{"id":"piberaline","rwe":[{"pmid":"12015268","year":"2002","title":"Studies on the metabolism and toxicological detection of the new designer drug N-benzylpiperazine in urine using gas chromatography-mass spectrometry.","finding":"","journal":"Journal of chromatography. B, Analytical technologies in the biomedical and life sciences","studyType":"Clinical Study"},{"pmid":"10915973","year":"2000","title":"[Synthesis and antidepressive activity study of aryl and heteroaryl carboxamides of benzylpiperazine].","finding":"","journal":"Annales pharmaceutiques francaises","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["piberaline"],"offLabel":[],"synonyms":["piberaline"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells are like a complex orchestra. Piberaline is like a conductor that tries to lead the cells to work together in a specific way, but we don't know which notes it's playing or how it's affecting the overall performance. This is a simplified explanation of how Piberaline might work, but the actual process is much more complex and not fully understood.","oneSentence":"Piberaline works by interacting with specific biological pathways, but the exact mechanism is unknown.","technicalDetail":"Piberaline's mechanism of action is unknown, but as a small molecule, it is likely to work by binding to specific receptors or enzymes, altering the activity of downstream signaling pathways, and ultimately affecting cellular function."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3466","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=PIBERALINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:19:48.822753","_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T08:51:04.941052+00:00","fieldsConflicting":0,"overallConfidence":0.95},"biosimilars":[],"competitors":[],"genericName":"piberaline","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"8M09P36809","INN_ID":"4240","UMLSCUI":"C2347511","ChEMBL_ID":"CHEMBL2105223","PUBCHEM_CID":"65975"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2002 Jun 15","pmid":"12015268","title":"Studies on the metabolism and toxicological detection of the new designer drug N-benzylpiperazine in urine using gas chromatography-mass spectrometry.","journal":"Journal of chromatography. B, Analytical technologies in the biomedical and life sciences"},{"date":"2000 Jul","pmid":"10915973","title":"[Synthesis and antidepressive activity study of aryl and heteroaryl carboxamides of benzylpiperazine].","journal":"Annales pharmaceutiques francaises"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"PIBERALINE","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Piberaline is a small molecule drug with unknown target and drug class. Its commercial status is unclear, and it has not been approved by the FDA for any indications. As a small molecule, it is likely to work by interacting with specific biological pathways, but the exact mechanism is unknown. Further research is needed to determine its efficacy and safety profile. Piberaline's development and ownership history are also unclear.","enrichmentLevel":5,"visitCount":1,"trialStats":{"total":0,"withResults":0},"validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T08:51:04.941052+00:00","fieldsConflicting":0,"overallConfidence":0.95},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}