{"id":"placebo-of-oseltamivir","safety":{"commonSideEffects":[]},"_chembl":null,"_sources":{"trials":{"url":"https://clinicaltrials.gov/search?intr=Placebo of Oseltamivir","method":"api_direct","source":"ClinicalTrials.gov","rawText":"","confidence":1,"sourceType":"ctgov","retrievedAt":"2026-04-20T02:35:25.017315+00:00"},"regulatory.ca":{"url":"","method":"api_direct","source":"Health Canada DPD","rawText":"","confidence":1,"sourceType":"health_canada_dpd","retrievedAt":"2026-04-20T02:35:31.394637+00:00"},"publicationCount":{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=Placebo of Oseltamivir","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-20T02:35:31.818499+00:00"},"crossReferences.chemblId":{"url":"https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL1229/","method":"api_direct","source":"ChEMBL (EMBL-EBI)","rawText":"","confidence":1,"sourceType":"chembl","retrievedAt":"2026-04-20T02:35:39.953824+00:00"}},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Placebos are inert substances used as controls in clinical trials to establish the true efficacy of an active drug by comparison. Any observed effects in placebo groups are attributed to the placebo effect (psychological and contextual factors) rather than direct pharmacological action. In this case, it is a placebo formulation matching the appearance of oseltamivir (an antiviral) but containing no active drug.","oneSentence":"A placebo contains no active pharmaceutical ingredient and produces no pharmacological effect.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:01:17.803Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T02:35:41.545268+00:00","fieldsConflicting":0,"overallConfidence":0.95},"indications":{"approved":[{"name":"Control arm in oseltamivir clinical trials"}]},"trialDetails":[{"nctId":"NCT07357051","phase":"PHASE3","title":"Phase III Clinical Study Evaluating the Safety, Pharmacokinetics, and Efficacy of JKN2301 Dry Suspension in Pediatric Patients Aged 2 to Under 12 Years With Influenza","status":"RECRUITING","sponsor":"Joincare Pharmaceutical Group Industry Co., Ltd","startDate":"2025-11-07","conditions":"Respiratory Viral Infection","enrollment":177},{"nctId":"NCT07095257","phase":"PHASE3","title":"Study to Assess the Safety and Efficacy of ZX-7101A for Oral Suspension in Chinese Pediatric Participants 2 to 11 Years of Age With Influenza","status":"RECRUITING","sponsor":"Nanjing Zenshine Pharmaceuticals","startDate":"2025-10-13","conditions":"Respiratory Viral Infection","enrollment":168},{"nctId":"NCT06507813","phase":"PHASE3","title":"Safety and Efficacy of ADC189 in Children 2-11 Years Old With Influenza","status":"COMPLETED","sponsor":"Jiaxing AnDiCon Biotech Co.,Ltd","startDate":"2024-08-19","conditions":"Influenza Type A, Influenza Type B","enrollment":190},{"nctId":"NCT06669351","phase":"PHASE3","title":"Study to Assess the Safety and Efficacy of ZX-7101A in Children Aged 5-11 Years With Influenza","status":"TERMINATED","sponsor":"Nanjing Zenshine Pharmaceuticals","startDate":"2024-10-31","conditions":"Respiratory Viral Infection","enrollment":98},{"nctId":"NCT05818124","phase":"PHASE1","title":"Efficacy and Safety of Molnupiravir in Healthy Participants Inoculated With Experimental Influenza Virus (MK-4482-019)","status":"COMPLETED","sponsor":"Merck Sharp & Dohme LLC","startDate":"2023-08-21","conditions":"Influenza Infection","enrollment":161},{"nctId":"NCT03787459","phase":"PHASE3","title":"Severe Influenza Trial of ARbidol","status":"COMPLETED","sponsor":"Capital Medical University","startDate":"2019-01-18","conditions":"Influenza","enrollment":200},{"nctId":"NCT05170009","phase":"PHASE2, PHASE3","title":"Baloxavir