETED","sponsor":"Stallergenes Greer","startDate":"2006-11","conditions":"Birch Pollen-Related 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Seasonal","enrollment":55}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":72,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Placebo SLIT-tablet","genericName":"Placebo SLIT-tablet","companyName":"ALK-Abelló A/S","companyId":"alk-abell-a-s","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Placebo SLIT-tablet is a placebo treatment used in clinical trials for conditions such as allergy, peanut allergy, allergic rhinitis due to grass pollen, and allergic rhinoconjunctivitis. 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