{"id":"pentacel-dptap-hib","safety":{"commonSideEffects":[{"rate":"25-50","effect":"Injection site reactions (pain, redness, swelling)"},{"rate":"10-25","effect":"Fever"},{"rate":"10-20","effect":"Irritability"},{"rate":"5-15","effect":"Drowsiness"},{"rate":"5-10","effect":"Loss of appetite"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The vaccine contains inactivated toxins from diphtheria and tetanus bacteria, acellular pertussis antigens, and Hib polysaccharide conjugate. These components trigger adaptive immune responses that generate protective antibodies and cellular immunity against these four pathogens, preventing infection and disease.","oneSentence":"Pentacel is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, pertussis, tetanus, and Haemophilus influenzae type b (Hib) bacteria.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:36:36.053Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Active immunization against diphtheria, pertussis, tetanus, and Haemophilus influenzae type b in infants and children"}]},"trialDetails":[{"nctId":"NCT00390130","phase":"PHASE4","title":"Does the Order in Which Vaccines Are Administered Affect Pain Response?","status":"COMPLETED","sponsor":"The Hospital for Sick Children","startDate":"2006-07","conditions":"Pain","enrollment":120}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Pentacel (DPTaP+Hib)","genericName":"Pentacel (DPTaP+Hib)","companyName":"The Hospital for Sick Children","companyId":"the-hospital-for-sick-children","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Pentacel is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, pertussis, tetanus, and Haemophilus influenzae type b (Hib) bacteria. Used for Active immunization against diphtheria, pertussis, tetanus, and Haemophilus influenzae type b in infants and children.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}