{"id":"phenylethanolamine","rwe":[],"tags":[{"label":"phenylethanolamine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"apophedrin","offLabel":[],"synonyms":["bisnorephedrin","norphedrin","apophedrin","phenylethanolamine","phenethanolamine"],"timeline":[],"approvals":[],"brandName":"Apophedrin","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"phenylethanolamine","explanation":"Imagine your brain is a busy city, and neurotransmitters are like messengers that help different parts of the city communicate with each other. Apophedrin is believed to help increase the number of these messengers being sent, which can help improve communication between different parts of the brain.","oneSentence":"Apophedrin is thought to work by stimulating the release of certain neurotransmitters in the brain.","technicalDetail":"Phenylethanolamine is a sympathomimetic agent that may act as a norepinephrine releaser, increasing the concentration of this neurotransmitter in the synaptic cleft and enhancing its effects on the postsynaptic neuron."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3460","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=phenylethanolamine","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:19:03.339608","biosimilars":[],"competitors":[],"genericName":"phenylethanolamine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"2P4Y56479O","CHEBI":"CHEBI:16343","UMLSCUI":"C0000289","ChEMBL_ID":"CHEMBL224526","PUBCHEM_CID":"1000"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1584,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Apophedrin is a small molecule with a structure similar to catecholamine neurotransmitters such as dopamine, norepinephrine, and epinephrine. Its exact clinical uses are not specified in the provided facts, but it is classified as a trace amine with a β-hydroxylated phenethylamine structure.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}