{"id":"picosalax-plus-bisacodyl","safety":{"commonSideEffects":[{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Abdominal discomfort"},{"rate":null,"effect":"Vomiting"},{"rate":null,"effect":"Dehydration"},{"rate":null,"effect":"Electrolyte imbalance"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Picosalax is an osmotic laxative containing sodium picosulfate, magnesium oxide, and citric acid that draws water into the bowel lumen to soften stool and increase intestinal motility. Bisacodyl is a stimulant laxative that directly stimulates colonic muscle contractions. Together, they provide enhanced bowel cleansing through complementary mechanisms—osmotic fluid retention and direct muscular stimulation.","oneSentence":"Picosalax plus bisacodyl is a bowel preparation combination that uses osmotic laxatives and a stimulant laxative to cleanse the colon by drawing fluid into the intestines and promoting peristalsis.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:35:57.674Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Bowel cleansing prior to colonoscopy"},{"name":"Bowel cleansing prior to other gastrointestinal procedures"}]},"trialDetails":[{"nctId":"NCT01655095","phase":"PHASE3","title":"Improving Bowel Preparation for the Colon Capsule","status":"COMPLETED","sponsor":"Queen's University","startDate":"2012-07","conditions":"Quality of Bowel Preparation for the Colon Capsule, Colon Capsule Completion Rates, Colon Capsule Polyp Detection","enrollment":20},{"nctId":"NCT00410215","phase":"PHASE4","title":"A Randomized Controlled Trial Comparing Picosalax and Oral Sodium Phosphate for Colon Cleansing Prior to Colonoscopy","status":"COMPLETED","sponsor":"Queen's University","startDate":"2006-02","conditions":"Colonoscopy","enrollment":315}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"picosalax plus bisacodyl","genericName":"picosalax plus bisacodyl","companyName":"Queen's University","companyId":"queen-s-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Picosalax plus bisacodyl is a bowel preparation combination that uses osmotic laxatives and a stimulant laxative to cleanse the colon by drawing fluid into the intestines and promoting peristalsis. Used for Bowel cleansing prior to colonoscopy, Bowel cleansing prior to other gastrointestinal procedures.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}