{"id":"pentagestrone-acetate","rwe":[{"pmid":"41906752","year":"2026","title":"Deciphering the conformational change and inhibition of Thermus thermophilus laccase in ionic liquid.","finding":"","journal":"Journal of biomolecular structure & dynamics","studyType":"Clinical Study"},{"pmid":"41906696","year":"2026","title":"Chemical constituents of exosome-like nanoparticles-enriched vesicle fraction derived from Sparassis crispa and its biological and molecular docking studies.","finding":"","journal":"International journal of cosmetic science","studyType":"Clinical Study"},{"pmid":"41905700","year":"2026","title":"Effect of octreotide-deoxycholate hydrophobic ion pairing solid dispersions on intestinal permeability to enhance octreotide absorption via increased lipophilicity and ASBT-mediated transport.","finding":"","journal":"International journal of pharmaceutics","studyType":"Clinical Study"},{"pmid":"41905142","year":"2026","title":"Biphasic conversion of bread waste to 5-hydroxymethylfurfural: Process optimization and isolation.","finding":"","journal":"Journal of environmental management","studyType":"Clinical Study"},{"pmid":"41905113","year":"2026","title":"Retraction notice to \"The use of oral nomegestrol acetate/estradiol in rapid and random start preparation of endometrium before office hysteroscopic polypectomies: A multicenter, prospective, randomized controlled trial\" [Eur. J. Obstet. Gynecol. Reprod. Biol. 299 (2024) 213-218].","finding":"","journal":"European journal of obstetrics, gynecology, and reproductive biology","studyType":"Clinical Study"}],"tags":[{"label":"pentagestrone acetate","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"gestovis","offLabel":[],"synonyms":["pentagestrone acetate","gestovis"],"timeline":[],"approvals":[],"brandName":"Gestovis","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"pentagestrone acetate","explanation":"Imagine your body has locks on cells that only open with a special key. Progesterone is that key, and pentagestrone acetate is a copy of the key that can fit into those locks and unlock the cells, allowing them to function properly.","oneSentence":"Pentagestrone acetate is a progestin that works by binding to progesterone receptors in the body, mimicking the effects of the natural hormone progesterone.","technicalDetail":"Pentagestrone acetate acts as a selective progesterone receptor modulator, binding to the progesterone receptor and influencing gene expression and cellular activity."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2089","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=pentagestrone acetate","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:16:03.995061","biosimilars":[],"competitors":[],"genericName":"pentagestrone acetate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"3Y30374T6H","CHEBI":"CHEBI:135718","INN_ID":"1672","UMLSCUI":"C5418508","PUBCHEM_CID":"10321047"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":179843,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2026 Mar 30","pmid":"41906752","title":"Deciphering the conformational change and inhibition of Thermus thermophilus laccase in ionic liquid.","journal":"Journal of biomolecular structure & dynamics"},{"date":"2026 Mar 30","pmid":"41906696","title":"Chemical constituents of exosome-like nanoparticles-enriched vesicle fraction derived from Sparassis crispa and its biological and molecular docking studies.","journal":"International journal of cosmetic science"},{"date":"2026 Mar 27","pmid":"41905700","title":"Effect of octreotide-deoxycholate hydrophobic ion pairing solid dispersions on intestinal permeability to enhance octreotide absorption via increased lipophilicity and ASBT-mediated transport.","journal":"International journal of pharmaceutics"},{"date":"2026 Mar 28","pmid":"41905142","title":"Biphasic conversion of bread waste to 5-hydroxymethylfurfural: Process optimization and isolation.","journal":"Journal of environmental management"},{"date":"2026 Mar 28","pmid":"41905113","title":"Retraction notice to \"The use of oral nomegestrol acetate/estradiol in rapid and random start preparation of endometrium before office hysteroscopic polypectomies: A multicenter, prospective, randomized controlled trial\" [Eur. J. Obstet. Gynecol. Reprod. Biol. 299 (2024) 213-218].","journal":"European journal of obstetrics, gynecology, and reproductive biology"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Gestovis, also known as pentagestrone acetate, is a small molecule drug in the pentagestrone acetate class. Unfortunately, there is limited information available on this compound. It is not clear what specific condition or disease it is intended to treat. Gestovis is not currently listed as an approved medication by the FDA, and its commercial status is unknown. Further research is needed to determine its safety and efficacy.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}