{"id":"phenyl-acetylsalicylate","rwe":[{"pmid":"9485524","year":"1997","title":"Inhibitory actions of ONO-3708 on the stretch-induced contraction potentiated by hemolysate/oxyhemoglobin studied in dog cerebral artery.","finding":"","journal":"Research communications in molecular pathology and pharmacology","studyType":"Clinical Study"},{"pmid":"1568532","year":"1992","title":"Ionic, electrical, and secretory effects of inhibitors of arachidonic acid metabolism in mouse pancreatic beta-cells.","finding":"","journal":"Diabetes","studyType":"Clinical Study"},{"pmid":"2575401","year":"1989","title":"Benorylate hydrolysis by human plasma and human liver.","finding":"","journal":"British journal of clinical pharmacology","studyType":"Clinical Study"},{"pmid":"3672425","year":"1987","title":"Increased aggregation and secretion responses of human platelets when loaded with the calcium fluorescent probes quin2 and fura-2.","finding":"","journal":"Thrombosis and haemostasis","studyType":"Clinical Study"},{"pmid":"2820213","year":"1987","title":"Copper complexes of non-steroidal antiinflammatory agents: analgesic activity and possible opioid receptor activation.","finding":"","journal":"Agents and actions","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"phennin","offLabel":[],"synonyms":["phenyl acetylsalicylate","acetylphenylsalicylate","acetylsalol","aspirin phenyl ester","phennin","vesipyrin"],"timeline":[],"approvals":[],"brandName":"Phennin","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Think of prostaglandins like messengers that tell your body to feel pain and become inflamed. Phennin blocks these messengers, which helps to reduce pain and inflammation. This is similar to how aspirin works, but Phennin is a different molecule with potentially different effects.","oneSentence":"Phennin works by inhibiting the production of prostaglandins, which are hormone-like substances that cause pain and inflammation.","technicalDetail":"Phennin exerts its effects through the inhibition of cyclooxygenase enzymes (COX-1 and COX-2), which are responsible for the conversion of arachidonic acid to prostaglandins."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3443","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=phenyl acetylsalicylate","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:18:51.978461","biosimilars":[],"competitors":[],"genericName":"phenyl acetylsalicylate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"7QP16N8ZNA","CHEBI":"CHEBI:135050","PUBCHEM_CID":"67256"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":6,"therapeuticAreas":["Pain"],"biosimilarFilings":[],"recentPublications":[{"date":"1997 Dec","pmid":"9485524","title":"Inhibitory actions of ONO-3708 on the stretch-induced contraction potentiated by hemolysate/oxyhemoglobin studied in dog cerebral artery.","journal":"Research communications in molecular pathology and pharmacology"},{"date":"1992 May","pmid":"1568532","title":"Ionic, electrical, and secretory effects of inhibitors of arachidonic acid metabolism in mouse pancreatic beta-cells.","journal":"Diabetes"},{"date":"1989 Dec","pmid":"2575401","title":"Benorylate hydrolysis by human plasma and human liver.","journal":"British journal of clinical pharmacology"},{"date":"1987 Aug 4","pmid":"3672425","title":"Increased aggregation and secretion responses of human platelets when loaded with the calcium fluorescent probes quin2 and fura-2.","journal":"Thrombosis and haemostasis"},{"date":"1987 Jun","pmid":"2820213","title":"Copper complexes of non-steroidal antiinflammatory agents: analgesic activity and possible opioid receptor activation.","journal":"Agents and actions"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Phennin (phenyl acetylsalicylate) is a small molecule drug with unknown target and drug class. Its commercial status is unclear, and it is not known whether it is FDA approved or off-patent. The approved indications for Phennin are also unknown. Further research is needed to determine its key safety considerations and pharmacokinetic properties. As a result, Phennin remains a relatively understudied compound.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}