{"id":"placebo-matching-seroquel-ir","safety":{"commonSideEffects":[]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Placebo matching formulations are inactive preparations designed to be indistinguishable from the active drug in appearance, taste, and administration to maintain blinding in randomized controlled trials. In this case, it mimics Seroquel IR tablets but contains no active quetiapine ingredient, allowing researchers to isolate the true pharmacological effects of quetiapine from placebo response effects.","oneSentence":"This is a placebo formulation matching the appearance and characteristics of Seroquel IR (quetiapine immediate-release) used as a control in clinical trials.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:01:10.981Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Control arm in clinical trials for conditions treated with Seroquel IR (schizophrenia, bipolar disorder, major depressive disorder)"}]},"trialDetails":[{"nctId":"NCT01213836","phase":"PHASE4","title":"Compare the Effect on Cognitive Functioning of Two Formulations of Seroquel, Seroquel XR and IR in Patients With Stable Schizophrenia","status":"COMPLETED","sponsor":"AstraZeneca","startDate":"2010-11","conditions":"Schizophrenia","enrollment":75}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Placebo matching Seroquel IR","genericName":"Placebo matching Seroquel IR","companyName":"AstraZeneca","companyId":"astrazeneca","modality":"Small molecule","firstApprovalDate":"","aiSummary":"This is a placebo formulation matching the appearance and characteristics of Seroquel IR (quetiapine immediate-release) used as a control in clinical trials. Used for Control arm in clinical trials for conditions treated with Seroquel IR (schizophrenia, bipolar disorder, major depressive disorder).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}