{"id":"placebo-only-product-in-oral-dose-form","safety":{"commonSideEffects":[{"rate":null,"effect":"Placebo response (symptom improvement without active ingredient)"},{"rate":null,"effect":"Nocebo response (adverse events attributed to inert substance)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Placebo-only products are inert formulations used as control comparators in clinical trials to measure the effect of patient expectation, clinical attention, and natural disease progression independent of active drug effects. In Phase 3 trials, placebos establish the baseline therapeutic response attributable to non-pharmacological factors, allowing researchers to isolate the true efficacy of investigational treatments.","oneSentence":"A placebo product contains no active pharmaceutical ingredient and produces therapeutic effects solely through placebo response mechanisms.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:28:23.203Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Clinical trial control comparator (not a therapeutic product)"}]},"trialDetails":[{"nctId":"NCT06154447","phase":"PHASE1","title":"Evaluation of VX-828 in Healthy Participants and in Participants With Cystic Fibrosis","status":"RECRUITING","sponsor":"Vertex Pharmaceuticals Incorporated","startDate":"2023-12-12","conditions":"Cystic Fibrosis","enrollment":255},{"nctId":"NCT07339774","phase":"PHASE2","title":"Traditional Chinese Medicine Preparation Alleviates Radiotherapy-induced Oral Mucositis in Head and Neck Cancer Patients.","status":"RECRUITING","sponsor":"West China Hospital","startDate":"2026-03-30","conditions":"Radiotherapy-induced Oral Mucositis","enrollment":128},{"nctId":"NCT07485842","phase":"PHASE4","title":"FuKe Qianjin Capsule Plus Antibiotics for Chronic Endometritis","status":"NOT_YET_RECRUITING","sponsor":"Tianjin Medical University","startDate":"2026-04","conditions":"Chronic Endometritis","enrollment":300},{"nctId":"NCT07310264","phase":"PHASE1","title":"Research Into the Safety of a New Agent (VT-5006) in People With and Without Parkinson's Disease","status":"RECRUITING","sponsor":"Vertero Therapeutics","startDate":"2025-10-30","conditions":"Healthy Volunteers (HV), Parkinson's Disease (PD)","enrollment":84},{"nctId":"NCT07267559","phase":"PHASE4","title":"Dual Orexin Antagonism and Emotion and Affective Processing Study","status":"RECRUITING","sponsor":"University of Oxford","startDate":"2025-10-01","conditions":"Learning, Cognitive Functioning, Emotional Processing","enrollment":62},{"nctId":"NCT06562907","phase":"PHASE1","title":"Study of GS-4571 in Healthy Participants, Nondiabetic Obese Participants, and Nonobese Participants With Type 2 Diabetes Mellitus (T2DM)","status":"RECRUITING","sponsor":"Gilead Sciences","startDate":"2024-08-28","conditions":"Weight Management","enrollment":134},{"nctId":"NCT07473570","phase":"PHASE1","title":"A Study（Phase I）of GS3-007a Dry Suspension in Healthy Chinese Adults","status":"RECRUITING","sponsor":"Changchun GeneScience Pharmaceutical Co., Ltd.","startDate":"2026-01-07","conditions":"Healthy Adults","enrollment":32},{"nctId":"NCT07467746","phase":"PHASE2","title":"Research of Traditional Chinese Medicine Oral Preparation of C. Cicadae in the Treatment of ALS Patients With Elevated Plasma Sphingolipids","status":"NOT_YET_RECRUITING","sponsor":"The Third Xiangya Hospital of Central South University","startDate":"2026-04","conditions":"Amyotrophic Lateral Sclerosis","enrollment":84},{"nctId":"NCT04862221","phase":"PHASE2","title":"TReatment for ImmUne Mediated PathopHysiology","status":"RECRUITING","sponsor":"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)","startDate":"2022-02-09","conditions":"Acute Liver Failure, Fulminant Hepatic Failure, Hepatic Encephalopathy","enrollment":163},{"nctId":"NCT00939627","phase":"PHASE2","title":"Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent