{"id":"phenolsulfonphthalein","rwe":[{"pmid":"40324845","year":"2025","title":"Investigation of new non-toxic inhibitors of fibril formation and preservatives for insulin preparations its analogues.","finding":"","journal":"Advances in protein chemistry and structural biology","studyType":"Clinical Study"},{"pmid":"39705742","year":"2025","title":"Evaluation of prevalence, risk factors, and therapeutic approach for subclinical endometritis and oviductal occlusion in repeat breeder Holstein cattle.","finding":"","journal":"Research in veterinary science","studyType":"Clinical Study"},{"pmid":"35351207","year":"2022","title":"Voriconazole injection may induce delayed methotrexate excretion: a case report and experimental study.","finding":"","journal":"Journal of pharmaceutical health care and sciences","studyType":"Clinical Study"},{"pmid":"35299026","year":"2022","title":"Phenolsulfonphthalein as a surrogate substrate to assess altered function of the prostaglandin transporter SLCO2A1.","finding":"","journal":"Drug metabolism and pharmacokinetics","studyType":"Clinical Study"},{"pmid":"34984313","year":"2021","title":"Human Organic Anion Transporting Polypeptides 1B1, 1B3, and 2B1 Are Involved in the Hepatic Uptake of Phenolsulfonphthalein.","finding":"","journal":"ACS omega","studyType":"Clinical Study"}],"tags":[{"label":"phenolsulfonphthalein","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"V04CH03","category":"atc"},{"label":"Active","category":"status"},{"label":"Renal function study","category":"indication"},{"label":"Coloring Agents","category":"pharmacology"},{"label":"Indicators and Reagents","category":"pharmacology"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"fenolipuna","offLabel":[],"synonyms":["phenolsulfonphthalein","fenolipuna","phenol red","phenolsulfonephthalein","phenolsulphonphthalein","sulfonphthal","sulphental","sulphonthal"],"timeline":[],"approvals":[],"brandName":"Fenolipuna","ecosystem":[{"indication":"Renal function study","otherDrugs":[{"name":"inulin","slug":"inulin","company":"Iso Tex"}],"globalPrevalence":null}],"mechanism":{"modality":"Small Molecule","drugClass":"phenolsulfonphthalein","explanation":"Think of it like a dye that gets flushed out of your body through your kidneys. By measuring how quickly this dye is removed, doctors can get an idea of how well your kidneys are working. This helps them diagnose and monitor kidney problems.","oneSentence":"Fenolipuna works by being excreted by the kidneys, allowing for the assessment of renal function.","technicalDetail":"Fenolipuna is a phenolsulfonphthalein that undergoes renal excretion, allowing for the assessment of glomerular filtration rate (GFR) and effective renal plasma flow (ERPF)."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3439","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=phenolsulfonphthalein","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=phenolsulfonphthalein","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:19:04.943277","biosimilars":[],"competitors":[{"drugName":"inulin","drugSlug":"inulin","fdaApproval":"1940-04-30","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"indigo carmine","drugSlug":"indigo-carmine","fdaApproval":"2022-07-08","relationship":"same-class"},{"drugName":"aminohippuric acid","drugSlug":"aminohippuric-acid","fdaApproval":"1944-12-30","relationship":"same-class"}],"genericName":"phenolsulfonphthalein","indications":{"approved":[{"name":"Renal function study","source":"DrugCentral","snomedId":44277000,"regulator":"FDA"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"inulin","brandName":"inulin","genericName":"inulin","approvalYear":"1940","relationship":"same-class"},{"drugId":"indigo-carmine","brandName":"indigo carmine","genericName":"indigo carmine","approvalYear":"2022","relationship":"same-class"},{"drugId":"aminohippuric-acid","brandName":"aminohippuric