{"id":"placebo-for-mfns","safety":{"commonSideEffects":[{"rate":null,"effect":"No adverse events are expected with a placebo."}]},"_chembl":{"chemblId":"CHEMBL521875","moleculeType":"Small molecule","molecularWeight":"460.53"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"As a placebo, it does not interact with any biological systems or molecular targets. It is used as a control in clinical trials to compare the efficacy of active treatments.","oneSentence":"This drug is a placebo, meaning it has no active therapeutic effect.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:27:13.149Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Mild to moderate menopausal flushing"}]},"trialDetails":[{"nctId":"NCT06834347","phase":"PHASE3","title":"A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps","status":"RECRUITING","sponsor":"Sanofi","startDate":"2025-02-12","conditions":"Chronic Rhinosinusitis With Nasal Polyps","enrollment":210},{"nctId":"NCT06834360","phase":"PHASE3","title":"A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps","status":"RECRUITING","sponsor":"Sanofi","startDate":"2025-02-06","conditions":"Chronic Rhinosinusitis With Nasal Polyps","enrollment":210},{"nctId":"NCT06454240","phase":"PHASE2","title":"A Proof-of-concept Study of Lunsekimig Compared With Placebo in Adults With Chronic Rhinosinusitis With Nasal Polyps","status":"ACTIVE_NOT_RECRUITING","sponsor":"Sanofi","startDate":"2024-07-17","conditions":"Chronic Rhinosinusitis With Nasal Polyps","enrollment":79},{"nctId":"NCT06691113","phase":"PHASE2","title":"A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti--IL-33 mAb) in Participants With Chronic Rhinosinusitis Without Nasal Polyps","status":"ACTIVE_NOT_RECRUITING","sponsor":"Sanofi","startDate":"2024-12-16","conditions":"Chronic Rhinosinusitis Without Nasal Polyps","enrollment":60},{"nctId":"NCT06013241","phase":"PHASE2","title":"A Study of the Efficacy and Safety of Brensocatib in Participants With Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)","status":"COMPLETED","sponsor":"Insmed Incorporated","startDate":"2023-10-30","conditions":"Chronic Rhinosinusitis Without Nasal Polyps","enrollment":288},{"nctId":"NCT04596189","phase":"PHASE4","title":"Dupilumab for Prevention of Recurrence of CRSwNP After ESS","status":"COMPLETED","sponsor":"Centre hospitalier de l'Université de Montréal (CHUM)","startDate":"2021-05-25","conditions":"Chronic Rhinosinusitis With Nasal Polyps","enrollment":30},{"nctId":"NCT00750750","phase":"PHASE2","title":"Effectiveness and Safety of Once or Twice Daily Mometasone Nasal Spray Versus Amoxicillin Versus Placebo for Treatment of Acute Rhinosinusitis (Study P02683)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2003-01-01","conditions":"Acute Rhinosinusitis","enrollment":981},{"nctId":"NCT00731185","phase":"PHASE3","title":"Mometasone Furoate Nasal Spray for Treatment of Nasal Polyposis After Surgery (Study P03218)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2003-09-01","conditions":"Nasal Polyps","enrollment":162},{"nctId":"NCT00751075","phase":"PHASE3","title":"Effectiveness and Safety of Once or Twice Daily Mometasone Nasal Spray Versus Amoxicillin Versus Placebo for Treatment of Acute Rhinosinusitis (Phase 3 Study)(Study P02692)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2003-12-01","conditions":"Acute Rhinosinusitis","enrollment":981},{"nctId":"NCT01135134","phase":"PHASE3","title":"Multicenter, Double-blind, Randomized, Placebo-controlled Study of Mometasone Furoate Nasal Spray in Pediatric Subjects With Perennial Allergic Rhinitis (Study P06332)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2010-06","conditions":"Rhinitis, Allergic, Perennial","enrollment":333},{"nctId":"NCT00732381","phase":"PHASE3","title":"Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05529)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2008-08","conditions":"Allergic Rhinitis","enrollment":351},{"nctId":"NCT00733005","phase":"PHASE3","title":"Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05528)(COMPLETED)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2008-07","conditions":"Allergic Rhinitis","enrollment":324},{"nctId":"NCT01386125","phase":"PHASE3","title":"A