Cetuximab","status":"COMPLETED","sponsor":"National Cancer Institute (NCI)","startDate":"2009-07","conditions":"Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma, Recurrent Metastatic Squamous Neck Cancer With Occult Primary, Recurrent Salivary Gland Cancer","enrollment":55},{"nctId":"NCT07028853","phase":"PHASE3","title":"This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.","status":"RECRUITING","sponsor":"Pfizer","startDate":"2025-09-28","conditions":"Metastatic Castration Sensitive Prostate Cancer (mCSPC), Hormone Sensitive Prostate Cancer, Prostate Cancer","enrollment":1000},{"nctId":"NCT07431294","phase":"PHASE1","title":"A Study to Learn About How Safe Nitroglycerin is and How it Affects the Body When Taken Along With Nurandociguat in People With Coronary Artery Disease","status":"NOT_YET_RECRUITING","sponsor":"Bayer","startDate":"2026-04-07","conditions":"Stable Coronary Artery Disease","enrollment":36},{"nctId":"NCT07412288","phase":"PHASE1","title":"First-in-human Study of Orally Administered KT-579 in Healthy Adult Participants","status":"RECRUITING","sponsor":"Kymera Therapeutics, Inc.","startDate":"2026-02-23","conditions":"Healthy Participants","enrollment":96},{"nctId":"NCT06273540","phase":"PHASE1","title":"Phase1, STP7 Cocaine Drug-Drug Interaction Study","status":"COMPLETED","sponsor":"Stalicla SA","startDate":"2024-04-15","conditions":"Cocaine Use Disorder","enrollment":21},{"nctId":"NCT07429565","phase":"PHASE1","title":"Testing APPA-1 in Healthy Subjects and Osteoarthritis Patients","status":"COMPLETED","sponsor":"University of Liverpool","startDate":"2018-04-09","conditions":"Osteoarthritis","enrollment":40},{"nctId":"NCT05018585","phase":"PHASE3","title":"A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed With Type 1 Diabetes","status":"ACTIVE_NOT_RECRUITING","sponsor":"Diamyd Medical AB","startDate":"2022-05-19","conditions":"Type 1 Diabetes Mellitus","enrollment":330},{"nctId":"NCT06450210","phase":"PHASE1","title":"Safety for Home Administration of Microdose Psilocybin Use","status":"RECRUITING","sponsor":"Johns Hopkins University","startDate":"2024-12-06","conditions":"Psychedelic Experiences","enrollment":20},{"nctId":"NCT07412938","phase":"PHASE1","title":"JKN2306 in Healthy Subjects: Single Ascending Dose and Food Effect Study","status":"COMPLETED","sponsor":"Joincare Pharmaceutical Group Industry Co., Ltd","startDate":"2025-02-12","conditions":"Acute Pain","enrollment":44},{"nctId":"NCT07169279","phase":"PHASE2","title":"Interventional Study of Infigratinib in Children < 3 Years Old With Achondroplasia (ACH)","status":"RECRUITING","sponsor":"QED Therapeutics, a BridgeBio company","startDate":"2025-11-19","conditions":"Achondroplasia","enrollment":77},{"nctId":"NCT07393256","phase":"NA","title":"Effect of Probiotics on Constipation and Weight in CP","status":"COMPLETED","sponsor":"Ordu University","startDate":"2022-11-01","conditions":"Cerebral Palsy (CP), Constipation, Probiotic","enrollment":30},{"nctId":"NCT06961019","phase":"NA","title":"Clinical Study to Assess the Safety, Efficacy and In-Use Tolerability of Herbal-Based Sugar Support Effervescent Tablets in Type-2 Diabetes Mellitus Patients","status":"RECRUITING","sponsor":"NovoBliss Research Pvt Ltd","startDate":"2025-08-25","conditions":"Type2 Diabetes Mellitus","enrollment":14},{"nctId":"NCT06310967","phase":"PHASE1, PHASE2","title":"A Dose Escalation Study of IG3018 in Subjects With Hyperuricemia With or Without Chronic Kidney Disease","status":"RECRUITING","sponsor":"Intelligem Therapeutics Australia Pty Ltd.","startDate":"2024-11-12","conditions":"Hyperuricemia, Hypouricemia, Renal","enrollment":60},{"nctId":"NCT06605768","phase":"NA","title":"Study Evaluating the Effects of Dietary Supplement on Hair Thickness and Hair Strength in Individuals With Self-Perceived Thinning