{"id":"peritoneal-dialysate-at-37-c-temperature","safety":{"commonSideEffects":[{"rate":null,"effect":"Peritonitis"},{"rate":null,"effect":"Exit site infection"},{"rate":null,"effect":"Hyperglycemia"},{"rate":null,"effect":"Hypokalemia"},{"rate":null,"effect":"Abdominal discomfort"}]},"_chembl":{"chemblId":"CHEMBL4303347","moleculeType":"Small molecule","molecularWeight":"455.60"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Peritoneal dialysate is a sterile solution instilled into the peritoneal cavity that acts as a medium for diffusion and ultrafiltration. Waste products and excess electrolytes diffuse from the blood across the peritoneal membrane into the dialysate, while the osmotic gradient created by glucose (or other osmotic agents) in the solution draws excess fluid from the bloodstream. Maintaining the dialysate at body temperature (37°C) optimizes the efficiency of these transport processes.","oneSentence":"Peritoneal dialysate at 37°C facilitates the removal of uremic waste products and excess fluid from the blood across the peritoneal membrane during peritoneal dialysis.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:34:07.606Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"End-stage renal disease (ESRD) requiring renal replacement therapy"},{"name":"Acute kidney injury in select patients"}]},"trialDetails":[{"nctId":"NCT04394780","phase":"NA","title":"Peritoneal Dialysis Fluid Cooling and Cardio-Protective Effects","status":"COMPLETED","sponsor":"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","startDate":"2016-01-11","conditions":"Dialysis; Complications","enrollment":8},{"nctId":"NCT04302649","phase":"PHASE4","title":"Dialysate Temperature in Peritoneal Dialysis","status":"COMPLETED","sponsor":"Azienda Ospedaliero-Universitaria di Modena","startDate":"2018-10-01","conditions":"Peritoneal Dialysis Complication","enrollment":18}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"peritoneal dialysate at 37°C temperature","genericName":"peritoneal dialysate at 37°C temperature","companyName":"Azienda Ospedaliero-Universitaria di Modena","companyId":"azienda-ospedaliero-universitaria-di-modena","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Peritoneal dialysate at 37°C facilitates the removal of uremic waste products and excess fluid from the blood across the peritoneal membrane during peritoneal dialysis. Used for End-stage renal disease (ESRD) requiring renal replacement therapy, Acute kidney injury in select patients.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}