{"id":"placebo-for-krg","safety":{"commonSideEffects":[{"rate":null,"effect":"Nocebo effects (adverse expectations)"},{"rate":null,"effect":"Minimal direct adverse events"}]},"_chembl":{"chemblId":"CHEMBL521875","moleculeType":"Small molecule","molecularWeight":"460.53"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Placebo works via psychological and neurobiological mechanisms including expectation, conditioning, and activation of endogenous pain-relief and healing pathways. The effect is particularly pronounced in conditions with subjective symptom components such as pain, nausea, and fatigue. While placebo has no direct molecular target, it can produce measurable physiological changes through mind-body interactions.","oneSentence":"Placebo produces therapeutic effects through patient expectation and the psychobiological placebo response, without active pharmacological ingredients.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:42:05.191Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"KRG (indication not specified; likely a clinical trial or institutional code)"}]},"trialDetails":[{"nctId":"NCT05480774","phase":"PHASE1","title":"Effect of Red Ginseng Extract on Changes in Indicators of Immune Function in Vietnamese Healthy Volunteers","status":"COMPLETED","sponsor":"Centre of Clinical Pharmacology, Hanoi Medical University","startDate":"2022-08-06","conditions":"Healthy","enrollment":101},{"nctId":"NCT03983408","phase":"NA","title":"Impact of Korean Red Ginseng on Fatigue in Patients With Rheumatic Disease","status":"UNKNOWN","sponsor":"Hanyang University","startDate":"2019-06-17","conditions":"Sjögren's Syndrome, Rheumatic Diseases, Korean Red Ginseng","enrollment":120},{"nctId":"NCT02204826","phase":"PHASE4","title":"Effects of Korean Red Ginseng on Semen Parameters in Male Infertility Patients: a Randomized, Placebo-controlled, Double-blind Clinical Study","status":"COMPLETED","sponsor":"Pusan National University Hospital","startDate":"2011-04","conditions":"Male Infertility","enrollment":80},{"nctId":"NCT00728221","phase":"PHASE2","title":"Evaluation and Standardization of Ginseng and it's Components for Blood Pressure Regulation","status":"COMPLETED","sponsor":"Unity Health Toronto","startDate":"2007-11","conditions":"Hypertension, Blood Pressure, Endothelial Function","enrollment":17},{"nctId":"NCT02331589","phase":"PHASE4","title":"Anti-fatigue Effect of Korean Red Ginseng in Patients With Non-alcoholic Hepatitis","status":"COMPLETED","sponsor":"Chuncheon Sacred Heart Hospital","startDate":"2011-08","conditions":"Fatigue","enrollment":75},{"nctId":"NCT02211352","phase":"PHASE2","title":"Effect of Korean Red Ginseng on Central Blood Pressure in Patient With Essential Hypertension","status":"COMPLETED","sponsor":"Daegu Catholic University Medical Center","startDate":"2012-05","conditions":"Hypertension","enrollment":58},{"nctId":"NCT01478009","phase":"PHASE2, PHASE3","title":"Efficacy of an Extract of Concentrated Korean Red Ginseng for Preventing Upper Respiratory Tract Infections","status":"COMPLETED","sponsor":"Chonbuk National University Hospital","startDate":"2010-11","conditions":"Healthy Subjects","enrollment":100}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":52,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Placebo"],"phase":"marketed","status":"active","brandName":"Placebo (for KRG)","genericName":"Placebo (for KRG)","companyName":"Chuncheon Sacred Heart Hospital","companyId":"chuncheon-sacred-heart-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Placebo produces therapeutic effects through patient expectation and the psychobiological placebo response, without active pharmacological ingredients. Used for KRG (indication not specified; likely a clinical trial or institutional code).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}