Hair","status":"COMPLETED","sponsor":"Nutra Harmony LLC","startDate":"2024-02-19","conditions":"Hair Thinning","enrollment":80},{"nctId":"NCT05532293","phase":"PHASE1","title":"Phase One Clinical Trial to Assess the Safety, Tolerability and Pharmacokinetics of MSP008-22 in Healthy Adult Volunteers","status":"COMPLETED","sponsor":"Godavari Biorefineries Limited","startDate":"2022-12-02","conditions":"COVID-19","enrollment":64},{"nctId":"NCT03341078","phase":"PHASE2","title":"Pilot Study of the Effect of Ibudilast on Neuroinflammation in Methamphetamine Users","status":"COMPLETED","sponsor":"VA Office of Research and Development","startDate":"2019-05-01","conditions":"Methamphetamine-dependence","enrollment":176},{"nctId":"NCT07162623","phase":"NA","title":"Clinical Study to Assess Safety, Efficacy and In-Use Tolerability of Oziva Bioactive Gluta Fizzy Effervescent Tablets on Subjects With Facial Dark Spots Such as Pimple Marks, Sunspots, Age Spots and Uneven Skin Tone","status":"ACTIVE_NOT_RECRUITING","sponsor":"NovoBliss Research Pvt Ltd","startDate":"2025-09-02","conditions":"Hyperpigmentation","enrollment":60},{"nctId":"NCT07374354","phase":"NA","title":"Preemptive Analgesia for Pain and Anxiety Control in Children With MIH","status":"RECRUITING","sponsor":"October University for Modern Sciences and Arts","startDate":"2026-02","conditions":"Pain and Anxiety in Children With MIH","enrollment":46},{"nctId":"NCT07363057","phase":"PHASE2","title":"A Study to Evaluate the Effects of the Combination of GI-102 With GIB-7 on Biomarkers of Aging in Healthy Adults and Cancer Survivors","status":"RECRUITING","sponsor":"GI Innovation, Inc.","startDate":"2026-01","conditions":"Cancer Survivors, Healthy Participant, Elderly","enrollment":15},{"nctId":"NCT07364565","phase":"NA","title":"The Antiplaque and Antigingivitis Effect of Pure Green Tea Mouth Wash Compared to Placebo and Essential Oils Mouth Washes","status":"RECRUITING","sponsor":"King Abdullah University Hospital","startDate":"2025-12-01","conditions":"Dental Plaque, Patient Reported Outcome, Gingival Inflammation and Bleeding","enrollment":44},{"nctId":"NCT07357376","phase":"PHASE3","title":"Evaluating Suzetrigine for Pain Control Following TKA","status":"NOT_YET_RECRUITING","sponsor":"AdventHealth","startDate":"2026-03-01","conditions":"Postoperative Pain Following Knee Arthroplasty","enrollment":210},{"nctId":"NCT05230758","phase":"PHASE3","title":"Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour","status":"RECRUITING","sponsor":"Donald Mabbott","startDate":"2022-07-01","conditions":"Medulloblastoma, Childhood, Cognitive Impairment","enrollment":140},{"nctId":"NCT06404086","phase":"PHASE2","title":"RECOVER-SLEEP: Platform Protocol","status":"COMPLETED","sponsor":"Duke University","startDate":"2024-07-31","conditions":"Long COVID, Long COVID-19, Hypersomnia","enrollment":830},{"nctId":"NCT06101784","phase":"PHASE1, PHASE2","title":"Single and Multiple Ascending Oral Doses of Avenanthramide","status":"RECRUITING","sponsor":"Montreal Heart Institute","startDate":"2023-12-09","conditions":"Inflammation","enrollment":96},{"nctId":"NCT05776459","phase":"PHASE2","title":"Efficacy and Safety of AC102 Compared to Steroids in Adults With Idiopathic Sudden Sensorineural Hearing Loss (ISSNHL)","status":"ACTIVE_NOT_RECRUITING","sponsor":"AudioCure Pharma GmbH","startDate":"2022-10-13","conditions":"Hearing Loss, Sensorineural","enrollment":210},{"nctId":"NCT04530123","phase":"PHASE2","title":"Dose-Ranging Study of the Efficacy and Safety of TAK-101 for Prevention of Gluten-Specific T Cell Activation in Participants With Celiac Disease on a Gluten-Free Diet","status":"COMPLETED","sponsor":"Takeda","startDate":"2022-06-23","conditions":"Celiac Disease","enrollment":102},{"nctId":"NCT01988883","phase":"EARLY_PHASE1","title":"Modafinil and Cognitive Function in POTS","status":"ACTIVE_NOT_RECRUITING","sponsor":"Vanderbilt