{"id":"piritramid-analgetic","safety":{"commonSideEffects":[{"rate":null,"effect":"Respiratory depression"},{"rate":null,"effect":"Nausea and vomiting"},{"rate":null,"effect":"Dizziness"},{"rate":null,"effect":"Constipation"},{"rate":null,"effect":"Sedation"}]},"_chembl":{"chemblId":"CHEMBL559288","moleculeType":"Small molecule","molecularWeight":"430.60"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Piritramid acts as a mu opioid receptor agonist, similar to morphine and other opioids. By binding to mu receptors in the brain and spinal cord, it modulates pain perception and transmission, providing potent analgesia. It is used primarily for moderate to severe acute pain management.","oneSentence":"Piritramid is a synthetic opioid agonist that binds to mu opioid receptors in the central nervous system to produce analgesia.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:00:25.529Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Moderate to severe acute pain"},{"name":"Postoperative pain"}]},"trialDetails":[{"nctId":"NCT04665531","phase":"NA","title":"Postoperative Analgesia With a Catheter Under the Erector Spinae Muscle for Videothoracoscopic Lung Surgery","status":"COMPLETED","sponsor":"Surgery Bitenc","startDate":"2020-02-19","conditions":"Neoplasm of Lung, Thoracic Surgery, Video-Assisted","enrollment":50},{"nctId":"NCT03355352","phase":"","title":"Observational Study of Analgesia and Cost-efficiency of Analgetic Medication Pumps (Zalviso and PCA-syringe Pump (PCA=Patient Controlled Analgesia)) After Urogenital Intervention at the Clinical Daily Routine","status":"UNKNOWN","sponsor":"University Hospital Tuebingen","startDate":"2017-11-01","conditions":"Analgesic Quality, Mobility","enrollment":100},{"nctId":"NCT00188227","phase":"PHASE4","title":"Comparison of Three Different Pain and Anxiety Reducing Methods in Adult Patients Undergoing Bone Marrow Puncture","status":"COMPLETED","sponsor":"Technische Universität Dresden","startDate":"2001-09","conditions":"Patients Undergoing Puncture of the Bone Marrow","enrollment":748}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":13,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Piritramid (analgetic)","genericName":"Piritramid (analgetic)","companyName":"Technische Universität Dresden","companyId":"technische-universit-t-dresden","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Piritramid is a synthetic opioid agonist that binds to mu opioid receptors in the central nervous system to produce analgesia. Used for Moderate to severe acute pain, Postoperative pain.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}