{"id":"pifarnine","rwe":[{"pmid":"553812","year":"1979","title":"Absorption, distribution and excretion of pifarnine, a novel antiulcer compound. Labelled with 14C.","finding":"","journal":"Il Farmaco; edizione pratica","studyType":"Clinical Study"},{"pmid":"540480","year":"1979","title":"[Gastric anti-secretory activity of pifarnine. Preliminary clinical study].","finding":"","journal":"La Clinica terapeutica","studyType":"Clinical Study"},{"pmid":"378690","year":"1979","title":"[Therapeutical prospects of a piperonylpiperazine derivative (Pifarnine) in gastroduodenal diseases in the aged].","finding":"","journal":"Il Farmaco; edizione pratica","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"pifazin","offLabel":[],"synonyms":["U-27","pifarnine","pifazin"],"timeline":[],"approvals":[],"brandName":"Pifazin","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells are like a city with many different buildings. Pifarnine is like a key that fits into a specific lock on one of those buildings, allowing it to work properly and helping to treat a medical condition. This is a simplified explanation of how Pifarnine might work, but the actual details are more complex and involve specific biological molecules.","oneSentence":"Pifarnine works by binding to specific biological molecules to produce a therapeutic effect.","technicalDetail":"Pifarnine's exact mechanism of action is unknown, but as a small molecule, it is likely to work by interacting with specific enzymes, receptors, or other biological molecules to produce a therapeutic effect."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3470","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=PIFARNINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:20:29.352923","biosimilars":[],"competitors":[],"genericName":"pifarnine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"3W85193GZ4","CHEBI":"CHEBI:135687","INN_ID":"4080","UMLSCUI":"C0071052","ChEMBL_ID":"CHEMBL2105232","KEGG_DRUG":"D05477","PUBCHEM_CID":"6436032","MESH_SUPPLEMENTAL_RECORD_UI":"C008002"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"1979 Dec","pmid":"553812","title":"Absorption, distribution and excretion of pifarnine, a novel antiulcer compound. Labelled with 14C.","journal":"Il Farmaco; edizione pratica"},{"date":"1979 Oct 31","pmid":"540480","title":"[Gastric anti-secretory activity of pifarnine. Preliminary clinical study].","journal":"La Clinica terapeutica"},{"date":"1979 Feb","pmid":"378690","title":"[Therapeutical prospects of a piperonylpiperazine derivative (Pifarnine) in gastroduodenal diseases in the aged].","journal":"Il Farmaco; edizione pratica"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Pifazin is a small molecule. It is also known by the synonyms Pifarnina, Pifarnine, and Pifarnine.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}