University Medical Center","startDate":"2014-10","conditions":"Postural Tachycardia Syndrome","enrollment":20},{"nctId":"NCT06698926","phase":"PHASE1","title":"A Study to Assess the Safety, Tolerability, and Interactions of ABBV-CLS-616 Oral Tablets in Healthy Adult Participants","status":"COMPLETED","sponsor":"AbbVie","startDate":"2024-11-11","conditions":"Healthy Volunteer","enrollment":110},{"nctId":"NCT04746183","phase":"PHASE1, PHASE2","title":"AGILE (Early Phase Platform Trial for COVID-19)","status":"RECRUITING","sponsor":"University of Liverpool","startDate":"2020-07-03","conditions":"Covid19","enrollment":600},{"nctId":"NCT06236061","phase":"PHASE3","title":"Study of Efficacy and Safety of LCZ696/Amlodipine in Grade 1 and 2 Hypertension Patients Uncontrolled by LCZ696 Monotherapy","status":"COMPLETED","sponsor":"Novartis Pharmaceuticals","startDate":"2024-04-08","conditions":"Hypertension","enrollment":718},{"nctId":"NCT06895486","phase":"PHASE2","title":"Study of Co-administered (Types 1 & 2) Novel Oral Poliomyelitis Vaccines Evaluation","status":"RECRUITING","sponsor":"PATH","startDate":"2025-11-11","conditions":"Poliomyelitis","enrollment":675},{"nctId":"NCT03849443","phase":"EARLY_PHASE1","title":"Single Versus Multi-Dose Oral and Intravenous Tranexamic Acid Patients at High Risk for Blood Transfusion After Spine Surgery","status":"RECRUITING","sponsor":"Rush University Medical Center","startDate":"2019-08-26","conditions":"Open Posterior Thoracolumbar Spinal Fusion Procedure","enrollment":604},{"nctId":"NCT07324018","phase":"PHASE2","title":"Spirulina Derivative for Radiation Esophagitis","status":"NOT_YET_RECRUITING","sponsor":"West China Hospital","startDate":"2026-01-12","conditions":"Radiation-induced Esophagitis","enrollment":70},{"nctId":"NCT07327281","phase":"PHASE1","title":"A Clinical Trial Evaluating TQF3250 Capsules in Healthy Adult Subjects","status":"RECRUITING","sponsor":"Chia Tai Tianqing Pharmaceutical Group Co., Ltd.","startDate":"2025-12-18","conditions":"Hyperglycemia","enrollment":66},{"nctId":"NCT05644262","phase":"PHASE2","title":"Life's End Benefits of cannaBidiol and tetrahYdrocannabinol","status":"ACTIVE_NOT_RECRUITING","sponsor":"University of Southern California","startDate":"2023-12-18","conditions":"Agitation, Dementia","enrollment":120},{"nctId":"NCT07324434","phase":"PHASE1","title":"A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Oral F-02-2-Na Tablets in Adult Subjects","status":"ENROLLING_BY_INVITATION","sponsor":"Guangdong Hengqin Novagains Biopharmaceutical Co., Ltd.","startDate":"2025-12-15","conditions":"Hyperuricemia With or Without Gout","enrollment":69},{"nctId":"NCT06544733","phase":"PHASE2, PHASE3","title":"Study of Oral Weekly GS-1720 and GS-4182 Versus Biktarvy in People With HIV-1 Who Are Virologically Suppressed","status":"ACTIVE_NOT_RECRUITING","sponsor":"Gilead Sciences","startDate":"2024-08-20","conditions":"HIV-1-Infection","enrollment":675},{"nctId":"NCT07314242","phase":"PHASE2","title":"A Study to Investigate the Biomarkers of Hemay005 in Adult Participants With Moderate to Severe COPD","status":"NOT_YET_RECRUITING","sponsor":"Ganzhou Hemay Pharmaceutical Co., Ltd","startDate":"2026-01-01","conditions":"COPD (Chronic Obstructive Pulmonary Disease)","enrollment":120},{"nctId":"NCT07040969","phase":"PHASE2","title":"Spirulina-Derived Product Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors","status":"RECRUITING","sponsor":"West China Hospital","startDate":"2025-06-27","conditions":"Radiation-induced Oral Mucositis","enrollment":70},{"nctId":"NCT06899230","phase":"PHASE1","title":"Safety, Tolerability, and Pharmacokinetics (PK) of Single and Multiple Ascending Oral Doses of iQ-007","status":"ACTIVE_NOT_RECRUITING","sponsor":"iQure Australia Pty Ltd","startDate":"2025-04-08","conditions":"Drug Resistant Epilepsy, Focal