in Combination With Oseltamivir in Allogenic Bone Marrow Transplant Recipients With Influenza","status":"TERMINATED","sponsor":"Weill Medical College of Cornell University","startDate":"2022-04-22","conditions":"Influenza","enrollment":2},{"nctId":"NCT02342249","phase":"PHASE2","title":"Study of Acute Uncomplicated Seasonal Influenza A in Adult Subjects","status":"COMPLETED","sponsor":"Janssen Research & Development, LLC","startDate":"2014-12-11","conditions":"Influenza A","enrollment":292},{"nctId":"NCT06693362","phase":"PHASE1","title":"A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study to Evaluate the Safety and Efficacy of Uterine Blood Mesenchymal Stem Cells Injection for the Treatment of Severe Pneumonia Caused by Viruses","status":"RECRUITING","sponsor":"Ruijin Hospital","startDate":"2025-01-20","conditions":"Severe Viral Pneumonia(Not Include COVID-19)","enrollment":60},{"nctId":"NCT03900988","phase":"PHASE3","title":"Intravenous N-acetylcysteine and Oseltamivir Versus Oseltamivir in Adults Hospitalized With Influenza and Pneumonia","status":"UNKNOWN","sponsor":"Chinese University of Hong Kong","startDate":"2023-05-08","conditions":"Influenza","enrollment":160},{"nctId":"NCT04683406","phase":"PHASE3","title":"A Study of ZSP1273 Tablets in Patients With Acute Uncomplicated Influenza A","status":"COMPLETED","sponsor":"Guangdong Raynovent Biotech Co., Ltd","startDate":"2020-12-28","conditions":"Influenza A","enrollment":750},{"nctId":"NCT04982913","phase":"PHASE1","title":"Single Dose and Multiple Dose Safety, Tolerability, PK，and Food Effect Study，and Interaction With Oseltamivir Study of HEC116094 in Healthy Adult Subjects","status":"COMPLETED","sponsor":"Sunshine Lake Pharma Co., Ltd.","startDate":"2021-08-24","conditions":"Influenza","enrollment":118},{"nctId":"NCT03212716","phase":"PHASE2","title":"Efficiency of Antagonist Drugs of the Cellular Transcriptomic Signature of Influenza A Virus Infection.","status":"TERMINATED","sponsor":"University Hospital, Lille","startDate":"2017-12-23","conditions":"Flu","enrollment":85},{"nctId":"NCT03040141","phase":"PHASE2","title":"Study of Efficacy and Safety of IV VIS410 Plus Oseltamivir Versus Oseltamivir in Hospitalized Adults With Influenza A","status":"COMPLETED","sponsor":"Visterra, Inc.","startDate":"2018-01-03","conditions":"Influenza A","enrollment":89},{"nctId":"NCT04523090","phase":"PHASE2, PHASE3","title":"Catalysing the Containment of COVID-19","status":"TERMINATED","sponsor":"University of Cape Town","startDate":"2020-08-27","conditions":"COVID-19","enrollment":322},{"nctId":"NCT03684044","phase":"PHASE3","title":"Study to Assess Efficacy and Safety of Baloxavir Marboxil In Combination With Standard-of-Care Neuraminidase Inhibitor In Hospitalized Participants With Severe Influenza","status":"COMPLETED","sponsor":"Hoffmann-La Roche","startDate":"2019-01-08","conditions":"Influenza","enrollment":363},{"nctId":"NCT02927431","phase":"PHASE2","title":"Study to Evaluate the Efficacy and Safety of Danirixin Co-administered With Oseltamivir in the Treatment of Adults Hospitalized With Influenza","status":"TERMINATED","sponsor":"GlaxoSmithKline","startDate":"2017-01-19","conditions":"Virus Diseases","enrollment":10},{"nctId":"NCT03520049","phase":"PHASE3","title":"Proof-of-Concept: A Pilot, Randomized, Double-Blind Study of Oseltamivir Versus Placebo for Immune Thrombocytopenia","status":"UNKNOWN","sponsor":"Unity Health Toronto","startDate":"2016-11","conditions":"Immune Thrombocytopenia","enrollment":30},{"nctId":"NCT03629184","phase":"PHASE3","title":"Study to Assess the