acid","genericName":"aminohippuric acid","approvalYear":"1944","relationship":"same-class"}],"trialDetails":[{"nctId":"NCT01705899","phase":"PHASE1","title":"Islet Allotransplantation in Type 1 Diabetes","status":"SUSPENDED","sponsor":"Ohio State University","startDate":"2006-11","conditions":["Type 1 Diabetes"],"enrollment":20,"completionDate":"2033-10"},{"nctId":"NCT04027036","phase":"PHASE2","title":"Comparison of Immunogenicity of Inactivated Poliovirus Vaccine (IPV) Administered Intramuscularly or Intradermally","status":"COMPLETED","sponsor":"Instituto Nacional de Saúde, Mozambique","startDate":"2020-08-06","conditions":["Polio"],"enrollment":382,"completionDate":"2022-05-31"},{"nctId":"NCT05934825","phase":"PHASE1,PHASE2","title":"Clinical Trial to Evaluate Safety and Efficiency of Mesenchymal Stem Cell in Patients With Hidradenitis Suppurativa","status":"UNKNOWN","sponsor":"Andalusian Network for Design and Translation of Advanced Therapies","startDate":"2022-10-26","conditions":["Hidradenitis Suppurativa"],"enrollment":30,"completionDate":"2025-10-26"},{"nctId":"NCT02580201","phase":"PHASE4","title":"A Study to Evaluate Safety and Immunogenicity of tOPV in 1 to 5 Years and at 6 Weeks of Age","status":"COMPLETED","sponsor":"Fidec Corporation","startDate":"2015-11","conditions":["Poliomyelitis"],"enrollment":154,"completionDate":"2016-08-11"},{"nctId":"NCT00350337","phase":"PHASE2","title":"Safety and Immunogenicity of Various Formulations of Live Attenuated Tetravalent Dengue Vaccine in Healthy US Adults","status":"COMPLETED","sponsor":"U.S. Army Medical Research and Development Command","startDate":"2006-04-05","conditions":["Dengue"],"enrollment":86,"completionDate":"2008-03-13"},{"nctId":"NCT02806869","phase":"NA","title":"Modernization of in vivo-in Vitro Oral Bioperformance Prediction and Assessment","status":"COMPLETED","sponsor":"University of Michigan","startDate":"2015-01","conditions":["Human Gastrointestinal Physiology Data"],"enrollment":48,"completionDate":"2017-07"}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NUI":"N0000146443","NDDF":"002339","UNII":"I6G9Y0J1OJ","VUID":"4018105","CHEBI":"CHEBI:31991","VANDF":"4018105","RXNORM":"8141","UMLSCUI":"C0031430","ChEMBL_ID":"CHEMBL258921","KEGG_DRUG":"D01200","DRUGBANK_ID":"DB13212","PUBCHEM_CID":"4766","MESH_DESCRIPTOR_UI":"D010637"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Nephrology"],"atcClassification":{"source":"DrugCentral","atcCode":"V04CH03","allCodes":["V04CH03"]},"biosimilarFilings":[],"recentPublications":[{"date":"2025","pmid":"40324845","title":"Investigation of new non-toxic inhibitors of fibril formation and preservatives for insulin preparations its analogues.","journal":"Advances in protein chemistry and structural biology"},{"date":"2025 Feb","pmid":"39705742","title":"Evaluation of prevalence, risk factors, and therapeutic approach for subclinical endometritis and oviductal occlusion in repeat breeder Holstein cattle.","journal":"Research in veterinary science"},{"date":"2022 Mar 26","pmid":"35351207","title":"Voriconazole injection may induce delayed methotrexate excretion: a case report and experimental study.","journal":"Journal of pharmaceutical health care and sciences"},{"date":"2022 Jun","pmid":"35299026","title":"Phenolsulfonphthalein as a surrogate substrate to assess altered function of the prostaglandin transporter SLCO2A1.","journal":"Drug metabolism and pharmacokinetics"},{"date":"2021 Dec 28","pmid":"34984313","title":"Human Organic Anion Transporting Polypeptides 1B1, 1B3, and 2B1 Are Involved in the Hepatic Uptake of Phenolsulfonphthalein.","journal":"ACS omega"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Fenolipuna is a small molecule with the synonyms NSC-10459 and Phenolsulfonphthalein. It is used as a pH indicator in cell biology laboratories.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}