{"id":"pipethanate","rwe":[{"pmid":"1360473","year":"1992","title":"Determination of diphenylmethane antihistaminic drugs and their analogues in body fluids by gas chromatography with surface ionization detection.","finding":"","journal":"Journal of chromatography","studyType":"Clinical Study"},{"pmid":"1036888","year":"1976","title":"Therapeutic effects of some cholinolytics in organophosphate intoxications.","finding":"","journal":"Archives of toxicology","studyType":"Clinical Study"},{"pmid":"4477099","year":"1974","title":"[Absorption, distribution and excretion of C14-pipethanate hydrochloride].","finding":"","journal":"Nihon yakurigaku zasshi. Folia pharmacologica Japonica","studyType":"Clinical Study"},{"pmid":"5170094","year":"1971","title":"[Studies on pharmacological effect of pipethanate. II. Effect of pipethanate on respiration, circulation system and smooth muscle].","finding":"","journal":"Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences","studyType":"Clinical Study"},{"pmid":"5170093","year":"1971","title":"[Studies on pharmacological effect of pipethanate. I. Effect of pipethanate on central nervous system].","finding":"","journal":"Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"piperilate","offLabel":[],"synonyms":["piperilate","pipethanate","pipethanate ethobromide","pipethanate hydrochloride","pipethanate HCl"],"timeline":[],"approvals":[],"brandName":"Piperilate","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells have locks on them, and piperilate is a key that fits into one of those locks. When it binds, it changes the way the lock works, which can help treat a particular condition. This is a simplified explanation of how piperilate works at a molecular level.","oneSentence":"Piperilate works by binding to a specific target, altering its function to produce a therapeutic effect.","technicalDetail":"Piperilate's mechanism of action involves reversible binding to a specific protein target, leading to a downstream effect that results in its therapeutic benefit."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2191","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=pipethanate","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:20:55.928002","biosimilars":[],"competitors":[],"genericName":"pipethanate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"018262","UNII":"P32MG14U83","CHEBI":"CHEBI:135438","INN_ID":"930","UMLSCUI":"C0071117","ChEMBL_ID":"CHEMBL1722893","KEGG_DRUG":"D01521","DRUGBANK_ID":"DB15888","PUBCHEM_CID":"20674","SNOMEDCT_US":"703556003","SECONDARY_CAS_RN":"23182-46-9"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":5,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"1992 Oct 23","pmid":"1360473","title":"Determination of diphenylmethane antihistaminic drugs and their analogues in body fluids by gas chromatography with surface ionization detection.","journal":"Journal of chromatography"},{"date":"1976 Oct 28","pmid":"1036888","title":"Therapeutic effects of some cholinolytics in organophosphate intoxications.","journal":"Archives of toxicology"},{"date":"1974 Sep","pmid":"4477099","title":"[Absorption, distribution and excretion of C14-pipethanate hydrochloride].","journal":"Nihon yakurigaku zasshi. Folia pharmacologica Japonica"},{"date":"1971","pmid":"5170094","title":"[Studies on pharmacological effect of pipethanate. II. Effect of pipethanate on respiration, circulation system and smooth muscle].","journal":"Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences"},{"date":"1971","pmid":"5170093","title":"[Studies on pharmacological effect of pipethanate. I. Effect of pipethanate on central nervous system].","journal":"Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Piperilate (pipethanate) is a small molecule modality with unknown target and drug class. Its commercial status is unclear, and it is not known whether it is FDA approved or off-patent. The approved indications for piperilate are also unknown. Further information on its pharmacokinetics, such as half-life and bioavailability, is not available. As a result, key safety considerations and generic manufacturers are also unknown.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}