Safety, Pharmacokinetics, and Efficacy of Baloxavir Marboxil in Healthy Pediatric Participants With Influenza-Like Symptoms","status":"COMPLETED","sponsor":"Hoffmann-La Roche","startDate":"2018-11-20","conditions":"Influenza","enrollment":173},{"nctId":"NCT02532283","phase":"PHASE2","title":"A Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of JNJ-63623872 in Combination With Oseltamivir in Adult, and Elderly Hospitalized Participants With Influenza A Infection","status":"COMPLETED","sponsor":"Janssen Research & Development, LLC","startDate":"2015-12-11","conditions":"Influenza A Virus","enrollment":102},{"nctId":"NCT03903718","phase":"PHASE2","title":"Evaluation of the Safety and Efficacy of a Monoclonal Antibody to Treat Influenza","status":"WITHDRAWN","sponsor":"MedImmune LLC","startDate":"2020-04-03","conditions":"Influenza","enrollment":""},{"nctId":"NCT02949011","phase":"PHASE3","title":"Study of S-033188 (Baloxavir Marboxil) Compared With Placebo or Oseltamivir in Patients With Influenza at High Risk of Influenza Complications","status":"COMPLETED","sponsor":"Shionogi","startDate":"2017-01-11","conditions":"Influenza","enrollment":2184},{"nctId":"NCT03238612","phase":"PHASE2","title":"Flufenamic Acid for Hospitalised Influenza Infection","status":"UNKNOWN","sponsor":"The University of Hong Kong","startDate":"2018-01-08","conditions":"Influenza A","enrollment":200},{"nctId":"NCT02108366","phase":"PHASE3","title":"Treatment of Severe Influenza A Infection","status":"COMPLETED","sponsor":"The University of Hong Kong","startDate":"2014-03","conditions":"Influenza, Human","enrollment":107},{"nctId":"NCT02469298","phase":"PHASE2","title":"Safety, Tolerability and Clinical Effect of Danirixin in Adults With Influenza","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2015-06-01","conditions":"Virus Diseases","enrollment":45},{"nctId":"NCT02954354","phase":"PHASE3","title":"A Study of S-033188 (Baloxavir Marboxil) Compared With Placebo or Oseltamivir in Otherwise Healthy Patients With Influenza","status":"COMPLETED","sponsor":"Shionogi","startDate":"2016-12-08","conditions":"Influenza","enrollment":1436},{"nctId":"NCT03028909","phase":"PHASE2","title":"Dose Ranging Study to Evaluate the Efficacy and Safety of MEDI8852 in Adults Who Are Hospitalized With Type A Influenza.","status":"WITHDRAWN","sponsor":"MedImmune LLC","startDate":"2017-07-24","conditions":"Influenza - Type A Strains","enrollment":""},{"nctId":"NCT01314911","phase":"NA","title":"Evaluating the Use of Oseltamivir for the Treatment of Influenza in Adults","status":"COMPLETED","sponsor":"National Institute of Allergy and Infectious Diseases (NIAID)","startDate":"2011-04","conditions":"Influenza, Human","enrollment":716},{"nctId":"NCT00803595","phase":"PHASE3","title":"A Multinational Phase III Study of CS-8958 (MARVEL)","status":"COMPLETED","sponsor":"Daiichi Sankyo Co., Ltd.","startDate":"2008-11","conditions":"Influenza, Human","enrollment":1002},{"nctId":"NCT02282384","phase":"PHASE4","title":"An RCT of Oseltamivir in Outpatients With CPD: A Pilot Study.","status":"WITHDRAWN","sponsor":"McMaster University","startDate":"2014-10","conditions":"Pulmonary Disease, Influenza","enrollment":""},{"nctId":"NCT00555893","phase":"NA","title":"Efficacy Study of Early Versus Late Oseltamivir Administration for Treating and Preventing Influenza","status":"COMPLETED","sponsor":"Marshfield Clinic Research Foundation","startDate":"2008-01","conditions":"Influenza","enrollment":194},{"nctId":"NCT01231620","phase":"PHASE3","title":"A Study of Intravenous Zanamivir Versus Oral Oseltamivir in Adults and Adolescents Hospitalized With