Seizure","enrollment":72},{"nctId":"NCT07285967","phase":"PHASE1","title":"A First-in-Human SAD and MAD Study in Healthy Participants to Evaluate Oral YR011 Tablet","status":"NOT_YET_RECRUITING","sponsor":"Hangzhou Yirui Pharmaceutical Technology Co., Ltd","startDate":"2026-04-01","conditions":"Safety, Tolerability, Pharmacokinetics","enrollment":64},{"nctId":"NCT07300813","phase":"NA","title":"Olistic_2025 for Hair Loss, Hair Growth, and Skin Improvement","status":"ACTIVE_NOT_RECRUITING","sponsor":"Bionos Biotech S.L.","startDate":"2025-10-20","conditions":"Hair Care, Hair Loss, Female Pattern Hair Loss","enrollment":100},{"nctId":"NCT04925752","phase":"PHASE3","title":"Study of Lenacapavir for HIV Pre-Exposure Prophylaxis in People Who Are at Risk for HIV Infection","status":"ACTIVE_NOT_RECRUITING","sponsor":"Gilead Sciences","startDate":"2021-06-28","conditions":"Pre-Exposure Prophylaxis of HIV Infection","enrollment":3292},{"nctId":"NCT02281929","phase":"PHASE3","title":"Efficacy of Antibiotic Therapy in Severe Alcoholic Hepatitis Treated With Prednisolone","status":"COMPLETED","sponsor":"University Hospital, Lille","startDate":"2015-06-13","conditions":"Alcoholic Hepatitis, Alcoholic Liver Disease","enrollment":297},{"nctId":"NCT05288543","phase":"PHASE1","title":"A Study of Orally Administered IPG7236 in Healthy Adult Participants","status":"TERMINATED","sponsor":"Nanjing Immunophage Biotech Co., Ltd","startDate":"2022-04-07","conditions":"Atopic Dermatitis","enrollment":63},{"nctId":"NCT06088784","phase":"PHASE1","title":"A Study Assessing the Safety of Oral ATH-399A in Healthy Adult Participants","status":"COMPLETED","sponsor":"HanAll BioPharma Co., Ltd.","startDate":"2023-09-19","conditions":"Healthy Volunteers","enrollment":76},{"nctId":"NCT05822544","phase":"PHASE1","title":"Phase 1/1b Study of TLC-6740 in Healthy Subjects and Subjects With Obesity, With or Without Diabetes","status":"RECRUITING","sponsor":"OrsoBio, Inc","startDate":"2023-04-22","conditions":"Healthy Subjects, Obesity, Type 2 Diabetes","enrollment":564},{"nctId":"NCT06525389","phase":"PHASE3","title":"Liposomal Amphotericin B and Flucytosine Antifungal Strategy for Talaromycosis (LAmB-FAST)","status":"NOT_YET_RECRUITING","sponsor":"Duke University","startDate":"2026-04-01","conditions":"Talaromycosis","enrollment":428},{"nctId":"NCT07288151","phase":"PHASE2","title":"MDMA-Assisted Massed Exposure Therapy for PTSD","status":"NOT_YET_RECRUITING","sponsor":"Emory University","startDate":"2026-01","conditions":"Post Traumatic Stress Disorder","enrollment":200},{"nctId":"NCT06079775","phase":"PHASE1","title":"P1, DDI & MAD PK and Safety Study of Xeruborbactam Oral Prodrug in Combo With Ceftibuten in Healthy Participants","status":"COMPLETED","sponsor":"Qpex Biopharma, Inc.","startDate":"2024-01-30","conditions":"Bacterial Infections","enrollment":53},{"nctId":"NCT06483789","phase":"PHASE2","title":"Efficacy and Safety of HB-1 for Panic Disorder","status":"RECRUITING","sponsor":"Honeybrains Biotech LLC","startDate":"2024-10-29","conditions":"Panic Disorder, Mental Illness","enrollment":240},{"nctId":"NCT06817031","phase":"PHASE2","title":"Maternal Probiotic Intervention to Improve Gut Health - Trial II - Bangladesh","status":"ENROLLING_BY_INVITATION","sponsor":"International Centre for Diarrhoeal Disease Research, Bangladesh","startDate":"2025-04-20","conditions":"Environmental Enteric Dysfunction","enrollment":144},{"nctId":"NCT07275775","phase":"PHASE1","title":"Single and Multiple Dose and Food Effect Study to Evaluate the Safety, Tolerability and Pharmacokinetics of D-2570 Tablets in Healthy Subjects","status":"COMPLETED","sponsor":"InventisBio Co., Ltd","startDate":"2024-08-13","conditions":"Healthy","enrollment":100},{"nctId":"NCT02408354","phase":"PHASE2","title":"Pilot Study, Comparative, Single-center, Randomized, Crossover, Double-blind, Against