{"id":"pentorex","rwe":[],"tags":[{"label":"pentorex","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Weight loss","category":"indication"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"phenpentermine","offLabel":[],"synonyms":["pentorex","phenpentermine","dl-Phenpentermine"],"timeline":[],"approvals":[],"brandName":"Phenpentermine","ecosystem":[{"indication":"Weight loss","otherDrugs":[{"name":"liraglutide","slug":"liraglutide","company":"Novo Nordisk Inc"},{"name":"semaglutide","slug":"semaglutide","company":"Novo Nordisk Inc"}],"globalPrevalence":890000000}],"mechanism":{"modality":"Small Molecule","drugClass":"pentorex","explanation":"Imagine your brain has a 'full' and 'hungry' switch. Phenpentermine helps flip the 'full' switch by increasing the levels of certain chemicals that tell your brain you're satisfied, making you eat less. This can lead to weight loss.","oneSentence":"Phenpentermine works by increasing the levels of certain neurotransmitters in the brain that help regulate appetite and metabolism.","technicalDetail":"Phenpentermine is a central nervous system stimulant that acts as a norepinephrine-dopamine reuptake inhibitor, increasing the levels of these neurotransmitters in the brain and promoting feelings of fullness and reduced appetite."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3426","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=PENTOREX","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:17:17.537924","biosimilars":[],"competitors":[],"genericName":"pentorex","indications":{"approved":[{"name":"Weight loss","source":"DrugCentral","snomedId":89362005,"regulator":"FDA","usPrevalence":null,"globalPrevalence":890000000,"prevalenceMethod":"curated","prevalenceSource":"WHO, 2024"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"K97CJK0FXR","CHEBI":"CHEBI:134795","INN_ID":"2048","UMLSCUI":"C1882317","ChEMBL_ID":"CHEMBL2105389","PUBCHEM_CID":"22031","MESH_SUPPLEMENTAL_RECORD_UI":"C000080"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Metabolic"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Phenpentermine, also known as Pentorex, is a small molecule drug in the pentorex class. It is used to treat weight loss, but its target is unknown. The commercial status of Phenpentermine is unclear, and it may be patented or have generic manufacturers. Key safety considerations are not well-documented. Further research is needed to fully understand its pharmacology and safety profile.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":false,"score":2}}