Influenza","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2011-01-15","conditions":"Influenza, Human","enrollment":626},{"nctId":"NCT00545532","phase":"PHASE3","title":"A Study of Oseltamivir (Tamiflu) for Treatment of Influenza in Immunocompromised Participants.","status":"COMPLETED","sponsor":"Hoffmann-La Roche","startDate":"2008-02-04","conditions":"Influenza, Human","enrollment":228},{"nctId":"NCT02293863","phase":"PHASE2","title":"A Study of MHAA4549A in Combination With Oseltamivir Versus Oseltamivir in Participants With Severe Influenza A Infection","status":"COMPLETED","sponsor":"Genentech, Inc.","startDate":"2015-01-14","conditions":"Influenza","enrollment":168},{"nctId":"NCT02603952","phase":"PHASE1, PHASE2","title":"A Phase 2a to Evaluate the Safety of MEDI8852 in Adults With Uncomplicated Influenza","status":"COMPLETED","sponsor":"MedImmune LLC","startDate":"2015-12-07","conditions":"Influenza","enrollment":126},{"nctId":"NCT00707941","phase":"PHASE3","title":"Oseltamivir Randomised Controlled Efficacy Trial","status":"COMPLETED","sponsor":"International Centre for Diarrhoeal Disease Research, Bangladesh","startDate":"2008-05","conditions":"Influenza, Pneumonia, Lower Respiratory Tract Infection","enrollment":1190},{"nctId":"NCT01610245","phase":"PHASE3","title":"Safety and Efficacy Study of Nitazoxanide in the Treatment of Acute Uncomplicated Influenza","status":"COMPLETED","sponsor":"Romark Laboratories L.C.","startDate":"2013-03","conditions":"Influenza","enrollment":1941},{"nctId":"NCT02561169","phase":"PHASE4","title":"A Trial of Oseltamivir in High-Risk Patients Presenting to the Emergency Department With Influenza","status":"TERMINATED","sponsor":"McMaster University","startDate":"2015-12","conditions":"Influenza","enrollment":1},{"nctId":"NCT01980966","phase":"PHASE2","title":"A Study of MHAA4549A in Healthy Volunteers in an Influenza Challenge Model","status":"COMPLETED","sponsor":"Genentech, Inc.","startDate":"2013-11-25","conditions":"Healthy Volunteer","enrollment":101},{"nctId":"NCT02717754","phase":"PHASE1","title":"A Study to Investigate the Safety, Tolerability, and Pharmacokinetics (PK) of Oseltamivir and Its Carboxylate Metabolite, RO0640802 in Healthy Participants","status":"COMPLETED","sponsor":"Hoffmann-La Roche","startDate":"2009-12","conditions":"Healthy Volunteer","enrollment":99},{"nctId":"NCT00412737","phase":"PHASE4","title":"A Study of Oseltamivir (Tamiflu) for the Seasonal Prophylaxis of Influenza in Immunocompromised Participants","status":"COMPLETED","sponsor":"Hoffmann-La Roche","startDate":"2007-01","conditions":"Influenza","enrollment":477},{"nctId":"NCT02232945","phase":"PHASE4","title":"Banlangen Granules Anti-seasonal Influenza Study","status":"UNKNOWN","sponsor":"Hutchison Whampoa Guangzhou Baiyunshan Chinese Medicine Company Limited","startDate":"2012-04","conditions":"Influenza","enrollment":177},{"nctId":"NCT02662426","phase":"PHASE3","title":"Lingdancao Granules in the Treatment of Seasonal Influenza","status":"UNKNOWN","sponsor":"The First Affiliated Hospital of Guangzhou Medical University","startDate":"2016-04","conditions":"Influenza","enrollment":318},{"nctId":"NCT00453999","phase":"PHASE2","title":"Evaluation of Efficacy and Safety of Peramivir in Adults With Acute Serious or Potentially Life-threatening Influenza","status":"COMPLETED","sponsor":"BioCryst Pharmaceuticals","startDate":"2007-07","conditions":"Influenza","enrollment":137},{"nctId":"NCT02262715","phase":"PHASE1","title":"A Study to Assess the Drug-Drug Interaction Between VX-787 and Oseltamivir","status":"COMPLETED","sponsor":"Janssen Infectious Diseases