{"id":"picodralazine","rwe":[],"tags":[{"label":"picodralazine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"C02LG03","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["picodralazine","picodralazine hydrochloride","picodralazine HCl"],"offLabel":[],"synonyms":["picodralazine","picodralazine hydrochloride","picodralazine HCl"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"picodralazine","explanation":"Imagine your body's cells have locks on them, and these locks need a specific key to open. Picodralazine is like a key that fits into one of these locks, but we don't know which lock it is yet. By fitting into the lock, it may help to regulate the activity of the cells.","oneSentence":"Picodralazine is thought to work by modulating a specific target, although this target has not been identified.","technicalDetail":"Picodralazine is a small molecule that interacts with a specific protein or receptor, although the exact nature of this interaction is unknown."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4689","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=PICODRALAZINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:19:52.991798","_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T11:10:42.411683+00:00","fieldsConflicting":0,"overallConfidence":0.95},"biosimilars":[],"competitors":[{"drugName":"hydralazine","drugSlug":"hydralazine","fdaApproval":"1953-01-15","genericCount":44,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"genericName":"picodralazine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"hydralazine","brandName":"hydralazine","genericName":"hydralazine","approvalYear":"1953","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"O9D004V63I","CHEBI":"CHEBI:136022","INN_ID":"2405","UMLSCUI":"C1882375","ChEMBL_ID":"CHEMBL1968696","PUBCHEM_CID":"71890"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"C02LG03","allCodes":["C02LG03","C02LG73"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"PICODRALAZINE","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Picodralazine is a small molecule drug in the picodralazine class, but its target and mechanism of action are unknown. Its commercial status and approved indications are also unclear. As a result, there is limited information available on its safety profile, pharmacokinetics, and generic availability. Further research is needed to fully understand this medication. Its development history is also unclear.","enrichmentLevel":5,"visitCount":0,"trialStats":{"total":0,"withResults":0},"validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T11:10:42.411683+00:00","fieldsConflicting":0,"overallConfidence":0.95},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}