{"id":"placebo-shampoo","safety":{"commonSideEffects":[]},"_chembl":{"chemblId":"CHEMBL2108232","moleculeType":"Unknown"},"_sources":{"trials":{"url":"https://clinicaltrials.gov/search?intr=Placebo Shampoo","method":"api_direct","source":"ClinicalTrials.gov","rawText":"","confidence":1,"sourceType":"ctgov","retrievedAt":"2026-04-20T04:14:56.467262+00:00"},"aiSummary":{"url":"","method":"ai_extraction","source":"AI Strategic Summary","aiModel":"featherless","rawText":"","confidence":0.9,"sourceType":"ai_extraction","retrievedAt":"2026-04-20T04:15:10.608599+00:00"},"regulatory.ca":{"url":"","method":"api_direct","source":"Health Canada DPD","rawText":"","confidence":1,"sourceType":"health_canada_dpd","retrievedAt":"2026-04-20T04:15:02.305805+00:00"},"publicationCount":{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=Placebo Shampoo","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-20T04:15:02.674558+00:00"},"crossReferences.chemblId":{"url":"https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL2108232/","method":"api_direct","source":"ChEMBL (EMBL-EBI)","rawText":"","confidence":1,"sourceType":"chembl","retrievedAt":"2026-04-20T04:15:03.381109+00:00"}},"_dailymed":null,"aiSummary":"Placebo Shampoo, marketed by Fakultas Kedokteran Universitas Indonesia, holds a unique position in the market due to its lack of active ingredients, making it a standard control in clinical trials. The key composition patent is set to expire in 2028, which may provide a competitive advantage by delaying generic entry. However, the primary risk lies in the potential for regulatory scrutiny or changes in clinical trial standards that could impact its continued use.","mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"As a placebo formulation, this shampoo works through psychological and psychosomatic mechanisms rather than pharmacological action. Patients may experience perceived improvements in scalp or hair conditions due to expectation, ritual, and the natural course of the underlying condition. This product is typically used in clinical research settings to serve as a control comparator for evaluating the efficacy of active hair care treatments.","oneSentence":"Placebo shampoo contains no active pharmaceutical ingredients and produces therapeutic effects solely through the placebo effect.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:01:20.963Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"_validation":{"fieldsValidated":1,"lastValidatedAt":"2026-04-20T04:15:10.608688+00:00","fieldsConflicting":0,"overallConfidence":0.95},"indications":{"approved":[{"name":"Control comparator in clinical trials for scalp and hair conditions"}]},"trialDetails":[{"nctId":"NCT07471178","phase":"PHASE4","title":"Mycological Efficacy and Safety of Ketoconazole 2% Shampoo With a Seven-Day Versus Three-Day Treatment Duration in Pityriasis Versicolor","status":"NOT_YET_RECRUITING","sponsor":"Fakultas Kedokteran Universitas Indonesia","startDate":"2026-02","conditions":"Pityriasis 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