Placebo, Testing the Effectiveness of Triheptanoin Oil in Alternating Hemiplegia of Childhood","status":"COMPLETED","sponsor":"Institut National de la Santé Et de la Recherche Médicale, France","startDate":"2015-03-25","conditions":"Alternating Hemiplegia of Childhood","enrollment":10},{"nctId":"NCT06399315","phase":"PHASE1","title":"Study of Single and Multiple Ascending Doses of ZE46-0134 in Healthy Volunteers","status":"COMPLETED","sponsor":"Lomond Therapeutics Holdings, Inc.","startDate":"2023-07-28","conditions":"AML","enrollment":112},{"nctId":"NCT07270042","phase":"NA","title":"Evaluation the Efficacy of Zinc on Botulinum Toxin A Injection","status":"NOT_YET_RECRUITING","sponsor":"Tishreen University","startDate":"2025-12-01","conditions":"Hyperactive Masseter Muscle","enrollment":20},{"nctId":"NCT07260773","phase":"NA","title":"The Effects of Coenzyme Q10 Pretreatment on Ovarian Function and Assisted Reproductive Outcomes in Patients With Ovarian Hyporesponsiveness.","status":"NOT_YET_RECRUITING","sponsor":"Tang-Du Hospital","startDate":"2025-12","conditions":"Ovarian Response","enrollment":128},{"nctId":"NCT05643638","phase":"PHASE2","title":"A Study of CYP-001 in Combination With Corticosteroids in Adults With High-risk aGvHD","status":"RECRUITING","sponsor":"Cynata Therapeutics Limited","startDate":"2024-03-04","conditions":"Graft Versus Host Disease, Acute","enrollment":60},{"nctId":"NCT07262346","phase":"PHASE1","title":"The Phase Ⅰd Clinical Trial of Hydronidone Capsules","status":"NOT_YET_RECRUITING","sponsor":"Beijing Continent Pharmaceutical Co, Ltd.","startDate":"2025-12-05","conditions":"Liver Fibrosis","enrollment":138},{"nctId":"NCT07234448","phase":"NA","title":"Evaluation of the Use of a Probiotic Containing Bifidobacterium Breve PRL2020 in Oral Drops in Preventing Side Effects From Amoxicillin or Amoxicillin/Clavulanic Acid Antibiotic Use","status":"NOT_YET_RECRUITING","sponsor":"Liaquat University of Medical & Health Sciences","startDate":"2025-12-01","conditions":"Antibiotic-associated Diarrhea","enrollment":1000},{"nctId":"NCT06613685","phase":"PHASE2, PHASE3","title":"Study of Oral Weekly GS-1720 and GS-4182 Compared With Biktarvy in People With HIV-1 Who Have Not Been Treated","status":"ACTIVE_NOT_RECRUITING","sponsor":"Gilead Sciences","startDate":"2024-10-21","conditions":"HIV-1-infection","enrollment":675},{"nctId":"NCT04536337","phase":"PHASE1","title":"A Study of ALG-000184 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB Subjects","status":"COMPLETED","sponsor":"Aligos Therapeutics","startDate":"2020-10-22","conditions":"Chronic Hepatitis B","enrollment":165},{"nctId":"NCT05264506","phase":"PHASE3","title":"Contraceptive Efficacy and Safety of NOMAC-E2 Combined Oral Contraceptive","status":"TERMINATED","sponsor":"Organon and Co","startDate":"2022-02-17","conditions":"Contraception","enrollment":3055},{"nctId":"NCT06298383","phase":"NA","title":"The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain","status":"RECRUITING","sponsor":"Cairo University","startDate":"2025-06-15","conditions":"Symptomatic Irreversible Pulpitis","enrollment":120},{"nctId":"NCT07134790","phase":"PHASE2","title":"Maternal Probiotic Intervention to Improve Gut Health - Trial II - Burkina Faso (MPIGH-II)","status":"RECRUITING","sponsor":"University Ghent","startDate":"2025-07-30","conditions":"Environmental Enteric Dysfunction (EED)","enrollment":144},{"nctId":"NCT07043452","phase":"EARLY_PHASE1","title":"Measuring Acute Drug Demand in Humans II","status":"WITHDRAWN","sponsor":"Johns Hopkins University","startDate":"2025-11-15","conditions":"Healthy Volunteers","enrollment":""},{"nctId":"NCT05731544","phase":"PHASE1, PHASE2","title":"Study of BMF-219 in Healthy Adult Subjects and in Adult Subjects With Type 2 Diabetes Mellitus (T2D)","status":"COMPLETED","sponsor":"Biomea Fusion