Study of the Effectiveness and Safety of Mometasone Furoate Nasal Spray (MFNS, SCH 032088) for the Treatment of Nasal Polyps (P05604)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2011-06","conditions":"Nasal Polyps","enrollment":748},{"nctId":"NCT00423176","phase":"PHASE3","title":"The Study of Nasonex® Compared With Placebo for the Relief of Symptoms Associated With Acute Bacterial Sinusitis When Used With Antibiotics (Study P04824AM3)","status":"TERMINATED","sponsor":"Organon and Co","startDate":"2006-12","conditions":"Sinusitis","enrollment":237},{"nctId":"NCT00378378","phase":"PHASE3","title":"Study of Nasonex® for the Treatment of Nasal Polyps in Pediatric Subjects Between Ages of 6 and Less Than 18 Years Old (P04292)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2006-07","conditions":"Nasal Polyps","enrollment":127},{"nctId":"NCT03879772","phase":"PHASE3","title":"Dose-Ranging Study of Mometasone Furoate (MK-0887/SCH 032088) Nasal Spray in the Treatment of Children (Ages 6-11) With Seasonal Allergic Rhinitis (C95-161)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"1996-03-12","conditions":"Rhinitis, Allergic, Seasonal","enrollment":679},{"nctId":"NCT03855228","phase":"PHASE3","title":"Safety and Efficacy of Mometasone Furoate Nasal Spray With the Addition of Loratadine Versus Placebo in Participants With Seasonal Allergic Rhinitis (C94-145)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"1995-03-01","conditions":"Rhinitis, Allergic","enrollment":704},{"nctId":"NCT00491504","phase":"PHASE4","title":"This Study Contains an Active Drug Treatment Group With Mometasone Furoate Nasal Spray and a Placebo (Dummy) Treatment Group for Seasonal Allergic Rhinitis (SAR). (Study P05073)(COMPLETED)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2007-02","conditions":"Seasonal Allergic Rhinitis","enrollment":310},{"nctId":"NCT00728416","phase":"PHASE3","title":"Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05583)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2008-08","conditions":"Allergic Rhinitis","enrollment":333},{"nctId":"NCT00358527","phase":"PHASE4","title":"Mometasone Furoate on Sleep Disturbances in Subjects With Seasonal Allergic Rhinitis (Study P04608) (COMPLETED)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2006-05","conditions":"Seasonal Allergic Rhinitis","enrollment":401},{"nctId":"NCT03401229","phase":"PHASE3","title":"Efficacy and Safety Study of Benralizumab for Patients With Severe Nasal Polyposis","status":"COMPLETED","sponsor":"AstraZeneca","startDate":"2018-01-15","conditions":"Nasal Polyposis","enrollment":413},{"nctId":"NCT02898454","phase":"PHASE3","title":"Controlled Clinical Study of Dupilumab in Patients With Nasal Polyps","status":"COMPLETED","sponsor":"Sanofi","startDate":"2016-11-28","conditions":"Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP)","enrollment":448},{"nctId":"NCT02912468","phase":"PHASE3","title":"A Controlled Clinical Study of Dupilumab in Patients With Bilateral Nasal Polyps","status":"COMPLETED","sponsor":"Sanofi","startDate":"2016-12-05","conditions":"Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP)","enrollment":276},{"nctId":"NCT01920893","phase":"PHASE2","title":"An Evaluation of Dupilumab in Patients With Nasal Polyposis And Chronic Symptoms Of Sinusitis","status":"COMPLETED","sponsor":"Sanofi","startDate":"2013-08","conditions":"Nasal Polyps","enrollment":60},{"nctId":"NCT00491374","phase":"PHASE4","title":"Study of Nasonex® in Improving Sleep Disturbances Related to Perennial Allergic Rhinitis (Study P04909)(TERMINATED)","status":"TERMINATED","sponsor":"Schering-Plough","startDate":"2006-09","conditions":"Perennial Allergic Rhinitis","enrollment":""}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":53,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Placebo for MFNS","genericName":"Placebo for MFNS","companyName":"Organon and Co","companyId":"organon-and-co","modality":"Small molecule","firstApprovalDate":"","aiSummary":"This drug is a placebo, meaning it has no active therapeutic effect. Used for Mild to moderate menopausal flushing.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}