{"id":"pivampicillin","rwe":[{"pmid":"33888153","year":"2021","title":"Helicobacter cinaedi bacteraemia secondary to enterocolitis in an immunocompetent patient.","finding":"","journal":"Gut pathogens","studyType":"Clinical Study"},{"pmid":"33873191","year":"2021","title":"Intradermal Testing Identifies 1 in 4 Patients with Nonimmediate Penicillin Allergy.","finding":"","journal":"International archives of allergy and immunology","studyType":"Clinical Study"},{"pmid":"32115780","year":"2020","title":"Identification of functional circRNA/miRNA/mRNA regulatory network for exploring prospective therapy strategy of colorectal cancer.","finding":"","journal":"Journal of cellular biochemistry","studyType":"Clinical Study"},{"pmid":"31260651","year":"2019","title":"In utero exposure to antibiotics and risk of congenital malformations: a population-based study.","finding":"","journal":"American journal of obstetrics and gynecology","studyType":"Clinical Study"},{"pmid":"30791432","year":"2019","title":"Machine Learning Approach for Determining the Formation of β-Lactam Antibiotic Complexes with Cyclodextrins Using Multispectral Analysis.","finding":"","journal":"Molecules (Basel, Switzerland)","studyType":"Clinical Study"}],"tags":[{"label":"pivampicillin","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"J01CA02","category":"atc"},{"label":"Active","category":"status"},{"label":"Anti-Bacterial Agents","category":"pharmacology"},{"label":"Anti-Infective Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"pivaloylampicillin","offLabel":[],"synonyms":["pivampicillin","pivaloylampicillin","pivaloyloxymethyl ampicillinate","ampicillin pivaloyloxymethyl ester"],"timeline":[],"approvals":[],"brandName":"Pivaloylampicillin","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"pivampicillin","explanation":"Imagine the bacterial cell wall as a brick wall. 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This prevents the bacteria from growing and multiplying, ultimately leading to the death of the bacterial cell.","oneSentence":"Pivampicillin works by inhibiting bacterial cell wall synthesis, ultimately leading to the death of the bacterial cell.","technicalDetail":"Pivampicillin exerts its antibacterial effect by inhibiting the transpeptidase enzymes responsible for cross-linking peptidoglycan chains in the bacterial cell wall, ultimately leading to cell lysis and 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