Inc.","startDate":"2022-08-17","conditions":"Type 2 Diabetes Mellitus","enrollment":443},{"nctId":"NCT03754725","phase":"PHASE1, PHASE2","title":"Ferritin and Iron Burden in SAH sIRB","status":"RECRUITING","sponsor":"Duke University","startDate":"2020-10-01","conditions":"SAH, Dementia","enrollment":66},{"nctId":"NCT06528457","phase":"PHASE2","title":"Study to Examine the Effects of Oral Fenretinide","status":"COMPLETED","sponsor":"Island Pharmaceuticals","startDate":"2024-09-05","conditions":"Dengue","enrollment":15},{"nctId":"NCT05846399","phase":"PHASE4","title":"CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)","status":"RECRUITING","sponsor":"University of Missouri-Columbia","startDate":"2023-09-07","conditions":"Cat Bite, Hand Injuries, Arm Injury","enrollment":72},{"nctId":"NCT02897063","phase":"PHASE1","title":"Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure","status":"RECRUITING","sponsor":"Vanderbilt University Medical Center","startDate":"2016-09","conditions":"Autonomic Failure, Pure Autonomic Failure, Multiple System Atrophy","enrollment":34},{"nctId":"NCT05279742","phase":"PHASE1, PHASE2","title":"Enhancing the Natriuretic Peptide System in HFpEF","status":"ENROLLING_BY_INVITATION","sponsor":"Horng Chen","startDate":"2022-11-04","conditions":"Heart Failure With Preserved Ejection Fraction, Chronic Kidney Diseases","enrollment":60},{"nctId":"NCT07207434","phase":"PHASE2","title":"Maternal Probiotic Intervention to Improve Gut Health-Trial II-Pakistan","status":"RECRUITING","sponsor":"Aga Khan University","startDate":"2025-08-30","conditions":"Environmental Enteric Dysfunction (EED), Stunting","enrollment":144},{"nctId":"NCT04442022","phase":"PHASE2, PHASE3","title":"A Study of Rituximab-Gemcitabine-Dexamethasone-Platinum (R-GDP) With or Without Selinexor in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma","status":"RECRUITING","sponsor":"Karyopharm Therapeutics Inc","startDate":"2020-09-03","conditions":"Relapsed/Refractory Diffuse Large B-cell Lymphoma","enrollment":501},{"nctId":"NCT07204171","phase":"PHASE1","title":"Phase 1 Study of Oral MG001","status":"NOT_YET_RECRUITING","sponsor":"National Institute on Drug Abuse (NIDA)","startDate":"2026-02","conditions":"Safety and Tolerability in Healthy Subjects","enrollment":32},{"nctId":"NCT06673667","phase":"PHASE1","title":"First-in-human Study of Orally Administered KT-621 in Healthy Adult Participants","status":"COMPLETED","sponsor":"Kymera Therapeutics, Inc.","startDate":"2024-10-22","conditions":"Healthy Participants Study","enrollment":118},{"nctId":"NCT06363383","phase":"PHASE1","title":"A Phase 1 Study to Evaluate the Safety of an Oral Biologic in Healthy Participants","status":"COMPLETED","sponsor":"Mage Biologics","startDate":"2024-05-09","conditions":"Ulcerative Colitis","enrollment":48},{"nctId":"NCT06072170","phase":"PHASE1","title":"Single Ascending Doses of Kratom in Healthy Nondependent Adults With Opioid Experience","status":"COMPLETED","sponsor":"Altasciences Company Inc.","startDate":"2023-08-16","conditions":"Safety, Pharmacokinetics, Pharmacodynamics","enrollment":40},{"nctId":"NCT04435288","phase":"PHASE3","title":"Spondyloarthritis: Inducing Drug-free Remission by Early TNF-alpha Blockade","status":"ACTIVE_NOT_RECRUITING","sponsor":"University Hospital, Ghent","startDate":"2020-08-24","conditions":"Peripheral Spondyloarthritis","enrollment":90},{"nctId":"NCT07193277","phase":"PHASE4","title":"Butylphthalide for Cognitive Impairment in Elderly Patients With Focal Epilepsy","status":"RECRUITING","sponsor":"First Affiliated Hospital of Wenzhou Medical University","startDate":"2025-09-01","conditions":"Focal Epilepsy, Cognitive Impairment","enrollment":220},{"nctId":"NCT06387966","phase":"PHASE1","title":"A Phase I Clinical Study of Flonoltinib Maleate Tablets in Healthy Subjects","status":"COMPLETED","sponsor":"Chengdu Zenitar