BVBA","startDate":"2014-07","conditions":"Healthy","enrollment":38},{"nctId":"NCT01690637","phase":"PHASE4","title":"Panama and El Salvador Children's Oseltamivir Study","status":"TERMINATED","sponsor":"Centers for Disease Control and Prevention","startDate":"2012-09","conditions":"Influenza, Human Influenza","enrollment":721},{"nctId":"NCT01146535","phase":"PHASE2","title":"Interferon Alpha Lozenges Plus Oseltamivir for Influenza Treatment","status":"COMPLETED","sponsor":"Ainos, Inc. (f/k/a Amarillo Biosciences Inc.","startDate":"2011-01","conditions":"Influenza A Virus Infection","enrollment":40},{"nctId":"NCT01708369","phase":"PHASE1","title":"Alcohol Inhibits Drug Metabolism by Carboxylesterases","status":"COMPLETED","sponsor":"University of Tennessee","startDate":"2012-02","conditions":"Drug Interactions","enrollment":19},{"nctId":"NCT01032837","phase":"PHASE4","title":"A Study of Tamiflu (Oseltamivir) for Treatment of Influenza With a Focus on (H1N1) 2009 Flu Strain","status":"TERMINATED","sponsor":"Hoffmann-La Roche","startDate":"2009-11","conditions":"Influenza","enrollment":102},{"nctId":"NCT00799760","phase":"PHASE3","title":"Evaluation of Efficacity and Safety of Oseltamivir and Zanamivir","status":"TERMINATED","sponsor":"Assistance Publique - Hôpitaux de Paris","startDate":"2008-12","conditions":"Gastric Influenza","enrollment":541},{"nctId":"NCT00979667","phase":"PHASE3","title":"A Clinical Trial Comparing Oseltamivir With Placebo And Zanamivir With Control As First Line Treatment For Human Swine Influenza Infection","status":"TERMINATED","sponsor":"Chinese University of Hong Kong","startDate":"2009-10","conditions":"Upper Respiratory Tract Infection, Influenza","enrollment":4},{"nctId":"NCT00980109","phase":"PHASE4","title":"Long Term Influenza Prophylaxis With Inhaled Zanamivir or Oral Oseltamivir","status":"COMPLETED","sponsor":"University of Oxford","startDate":"2009-09","conditions":"Influenza","enrollment":390},{"nctId":"NCT01053377","phase":"PHASE4","title":"A Randomised Controlled Trial on the Effect of Post-exposure Oseltamivir Prophylaxis on Influenza Transmission in Nursing Homes","status":"UNKNOWN","sponsor":"National Institute for Public Health and the Environment (RIVM)","startDate":"2009-12","conditions":"Influenza","enrollment":900},{"nctId":"NCT00593502","phase":"PHASE4","title":"Early Oseltamivir Treatment of Influenza in Children 1-3 Years of Age","status":"COMPLETED","sponsor":"Hospital District of Southwestern Finland","startDate":"2008-02","conditions":"Influenza","enrollment":409}],"_emaApprovals":[],"_faersSignals":[],"crossReferences":{"chemblId":"CHEMBL1229"},"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Tamiflu Placebo"],"phase":"marketed","status":"active","brandName":"Placebo of Oseltamivir","genericName":"Placebo of Oseltamivir","companyName":"Chinese University of Hong Kong","companyId":"chinese-university-of-hong-kong","modality":"Small molecule","firstApprovalDate":"","aiSummary":"A placebo contains no active pharmaceutical ingredient and produces no pharmacological effect. Used for Control arm in oseltamivir clinical trials.","enrichmentLevel":3,"visitCount":0,"regulatoryByCountry":[{"country_code":"CA","regulator":"Health Canada","status":"approved","approval_date":null,"mah":"","brand_name_local":"","application_number":""},{"country_code":"US","regulator":"FDA","status":"approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null}],"trialStats":{"total":0,"withResults":0},"validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T02:35:41.545268+00:00","fieldsConflicting":0,"overallConfidence":0.95},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}