{"id":"placebo-oral-soft-chew","safety":{"commonSideEffects":[{"rate":null,"effect":"Adverse events attributable to underlying condition rather than drug"}]},"_chembl":{"chemblId":"CHEMBL2108778","moleculeType":"Vaccine component"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Placebo formulations activate neural pathways associated with expectation and reward, leading to measurable changes in symptoms and biomarkers independent of pharmacological activity. The soft chew formulation is designed to be administered orally and may enhance the placebo effect through sensory cues and ritualistic administration. This is typically used in clinical research settings to serve as a control comparator for evaluating the true efficacy of active pharmaceutical agents.","oneSentence":"A placebo oral soft chew produces therapeutic effects primarily through the placebo effect, wherein patient expectation and psychological factors trigger physiological responses.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:42:10.916Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Clinical trial control comparator (non-therapeutic use)"}]},"trialDetails":[{"nctId":"NCT07054645","phase":"NA","title":"Elderberry Functional Gum and Cognitive & Oral Health in Older Adults","status":"NOT_YET_RECRUITING","sponsor":"Burdur Mehmet Akif Ersoy University","startDate":"2025-11-01","conditions":"Mild Cognitive Impairment (MCI), Aging, Oral Microbiome","enrollment":34},{"nctId":"NCT03989271","phase":"PHASE1, PHASE2","title":"Biological Effects of Quercetin in COPD","status":"UNKNOWN","sponsor":"Temple University","startDate":"2019-10-01","conditions":"Chronic Obstructive Pulmonary Disease","enrollment":29},{"nctId":"NCT04258410","phase":"PHASE4","title":"Quercetin for Cardio-Skeletal Muscle Health and Estrogen Deficiency","status":"WITHDRAWN","sponsor":"Wake Forest University Health Sciences","startDate":"2022-09","conditions":"Menopause Related Conditions","enrollment":""},{"nctId":"NCT02058368","phase":"PHASE3","title":"Study to Compare the Efficacy and Safety of Combination Treatment With Dutasteride and Tamsulosin With Tamsulosin Monotherapy, in Men With Moderate to Severe Benign Prostatic Hyperplasia","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2014-02-10","conditions":"Prostatic Hyperplasia","enrollment":607}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Placebo oral soft chew","genericName":"Placebo oral soft chew","companyName":"Wake Forest University Health Sciences","companyId":"wake-forest-university-health-sciences","modality":"Small molecule","firstApprovalDate":"","aiSummary":"A placebo oral soft chew produces therapeutic effects primarily through the placebo effect, wherein patient expectation and psychological factors trigger physiological responses. Used for Clinical trial control comparator (non-therapeutic use).","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}