Biomedical Technology Co., Ltd","startDate":"2024-03-18","conditions":"Heathly Subjects","enrollment":40},{"nctId":"NCT04255277","phase":"PHASE1","title":"To Study the Effect of Cenerimod on the Electrical Activity of the Heart, in Men and Women. To Study the Effect of Cenerimod on the Use of Oral Contraceptives in Women. To Study the Effect That Charcoal Has on the Elimination of Cenerimod From the Body, in Women and Men.","status":"COMPLETED","sponsor":"Viatris Innovation GmbH","startDate":"2020-01-31","conditions":"Healthy Subjects","enrollment":97},{"nctId":"NCT07178093","phase":"NA","title":"Effects of Antrodia Cinnamomea on the Hepatoma Patients After Transcatheter Hepatic Artery Chemoembolization","status":"RECRUITING","sponsor":"Taichung Tzu Chi Hospital","startDate":"2023-01-01","conditions":"Hepatocellular Carcinoma, Transarterial Chemoembolization","enrollment":60},{"nctId":"NCT00993408","phase":"PHASE2","title":"Study of ACT-293987 (NS-304) in Pulmonary Arterial Hypertension (PAH)","status":"COMPLETED","sponsor":"Actelion","startDate":"2008-04-30","conditions":"Pulmonary Arterial Hypertension","enrollment":43},{"nctId":"NCT00696033","phase":"NA","title":"Exploring the Effects of Diazepam and Lorazepam","status":"COMPLETED","sponsor":"University Hospital, Strasbourg, France","startDate":"2007-07","conditions":"Healthy Subjects","enrollment":22},{"nctId":"NCT02957929","phase":"PHASE1","title":"Safety, Pharmacokinetics, Bioavailability, Food Effect, Drug-Drug Interaction Study of APX001 Administered Orally","status":"COMPLETED","sponsor":"Basilea Pharmaceutica","startDate":"2016-10-31","conditions":"Fungal Infection","enrollment":46},{"nctId":"NCT07162116","phase":"PHASE1","title":"A Study to Evaluate the Effect of XY0206 on the QTc Interval in Chinese Healthy Participants","status":"RECRUITING","sponsor":"Shijiazhuang Yiling Pharmaceutical Co. Ltd","startDate":"2025-07-06","conditions":"Acute Myeloid Leukemia With FLT3/ITD Mutation","enrollment":45},{"nctId":"NCT07146997","phase":"PHASE3","title":"Evaluating the Combined Effect of Oral Premedications on Inferior Alveolar Nerve Block Effectiveness","status":"COMPLETED","sponsor":"Zahoor khan","startDate":"2023-11-23","conditions":"Symptomatic Irreversible Pulpitis","enrollment":96},{"nctId":"NCT05696717","phase":"PHASE3","title":"Phase 3 Efficacy and Durability of Ampreloxetine for the Treatment of Symptomatic nOH in Participants With Multiple System Atrophy","status":"ACTIVE_NOT_RECRUITING","sponsor":"Theravance Biopharma","startDate":"2023-06-27","conditions":"Symptomatic Neurogenic Orthostatic Hypotension, MSA - Multiple System Atrophy","enrollment":102},{"nctId":"NCT06500429","phase":"PHASE2","title":"A Study to Evaluate the Safety and Efficacy of NG101 in Adult Participants Receiving a Glucagon-like Peptide-1 (GLP-1) Agonist","status":"COMPLETED","sponsor":"Neurogastrx, Inc.","startDate":"2024-06-24","conditions":"Overweight and Obesity, Healthy","enrollment":120},{"nctId":"NCT07031388","phase":"NA","title":"Mouthwashes for Gingivitis: Comparing a Hydrogen Peroxide-Hyaluronic Acid Mix, Hyaluronic Acid, and Chlorhexidine, A Triple-Blind Clinical Trial","status":"ACTIVE_NOT_RECRUITING","sponsor":"Ramziyah Hayder Bakr","startDate":"2025-07-01","conditions":"Plaque Induced Gingival Disease","enrollment":80}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Placebo Only Product in Oral Dose Form","genericName":"Placebo Only Product in Oral Dose Form","companyName":"University of Southampton","companyId":"university-of-southampton","modality":"Small molecule","firstApprovalDate":"","aiSummary":"A placebo product contains no active pharmaceutical ingredient and produces therapeutic effects solely through placebo response mechanisms. Used for Clinical trial control comparator (not a therapeutic product).","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}